Results 41 to 50 of about 55,627 (244)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Counteraction of Trehalose on N, N-Dimethylformamide-Induced Candida rugosa Lipase Denaturation: Spectroscopic Insight and Molecular Dynamic Simulation. [PDF]

PLoS ONE, 2016
Candida rugosa lipase (CRL) has been widely used as a biocatalyst for non-aqueous synthesis in biotechnological applications, which, however, often suffers significant loss of activity in organic solvent.
Xin Yang, Ling Jiang, Yigang Jia, Yi Hu, Qing Xu, Xian Xu, He Huang   +6 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

An investigation on interaction between trehalose and ascorbic acid on some growth parameters and photosynthetic gene expression in Arabidopsis thaliana seedlings [PDF]

Zīst/shināsī-i Giyāhī-i Īrān, 2014
Trehalose is an α-α linked glucose disaccharide. Trehalose supplied to the growth medium of Arabidopsis seedlings inhibits root growth, primary leaf development and carbon allocation from shoot to root.
Hamid Sadeghipour, Mahnaz Aghdasi, Nadia Rezaeean, Mahnaz Aghdasi   +3 more
doaj  

A Snapshot of the Trehalose Pathway During Seed Imbibition in Medicago truncatula Reveals Temporal- and Stress-Dependent Shifts in Gene Expression Patterns Associated With Metabolite Changes

Frontiers in Plant Science, 2019
Trehalose, a non-reducing disaccharide with multiple functions, among which source of energy and carbon, stress protectant, and signaling molecule, has been mainly studied in relation to plant development and response to stress.
Anca Macovei, Andrea Pagano, Michela Cappuccio, Michela Cappuccio, Lucia Gallotti, Daniele Dondi, Susana De Sousa Araujo, Pedro Fevereiro, Pedro Fevereiro, Alma Balestrazzi   +9 more
doaj   +1 more source

Trehalose maintains vitality of mouse epididymal epithelial cells and mediates gene transfer. [PDF]

PLoS ONE, 2014
In the present study, trehalose was utilized to improve primary culture of mouse epididymal epithelial cells in vitro, and to enhance naked DNA delivery in epididymis in vivo.
Bin Qu, Yihua Gu, Jian Shen, Jinzhou Qin, Jianqiang Bao, Yuan Hu, Wenxian Zeng, Wuzi Dong   +7 more
doaj   +1 more source

Sustainable and Multifunctional Natural Macromolecular Polymers for Aqueous Zn Metal Batteries

Advanced Materials, EarlyView.
We comprehensively review the structure‐function relationships and regulatory mechanism of natural macromolecular polymers in stabilizing zinc anodes at the microscopic and mesoscopic scales. The interactions among polymer structures, optimization strategies, and regulatory mechanisms are discussed systematically summarizing recent related research ...
Yunuo Shi, Bo Jiang, Jingcheng Zhang, Xiaodong Shao, Peixun Xiong, Lutong Shan, Shengyang Huang, Mengfang Liang, Mengyao Chang, Fangyan Liu, Wenwu Li, Baoyu Xia, Wei Ji, Ho Seok Park   +13 more
wiley   +1 more source

Histone Modification Complex JMJ704‐HDA709 Negatively Regulates Salinity Tolerance in Rice

Advanced Science, EarlyView.
This study reveals that the rice histone demethylase JMJ704 interacts with HDA709―a H3K9ac deacetylase characterized herein―to form a chromatin‐modifying complex. Under salt stress, OsWRKY72 recruits this complex through interaction with JMJ704 to target loci, repressing the expression of oxidative stress and salt‐responsive genes via removal of ...
Jing Wang, Zhengting Chen, Pengxiang Bai, Biao Liu, Lingling Meng, Jian Zhang, Xu Li, Dao‐Xiu Zhou, Xuan Ma, Yu Zhao   +9 more
wiley   +1 more source

Intracellular Delivery of Hydrophilic Glycans Using Superchaotropic Clusters

Angewandte Chemie, EarlyView.
Superchaotropic boron clusters are demonstrated to deliver hydrophilic glycans directly into mammalian cells, removing the need for acetylation and cytotoxic solvents such as DMSO. Azido glycans for metabolic oligosaccharide engineering, and trehalose, were delivered and the successful azido‐labelling of glycoproteins, cell surface glycans, and ...
Qiao Tang, Alexandru Ilie, Matthew I. Gibson   +2 more
wiley   +2 more sources

Trehalose supports the growth of Aedes aegypti cells and modifies gene expression and dengue virus type 2 replication.

PLoS Pathogens
Trehalose is a non-reducing disaccharide that is the major sugar found in insect hemolymph fluid. Trehalose provides energy, and promotes growth, metamorphosis, stress recovery, chitin synthesis, and insect flight.
Andrew D Marten, Douglas P Haslitt, Chad A Martin, Akshitha Karthikeyan, Daniel H Swanson, Karishma Kalera, Ulysses G Johnson, Benjamin M Swarts, Michael J Conway   +8 more
doaj   +1 more source