Results 361 to 370 of about 203,023 (389)

Tumor microenvironment in gastric cancer immune tolerance and its therapeutic relevance in immunomodulation (Review). [PDF]

Oncol Lett
Guan Z, Han L, Chen B, Ma Y, Ni Q, Wang Z, Yang J, Liu Z.   +7 more
europepmc   +1 more source

Effect of Lactobacillus salivarius on Th1/Th2 cytokines and the number of spleen CD4⁺ CD25⁺ Foxp3⁺ Treg in asthma Balb/c mouse.

, 2015
Yun Xiang, Yunxiao Shang, Miao Li
openalex   +1 more source

Tregs With High CD29 Expression Promote Cell Adhesion and Contribute to the Malignant Transformation of MASLD. [PDF]

Liver Int
Lu Y, Liu L, Zhou M, Zou M, Ju L, Yao D, Yao M.   +6 more
europepmc   +1 more source

Discovery of Seven ROS-Sensitive Immune Checkpoints and 46 Ligands Mediating Immune Suppression Through T cell-APC Networks. [PDF]

J Cancer
Han B, Xu K, Saaoud F, Hou Y, Shao Y, Lu Y, Jiang X, Zhao H, Wang H, Yang X.   +9 more
europepmc   +1 more source

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Pancreatic islet-specific engineered Tregs exhibit robust antigen-specific and bystander immune suppression in type 1 diabetes models

Science Translational Medicine, 2022
Adoptive transfer of regulatory T cells (Tregs) is therapeutic in type 1 diabetes (T1D) mouse models. Tregs that are specific for pancreatic islets are more potent than polyclonal Tregs in preventing disease.
S. Yang, Akhilesh K. Singh, Travis Drow, Tori Tappen, Yuchi Honaker, Fariba Barahmand-pour-Whitman, P. Linsley, K. Cerosaletti, Kelsey E. Mauk, Yufei Xiang, Jessica Smith, Emma Mortensen, Peter J. Cook, Karen Sommer, Iram Khan, D. Liggitt, D. Rawlings, J. Buckner   +17 more
semanticscholar   +1 more source

Treg cells in atherosclerosis

Molecular Biology Reports, 2021
Atherosclerosis involves both innate and adaptive immunity. Here, we provide an overview of the role of regulatory T (Treg) cells in atherosclerotic diseases. Treg cells and their inhibitory cytokines, IL-10 and TGF-β, have been identified in atherosclerotic lesions and to inhibit progression through lipoprotein metabolism modulation.
Rebecca Kuan, Devendra K. Agrawal, Finosh G. Thankam   +2 more
openaire   +2 more sources

Treg and lupus

Annals of the Rheumatic Diseases, 2010
Autoimmune diseases such as systemic lupus erythemathodes (SLE) display quantitative and/or qualitative deficiencies of CD4+CD25+ regulatory T cells (Treg). This might contribute to the immune dysregulation and break-down of peripheral tolerance mechanisms.
M, Bonelli, J S, Smolen, C, Scheinecker
openaire   +2 more sources

Tregs

Current Opinion in Organ Transplantation, 2012
Transfer of human regulatory T cells (Tregs) has become an attractive therapeutic alternative to improve the long-term outcome in transplantation and thus reduce the side-effects of conventional immunosuppressive drugs. Here, we summarize the recent findings on human Treg subsets, their phenotype and in-vivo function.In the last 2 years, it has become ...
Ulrike Schlieer, Mathias Streitz, Birgit Sawitzki   +2 more
openaire   +2 more sources

Differentiation of Peripheral Treg

2022
This chapter shows protocols for the differentiation of peripheral Treg (pTreg) from polyclonal and monoclonal CD4+ T cells. Polyclonal naïve CD4+ T cells can differentiate into pTreg upon adoptive transfer into Foxp3-diphtheria toxin receptor transgenic recipient mice in which endogenous Tregs are transiently depleted by administration of diphtheria ...
José, Almeida-Santos, Marie-Louise, Bergman, Jocelyne, Demengeot   +2 more
openaire   +2 more sources

Visceral adipose tissue Tregs and the cells that nurture them

Immunological Reviews, 2020
Visceral adipose tissue (VAT) is a primary site for storage of excess energy, but it also serves as an important endocrine organ that impacts organismal metabolism.
Chaoran Li, R. Spallanzani, D. Mathis
semanticscholar   +1 more source