Results 331 to 340 of about 203,023 (389)

Signaling Pathways of the Acquired Immune System and Myocardial Dysfunction in Chronic Kidney Disease-What Do We Know So Far? [PDF]

Biomolecules
Duni A, Georgopoulos C, Kitsos A, Markopoulos G, Dova L, Vartholomatos G, Dounousi E.   +6 more
europepmc   +1 more source

A Supramolecular Nanoscavengers: Based “Cargo‐Exchange” Breaking Cholesterol Metabolic Dysregulation for Glioblastoma Therapy

Advanced Science, EarlyView.
Dysregulated cholesterol metabolism, driven by a complex array of mechanisms, is a defining characteristic of glioblastoma (GBM). In this study, supramolecular nanoscavengers are engineered by harnessing the intrinsic binding affinity between endogenous small‐molecule cholesterol and β‐cyclodextrin (β‐CD).
Zonghua Tian, Yun Chen, Jingyi Zhou, Shilin Zhang, Hongrui Fan, Xuwen Li, Tao Sun, Chen Jiang   +7 more
wiley   +1 more source

FOXP3+ T Cells-An Emerging Evidence in Periodontitis Therapeutics. [PDF]

Clin Exp Dent Res
Ünsal RBK, Hasuike A, Badawy T, Asa'ad F, Špiljak B, Yuwanati M, Roganović J, Liu Y, Brigi C, Zambrano DM, Chaurasia A.   +10 more
europepmc   +1 more source

Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1+ Macrophages to Foster Liver Metastasis, Targeted by Indole‐3‐Acetic Acid

Advanced Science, EarlyView.
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang, Shipeng Dai, Yuchen Xie, Pengyu Chen, Yue Chai, Chongyu Wang, Xueying Huang, Xiao Dong, Junfeng Shi, Yongxiang Xia, Xiaofeng Qian, Weiwei Tang, Yichan Zhou   +12 more
wiley   +1 more source

Celastrol Activates HSF1 to Enhance Regulatory T Cells Function and Ameliorate Intestinal Inflammation. [PDF]

Biomolecules
Alula KM, Collins CB, Nguyen TT, Aherne CM, Jedlicka P, de Zoeten EF.   +5 more
europepmc   +1 more source

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

Advanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li, Yumei Wang, Xiaoxi Fan, Miao Xu, Jiawen Li, Wenfei Tan, Jianxiang Zhang, Heran Li   +7 more
wiley   +1 more source

CD39⁺PD-1⁺ regulatory T cells in melanoma: key drivers of systemic immunosuppression and prognostic biomarkers. [PDF]

Front Oncol
Qiao G, He H, Wang X.
europepmc   +1 more source

BHLHE40 Orchestrates Effector Tissue‐Resident Memory CD8+ T Cells and Limits Long‐Term Survival of Kidney Graft

Advanced Science, EarlyView.
An effector subset of TRM, defined as CD49a+PD1hi CD8+ TRM, represents a BHLHE40‐orchestrated resident immune component that, rather than circulating cells, plays as a major contributor to allograft rejection. ABSTRACT Tissue‐resident memory T cells (TRM), which function against tumors, infections, and non‐self antigens in organ transplantation ...
Junbo Li, Bo Yang, Tianhui Pan, Xi Zhou, Zhibo Ma, Du Tang, Bowen Xie, Jing Liu, Zhishui Chen, Peixiang Lan   +9 more
wiley   +1 more source

Immunomodulatory effect of ultrasound-guided cryoablation in early breast cancer: pilot study on blood and surgical samples. [PDF]

Eur Radiol Exp
Pediconi F, Galati F, Nuti M, Rizzo V, Botticelli A, Tuosto L, Pace A, Rughetti A, d'Amati G, Cerbelli B, Napoletano C.   +10 more
europepmc   +1 more source

The Immunology of pulmonary fibrosis: The role of Th1/Th2/Th17/Treg cells

, 2010
Demosthenes Bouros, Αrgyris Τzouvelekis, Evangelos Bouros   +2 more
openalex   +1 more source