Results 181 to 190 of about 191,176 (260)

CD38 endows local antigen-specific T_reg cells with stress resilience for control of compartmentalized CNS inflammation. [PDF]

Nat Immunol
Chen HH, Tyystjärvi S, Ruiz Navarro D, Kant R, Groll T, Wagner I, Domínguez Moreno H, Bonafonte-Pardàs I, Öllinger R, Afzali AM, Heink S, Richter LC, Sie C, Lepennetier G, Seeholzer L, Steiger K, Merkler D, Rad R, Schotta G, Schubert B, Muschaweckh A, Korn T.   +21 more
europepmc   +1 more source

Programmable Semi‐Interpenetrating Living Materials With Robust Stability for Versatile Bioremediation and Biotherapeutics

Advanced Science, EarlyView.
A semi‐interpenetrating engineered living material (sIHSELM), fabricated via thermosensitive hydroxybutyl chitosan and covalent protein self‐assembly, demonstrates exceptional mechanical properties and environmental stability. Shielding bacteria from harsh conditions, sIHSELM exhibits remarkable efficacy in ulcerative colitis treatment and pollutants ...
Zixian Bao, Shengfeng Yang, Dandan Hu, Jiezheng Liu, Bo Jiang, Xinyue Sui, Qingsheng Qi, Lai Li, Guang Zhao   +8 more
wiley   +1 more source

Treg cells promote decidual vascular remodeling and modulate uterine NK cells in pregnant mice. [PDF]

JCI Insight
Hosking SL, Moldenhauer LM, Tran HM, Chan HY, Groome HM, Lovell EA, Green ES, O'Hara SE, Roberts CT, Foyle KL, Davidge ST, Robertson SA, Care AS.   +12 more
europepmc   +1 more source

Tumor‐Induced Splenic Remodeling: Mechanisms of Systemic Immunosuppression and Emerging Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley   +1 more source

Cryoablation-induced modulation of Treg cells and the TGF-β pathway in lung adenocarcinoma: implications for increased antitumor immunity. [PDF]

BMC Med
Lin S, Liu D, Liang T, Zhuang Y, Wang X, Ma S, Li Q, Hu K.   +7 more
europepmc   +1 more source

High‐Sensitive Mass Cytometry Metal Tags Based on Noble Metal Nanoparticles Assisting Acute Myeloid Leukemia Immune Checkpoint Profiling

Advanced Science, EarlyView.
ABSTRACT Mass cytometry is optimal for acute leukemia immune checkpoint profiling. However, current commercial metal‐chelating polymer (MCP) metal tags limit its sensitivity due to low metal loading capacity. We report a novel synthetic strategy employing antibody‐conjugated gold or platinum nanoparticles (AuNP/PtNP) for high‐dimensional single‐cell ...
Zhizhou Liu, Yu Yang, Lingfei Qiu, Yi Yang, Jingrui Li, Juan Yue, Yinghui Li, Yingdai Gao, Pengli Bai   +8 more
wiley   +1 more source

Glut3 promotes cellular O-GlcNAcylation as a distinctive tumor-supportive feature in Treg cells. [PDF]

Cell Mol Immunol
Sharma A, Sharma G, Gao Z, Li K, Li M, Wu M, Kim CJ, Chen Y, Gautam A, Choi HB, Kim J, Kwak JM, Lam SM, Shui G, Paul S, Feng Y, Kang K, Im SH, Rudra D.   +18 more
europepmc   +1 more source

Post‐Translational Regulation of CD8+ T Cell Fate and Dysfunction in Tumor Immunity

Advanced Science, EarlyView.
This review delineates how post‐translational modifications (PTMs) function as a central regulatory interface governing CD8+ T cell activation, differentiation, persistence, and exhaustion in antitumor immunity. By integrating antigenic, metabolic, and microenvironmental cues, diverse PTM programs coordinate transcriptional and chromatin states that ...
Zihao Zhou, Xu Chen, Nina Li, Meiyan Zou, Yunfan Lin, Pei Lin, Weiyao Feng, Xinyuan Zhao, Li Cui   +8 more
wiley   +1 more source

Unlocking the Role of Treg Cells Immune Response and Infectious Risk Following CAR T-Cell Therapy in Patients with Cancer. [PDF]

Int J Mol Sci
Dicharry D, Malek AE.
europepmc   +1 more source

Th2 memory cell–derived Treg cells [PDF]

Science-Business eXchange, 2010
openaire   +1 more source