Results 41 to 50 of about 7,382 (215)

Screening and characterization of food-derived trehalase inhibitors

open access: yesFood Science and Human Wellness
Trehalose is an autophagy-promoting disaccharide, which can improve and delay chronic diseases like neurodegenerative diseases and atherosclerosis, but its bioavailability is severely restricted by endogenous trehalase in mammals.
Yanmei Zhang   +6 more
doaj   +1 more source

Validamycin Inhibits the Synthesis and Metabolism of Trehalose and Chitin in the Oriental Fruit Fly, Bactrocera dorsalis (Hendel)

open access: yesInsects, 2023
The oriental fruit fly, Bactrocera dorsalis (Hendel), is a notorious invasive pest that has raised concerns worldwide. Validamycin has been demonstrated to be a very strong inhibitor against trehalase in a variety of organisms.
Ying Li   +6 more
doaj   +1 more source

Intracellular trehalase of a hybrid yeast [PDF]

open access: yesBiochemical Journal, 1965
1. The trehalase found in an extract prepared from a yeast strain that cannot ferment trehalose was studied and characterized. The enzyme is highly specific for trehalose with K(m) 1.02x10(-2)m, and an optimum pH of 6.9. 2. It is inhibited by glucose and by trehalose 6-phosphate, and does not facilitate any significant transglucosylations. 3. pK values
G, Avigad, O, Ziv, E, Neufeld
openaire   +2 more sources

Trehalases and trehalose hydrolysis in fungi [PDF]

open access: yesFEMS Microbiology Letters, 2006
The simultaneous presence of two different trehalose-hydrolysing activities has been recognised in several fungal species. While these enzymes, known as acid and neutral trehalases, share a strict specificity for trehalose, they are nevertheless rather different in subcellular localisation and in several biochemical and regulatory properties.
J A, Jorge   +3 more
openaire   +2 more sources

Peptidic product derived from trypsin autolysis modulates insect digestive proteases and supports plant biochemical defense

open access: yesPest Management Science, EarlyView.
XXXX Abstract BACKGROUND Spodoptera frugiperda, commonly known as the fall armyworm, is a highly economically significant pest that affects various crops, resulting in substantial losses in productivity. Managing this pest primarily relies on chemical insecticides; however, the repeated development of resistance to these chemicals has rendered them ...
Daniel Guimarães Silva Paulo   +9 more
wiley   +1 more source

Exploring plant tolerance to biotic and abiotic stresses [PDF]

open access: yes, 2007
Plants are exposed to many stress factors, such as drought, high salinity or pathogens, which reduce the yield of the cultivated plants or affect the quality of the harvested products. Arabidopsis thaliana was used as a model plant to study the responses
Karim, Sazzad
core  

Comparative metabolomics in primates reveals the effects of diet and gene regulatory variation on metabolic divergence. [PDF]

open access: yes, 2014
Human diets differ from those of non-human primates. Among few obvious differences, humans consume more meat than most non-human primates and regularly cook their food.
Blekhman, Ran   +5 more
core   +2 more sources

NEUROSPORA TREHALASE AND ITS STRUCTURAL GENE [PDF]

open access: yesGenetics, 1985
ABSTRACT We have isolated Neurospora trehalaseless mutants and mapped the trehalase structural gene to linkage group I. The structural gene mutations not only affect thermostability and other characteristics of the enzyme but also affect the production of an inhibitor of the wild-type trehalase.
C, White, D B, Lee, S J, Free
openaire   +2 more sources

Comparison of Three Sympatric Desert Lizards: Digestive Tract Structure, Digestive Enzyme Activities, Gut Microbiota, and Metabolites

open access: yesIntegrative Zoology, EarlyView.
We performed 16S rDNA sequencing and metabolite profiling for three sympatric lizard species—Teratoscincus roborowskii, Phrynocephalus axillaris, and Eremias roborowskii—and compared their goblet cell and enzyme activities in the digestive tract. Our study suggests that the dietary niche may promote divergence or convergence of microbiota across host ...
Yi Yang, Ziyi Wang, Ruichen Wu
wiley   +1 more source

Evaluation of the Expression and Function of the TRE2-like and TRE2 Genes in Ecdysis of Harmonia axyridis

open access: yesFrontiers in Physiology, 2019
Harmonia axyridis is an important predatory insect and widely used in biological control of agricultural and forestry pests. Trehalose is directly involved in the energy storage of the H.
Yan Li   +6 more
doaj   +1 more source

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