Results 61 to 70 of about 74,026 (260)
Positive effects of trehalose and cysteine on ram sperm parameters [PDF]
, 2017 WOS: 000401066500002The aim of this study was to determine the effects of trehalose and cysteine on sperm motility, viability, mitochondrial activity and acrosome integrity during liquid storage of Merino ram semen.
Ömür, Ali Doğan +5 more
core +1 more source
In Vivo CRISPR Screen Identifies RPS19 as an Immunotherapy Target in Hepatocellular Carcinoma
Advanced Science, EarlyView.By employing in vivo CRISPR functional screening, we identify ribosomal protein RPS19 as a pivotal mediator driving immune evasion in hepatocellular carcinoma, wherein tumor‑released RPS19 binds C5aR1 on tumor‑associated macrophages to initiate downstream immunosuppressive signaling; SP94‑peptide‑modified SNPSS nanoparticles deliver Cas9/sgRPS19 ...
Lei He +20 more
wiley +1 more source
NUB1 Regulates Muscle Atrophy in Lung Cancer Cachexia via NF‐κB Signaling Pathway
Advanced Science, EarlyView.ABSTRACT Cancer‐associated cachexia (CAC) is a devastating multifactorial syndrome characterized by progressive skeletal muscle atrophy. Its mechanisms remain incompletely clarified, with limited effective therapeutic targets. NUB1, a negative regulator of ubiquitin‐like proteins mediating protein degradation, has not been fully elucidated in CAC ...
Yuqi Han +13 more
wiley +1 more source
Application of trehalose ameliorates heat stress and promotes recovery of winter wheat seedlings
, 2014 Trehalose was supplied to wheat (Triticum aestivum L.) seedlings just before a high temperature (40 °C) treatment and some physiological parameters were measured during the heat stress and recovery.
Y. M. Gao, W. Wang, Y. Luo, C. J. Zou
core +1 more source
Intelligent Polymer Electrolytes for Next‐Generation Zinc‐Based Energy Storage Devices
Advanced Science, EarlyView.Intelligent polymer electrolytes are organized into a three‐level hierarchy that advances zinc‐based energy storage from passive ion conduction toward active, adaptive, and intelligent operation. Molecular regulation of Zn+ coordination, water activity, desolvation, ion flux, and interfaces underpins adaptive self‐healing, anti‐freezing, adhesion, and ...
Sanath Kumar +4 more
wiley +1 more source
Aquaculture NutritionAir exposure stress (AES) is a common stress faced by Chinese mitten crabs (Eriocheir sinensis) in aquaculture and transport. This study was designed to evaluate the levels of endogenous trehalose, oxidative stress, and autophagy in crabs subjected to ...
Anjun Xiang +5 more
doaj +1 more source
Cells, 2021 Adipose tissue senescence is implicated as a major player in obesity- and ageing-related disorders. There is a growing body of research studying relevant mechanisms in age-related diseases, as well as the use of adipose-derived stem cells in regenerative
Conor A. Crowley +4 more
doaj +1 more source
Advanced NanoBiomed Research, EarlyView.Engineered endotoxin‐free Escherichia coli were used to assemble poly(3‐hydroxybutyrate) (PHB) biopolymer particles displaying multiple conserved Burkholderia pseudomallei antigens via PhaC‐mediated surface presentation. Following formulation with poly(I:C), the particulate vaccines induced antigen‐specific humoral and cellular immune responses ...
Md. Tanvir Kabir +6 more
wiley +1 more source
, 2022 IntroductionBackground: This study aimed to investigate the trehalose-induced alterations in serum expression levels of miRNAs associated with vascular inflammation in patients with coronary artery disease (CAD) in order to evaluate the effectiveness of ...
Mitra Abbasifard (9715223) +7 more
core
Biotechnology and Bioengineering, EarlyView.Lifecycle perspective on cell and gene therapy manufacturing challenges and enabling GMP solutions. ABSTRACT Cell and gene therapies (CGTs) are revolutionizing modern medicine; however, making these advanced medicines scalable and readily available to commercial manufacturers worldwide is a major challenge. The number of approved CGT products continues
Rajath Samaga +2 more
wiley +1 more source