Results 81 to 90 of about 99,631 (278)
Current Opinion in Plant Biology, 2007 Trehalose 6-phosphate (T6P) is a sugar signal of emerging significance. It is an essential component of the mechanisms that coordinate metabolism with plant growth adaptation and development. Its significance began to dawn when genetic modification of the trehalose pathway produced dramatic phenotypes, before the genetic proliferation of the trehalose ...
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Advanced Science, EarlyView.ABSTRACT Platelet transfusions to treat bleeding complications use donor‐derived platelets stored at room‐temperature, that have a shelf‐life of only 5–7 days due to bacterial contamination risks. Cold‐stored and freeze‐dried platelets are being investigated for extending shelf‐life, but these still have the inherent challenge of donor‐dependency.
Ujjal Didar Singh Sekhon +20 more
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Current Issues in Molecular BiologyDonation after circulatory death (DCD) is a promising strategy for alleviating donor shortage in heart transplantation. Trehalose, an autophagy inducer, has been shown to be cardioprotective in an ischemia-reperfusion (IR) model; however, its role in IR ...
Jingwen Gao +2 more
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Advanced NanoBiomed Research, EarlyView.Selenium nanoparticles (SeNPs) are emerging as multifunctional platforms for wound healing, integrating antimicrobial, anti‐inflammatory, and proregenerative activities. This review summarises key mechanisms and recent advances in SeNP‐enabled composite dressings, immunomodulatory nanocomposites, microenvironment‐responsive hydrogels, photothermal and ...
Yangxia Chen +10 more
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Trehalose metabolism in Arabidopsis: occurrence of trehalose and molecular cloning and characterization of trehalose‐6‐phosphate synthase homologues [PDF]
Journal of Experimental Botany, 2001 Axenically grown Arabidopsis thaliana plants were analysed for the occurrence of trehalose. Using gas chromatography-mass spectrometry (GC-MS) analysis, trehalose was unambiguously identified in extracts from Arabidopsis inflorescences. In a variety of organisms, the synthesis of trehalose is catalysed by trehalose-6-phosphate synthase (TPS; EC 2.4.1 ...
Vogel, Guido +6 more
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British Journal of Clinical Pharmacology, EarlyView.Aim To develop and validate a physiologically‐based pharmacokinetic (PBPK) model enabling inhaled oxytocin dose selection for clinical evaluation. Subsequently, to conduct a phase 1 study investigating the pharmacokinetics and safety of selected doses of an optimized inhaled oxytocin product in healthy, non‐pregnant female participants.
Pete Lambert +6 more
wiley +1 more source
daf-16/FoxO promotes gluconeogenesis and trehalose synthesis during starvation to support survival
eLife, 2017 daf-16/FoxO is required to survive starvation in Caenorhabditis elegans, but how daf-16IFoxO promotes starvation resistance is unclear. We show that daf-16/FoxO restructures carbohydrate metabolism by driving carbon flux through the glyoxylate shunt and ...
Jonathan D Hibshman +9 more
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EFFECT OF HOT-WATER BLANCHING IN TREHALOSE SOLUTIONS ON BOTH NUTRITIONAL AND TECHNOLOGICAL QUALITY OF SLICED ORGANIC CARROTS [PDF]
, 2018 The aim of the present work was to evaluate the effect of blanching treatments at 75 and 90°C for 3 min in trehalose solution (4% w/v) on nutritional and technological quality of organic carrot (cv. Romance) slices of 5-mm thickness.
Giordana, Ventriglia +2 more
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Trehalose Metabolism of Trypanosomes [PDF]
Nature, 1960 THE trypanosomes causing African sleeping sickness from the blood of man and other animals can be cultivated on non-living media. Such cultures exhibit one striking peculiarity: as soon as established they are not infectious for mammals.
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