Results 101 to 110 of about 7,562,928 (333)

Replacing the Concept of Externalities to Analyze Constraints on Global Economic Growth and Move Toward a New Economic Paradigm

open access: yesCadmus, 2014
The prevailing economic paradigm has fallen short as a guide to policy making in this era of global economic crises. Numerous efforts are underway to revise it or replace it with a science of society that integrates intellectual disciplines.
Jim Lunday
doaj  

Becoming a guide for pilgrims in a time of secularization

open access: yesChurch, Communication and Culture, 2018
The goal of this case study is threefold: first, to introduce the concept of postmodern pilgrim, leveraging on two pilgrimage experiences in Switzerland; second, to propose a model (PEARL) for developing training modules for pilgrim guides; and finally ...
Terry Inglese
doaj   +1 more source

Trends in mechanical fasteners [PDF]

open access: yes, 1972
Some of the specialty fasteners which are enjoying increasing usage are: thread rolling screws, self drilling and tapping screws, locking screws, tamperproof fasteners, and flanged bolts and nuts.
Levy, J. B.
core   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Multi-Layer Modeling and Visualization of Functional Network Connectivity Shows High Performance for the Classification of Schizophrenia and Cognitive Performance via Resting fMRI

open access: yesBioMed
Background: In functional magnetic resonance imaging (fMRI), functional network connectivity (FNC) captures temporal coupling among intrinsic connectivity networks (ICNs).
Duc My Vo   +3 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

A Dynamic Entropy Approach Reveals Reduced Functional Network Connectivity Trajectory Complexity in Schizophrenia

open access: yesEntropy
Over the past decade and a half, dynamic functional imaging has revealed low-dimensional brain connectivity measures, identified potential common human spatial connectivity states, tracked the transition patterns of these states, and demonstrated ...
David Sutherland Blair   +2 more
doaj   +1 more source

Foreign Labor Trends: Malaysia [PDF]

open access: yes, 2002
Foreign Labor Trendsmalaysia_2002.pdf: 20314 downloads, before Oct.
U.S. Department of Labor
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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