Trehalose-based neuroprotective autophagy inducers
, 2021 A small set of trehalose-centered putative autophagy inducers was rationally designed and synthesized, with the aim to identify more potent and bioavailable autophagy inducers than free trehalose, and to acquire information about their molecular ...
Assoni G. +17 more
core +1 more source
Counteraction of Trehalose on N, N-Dimethylformamide-Induced Candida rugosa Lipase Denaturation: Spectroscopic Insight and Molecular Dynamic Simulation. [PDF]
PLoS ONE, 2016 Candida rugosa lipase (CRL) has been widely used as a biocatalyst for non-aqueous synthesis in biotechnological applications, which, however, often suffers significant loss of activity in organic solvent.
Xin Yang +6 more
doaj +1 more source
Trehalose is required for the acquisition of tolerance to a variety of stresses in the filamentous fungus Aspergillus nidulans [PDF]
, 2001 Trehalose is a non-reducing disaccharide found at high concentrations in Aspergillus nidulans conidia and rapidly degraded upon induction of conidial germination. Furthermore, trehalose is accumulated in response to a heat shock or to an oxidative shock.
Chaveroche, M. +6 more
core
Enzymatic Processes for the Purification of Trehalose
, 2014 A dual-enzyme process aiming at facilitating the purification of trehalose from maltose isreported in this study. Enzymatic conversion of maltose to trehalose usually leads to thepresence of significant amount of glucose, by-product of the reaction, and ...
Sung-Chyr Lin, Tsung-Ta Wu, Je-Fu Shaw
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Trehalose maintains vitality of mouse epididymal epithelial cells and mediates gene transfer. [PDF]
PLoS ONE, 2014 In the present study, trehalose was utilized to improve primary culture of mouse epididymal epithelial cells in vitro, and to enhance naked DNA delivery in epididymis in vivo.
Bin Qu +7 more
doaj +1 more source
A Glial Interplay Regulates Junctional Architecture at the Blood-Brain Barrier of Drosophila. [PDF]
GliaDrosophila perineurial glia are required for septate junction formation at the blood–brain barrier. Glucose transport across the blood–brain barrier is maintained in the absence of perineurial glia. Perineurial glia ablation increases glucose‐only diet sensitivity.
Contreras EG +7 more
europepmc +2 more sources
FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
An investigation on interaction between trehalose and ascorbic acid on some growth parameters and photosynthetic gene expression in Arabidopsis thaliana seedlings [PDF]
Zīst/shināsī-i Giyāhī-i Īrān, 2014 Trehalose is an α-α linked glucose disaccharide. Trehalose supplied to the growth medium of Arabidopsis seedlings inhibits root growth, primary leaf development and carbon allocation from shoot to root.
Hamid Sadeghipour +3 more
doaj
Effects of starvation on the carbohydrate metabolism in Harmonia axyridis (Pallas)
Biology Open, 2017 Trehalose plays an important role in energy storage, metabolism, and protection from extreme environmental conditions in insects. Trehalose is the main blood sugar in insects, and it can be rapidly used as an energy source in times of need.
Zuo-Kun Shi +7 more
doaj +1 more source