Results 71 to 80 of about 55,627 (244)

Safety and Feasibility of Magnetic Separation‐Based Blood Purification

Advanced NanoBiomed Research, EarlyView.
We present the preclinical biological safety and translational feasibility of a magnetic nanoparticle‐based extracorporeal blood purification platform for removal of disease‐causing blood factors. ISO 10993‐compliant studies and exaggerated worst‐case exposure models demonstrate efficient nanoparticle extraction (≥99.9%), favorable biocompatibility ...
Carlos A. Mora, Laurine Rijsbergen, Jan Waskowski, Gaelle Clermont, Florian Dingreville, Chandrashekara Vishwanath, Rajesh Karunanithi, Alexander Gogos, Jean‐Claude Metzger, Manuel Baumgartner, Joerg C. Schefold, Inge K. Herrmann   +11 more
wiley   +1 more source

Trehalose Metabolism of Trypanosomes [PDF]

Nature, 1960
THE trypanosomes causing African sleeping sickness from the blood of man and other animals can be cultivated on non-living media. Such cultures exhibit one striking peculiarity: as soon as established they are not infectious for mammals.
openaire   +2 more sources

daf-16/FoxO promotes gluconeogenesis and trehalose synthesis during starvation to support survival

eLife, 2017
daf-16/FoxO is required to survive starvation in Caenorhabditis elegans, but how daf-16IFoxO promotes starvation resistance is unclear. We show that daf-16/FoxO restructures carbohydrate metabolism by driving carbon flux through the glyoxylate shunt and ...
Jonathan D Hibshman, Alexander E Doan, Brad T Moore, Rebecca EW Kaplan, Anthony Hung, Amy K Webster, Dhaval P Bhatt, Rojin Chitrakar, Matthew D Hirschey, L Ryan Baugh   +9 more
doaj   +1 more source

Challenges and Future Directives of Synthetic Biology in Engineering Plant–Microbe Partnerships for Sustainable Agriculture

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Synthetic biology has recently proven to be a valuable tool for enhancing agriculture even in the face of environmental and biological stresses. Understanding the challenges that militate synthetic biology will assist in ensuring safe, stable, and scalable crop production.
Ben Jesuorsemwen Enagbonma, Rebaona Reaobaka Molefe‐Madlaliso, Alaba Adewole Adebayo, Oghoye Priscilla Oyedoh, Godfrey Okainemen Oribhabor, Oluwaseun Emmanuel Shittu, Olubukola Oluranti Babalola   +6 more
wiley   +1 more source

Enhancing trehalose production via Bacillus species G1 cyclodextrin glucanotransferase mutants: modifying disproportionation characteristics and thermal stability

Frontiers in Microbiology
Inefficient conversion of small molecule maltooligosaccharides into trehalose greatly affects the cost of the production of trehalose by double enzyme method [maltooligosyl trehalose synthase (MTSase) and maltooligosyl trehalose trehalohyrolase (MTHase)].
Bobo Miao, Bobo Miao, Di Huang, Di Huang, Tengfei Wang, Tengfei Wang, Hongling Liu, Hongling Liu, Zhifeng Hao, Haibo Yuan, Haibo Yuan, Yi Jiang, Yi Jiang   +12 more
doaj   +1 more source

Data on the positive synergic action of dimethylacetamide and trehalose on quality of cryopreserved chicken sperm

Data in Brief, 2016
This data article contains supporting information regarding the research article entitled “Combined effect of permeant and non-permeant cryoprotectants on the quality of frozen/thawed chicken sperm”(Mosca et. al., 2016) [1].
Fabio Mosca, Manuela Madeddu, Ahmad Abdel Sayed, Luisa Zaniboni, Nicolaia Iaffaldano, Silvia Cerolini   +5 more
doaj   +1 more source

Machine Learning‐Based PAT Tool for Real‐Time Residual Moisture Monitoring in Lyophilized Biopharmaceuticals Using NIR Spectroscopy

Biotechnology and Bioengineering, EarlyView.
ABSTRACT There is a growing demand in the pharmaceutical industry to optimize analytical methodologies, reducing time and resource consumption while ensuring rapid process development and cost‐efficient manufacturing. Indeed, Food and Drug Administration (FDA) introduced the Process Analytical Technology (PAT) as an initiative enabling manufacturers to
Samuele Fiorenza, Mariapia D'Urso, Ambra Massei, Nunzia Falco, Davide Fissore, Enza Torino   +5 more
wiley   +1 more source

Exogenously-supplied trehalose protects thylakoid membranes of winter wheat from heat-induced damage

Biologia Plantarum, 2010
The effects of trehalose pretreatment on thylakoid membranes of winter wheat were investigated under heat stress. Under normal growth conditions, the winter wheat synthesized 502 μg g-1(f.m.) trehalose, which increased to 1250 μg g-1(f.m.) under heat ...
Y. Luo, F. Li, G. P. Wang, X. H. Yang, W. Wang   +4 more
doaj   +1 more source

Clathrate hydrate crystallization

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract Clathrate hydrate crystallization has been an area of interest to chemical engineers from the point of view of crystal structure, thermophysical properties, phase equilibria, kinetics, industrial applications, and environmental (climate change) implications.
Peter Englezos
wiley   +1 more source

Trehalose Rescues Postmenopausal Osteoporosis Induced by Ovariectomy through Alleviating Osteoblast Pyroptosis via Promoting Autophagy

Biomedicines
Background: Osteoporosis, a prevalent bone metabolic disease, often requires long-term drug treatments that may lead to serious side effects. Trehalose, a natural disaccharide found in various organisms, has been shown to have a promoting effect on ...
Xinli Hu, Wei Wang, Xiaolong Chen, Chao Kong, Xuan Zhao, Zheng Wang, Haojie Zhang, Shibao Lu   +7 more
doaj   +1 more source