Results 51 to 60 of about 935 (139)

Isolation of Treponema DNA from Necrophagous Flies in a Natural Ecosystem

EBioMedicine, 2016
Background: Recently, the World Health Organization launched a campaign to eradicate the tropical disease yaws, caused by the bacterium Treponema pallidum subsp. pertenue; however, for decades researchers have questioned whether flies act as a vector for
Sascha Knauf, Jane Raphael, Oriol Mitjà, Inyasi A.V. Lejora, Idrissa S. Chuma, Emmanuel K. Batamuzi, Julius D. Keyyu, Robert Fyumagwa, Simone Lüert, Charmie Godornes, Hsi Liu, Christiane Schwarz, David Šmajs, Philippe Grange, Dietmar Zinner, Christian Roos, Sheila A. Lukehart   +16 more
doaj   +1 more source

Yaws recurrence in children at continued risk of infection.

PLoS Neglected Tropical Diseases, 2022
BackgroundIn yaws-endemic areas, children with Treponema pallidum subsp. pertenue infection may suffer recurrent episodes due to either reinfection or relapse.
Camila G Beiras, Michael Marks, Llorenç Quintó, Sergi Gavilán, Reman Kolmau, Maria Ubals, Marti Vall-Mayans, Oriol Mitjà   +7 more
doaj   +1 more source

Transcription of TP0126, Treponema pallidum Putative OmpW Homolog, Is Regulated by the Length of a Homopolymeric Guanosine Repeat [PDF]

, 2015
An effective mechanism for introduction of phenotypic diversity within a bacterial population exploits changes in the length of repetitive DNA elements located within gene promoters.
Brandt, Stephanie L., Centurion-Lara, Arturo, Ciccarese, Giulia, Drago, Francesco, Giacani, Lorenzo, Iverson-Cabral, Stefanie, Ke, Wujian, Lukehart, Sheila A., Molini, Barbara J., Reid, Tara B.   +9 more
core   +1 more source

Parameters Affecting Continuous In Vitro Culture of Treponema pallidum Strains [PDF]

, 2021
The bacterium that causes syphilis, Treponema pallidum subsp. pallidum, has now been cultured in vitro continuously for periods exceeding 3 years using a system consisting of coculture with Sf1Ep rabbit epithelial cells in TpCM-2 medium and a low-oxygen ...
DeLay, Bridget D, Edmondson, Diane G, Kowis, Lindsay E, Norris, Steven J   +3 more
core   +2 more sources

Two Streptococcus pyogenes emm types and several anaerobic bacterial species are associated with idiopathic cutaneous ulcers in children after community-based mass treatment with azithromycin.

PLoS Neglected Tropical Diseases, 2022
BackgroundIn yaws-endemic areas, two-thirds of exudative cutaneous ulcers (CU) are associated with Treponema pallidum subsp. pertenue (TP) and Haemophilus ducreyi (HD); one-third are classified as idiopathic ulcers (IU).
Brad Griesenauer, Yue Xing, Katherine R Fortney, Xiang Gao, Camila González-Beiras, David E Nelson, Jie Ren, Oriol Mitjà, Qunfeng Dong, Stanley M Spinola   +9 more
doaj   +1 more source

Mapping the epidemiology of yaws in the Solomon Islands: a cluster randomized survey. [PDF]

, 2015
Yaws, a non-venereal treponemal disease, is targeted for eradication by 2020 but accurate epidemiological data to guide control programs remain sparse. The Solomon Islands reports the second highest number of cases of yaws worldwide.
Bottomley, Christian, Dalipanda, Tenneth, Mabey, David C, Marks, Michael, Pavluck, Alex, Puiahi, Elliot, Sokana, Oliver, Solomon, Anthony W, Vahi, Ventis, Zhang, Zaixing   +9 more
core   +1 more source

Outcome Predictors in Treatment of Yaws

Emerging Infectious Diseases, 2011
To estimate failure rates after treatment with benzathine penicillin and to identify determinants of failure that affected outcomes for yaws, we conducted a cohort study of 138 patients; treatment failed in 24 (17.4%).
Oriol Mitjà, Russell Hays, Anthony Ipai, David Gubaila, Francis Lelngei, Martin Kirara, Raymond Paru, Quique Bassat   +7 more
doaj   +1 more source

Syphilis [PDF]

, 2021
Syphilis, a sexually transmitted disease was first described in 15th century, is caused by Treponema pallidum subsp. pallidum and occurs worldwide. This book is a collection of chapters presenting the novel knowledge about the T.

core   +1 more source

Multiple Class I and Class II Haemophilus ducreyi Strains Cause Cutaneous Ulcers in Children on an Endemic Island [PDF]

, 2018
Background Together with Treponema pallidum subspecies pertenue, Haemophilus ducreyi is a major cause of exudative cutaneous ulcers (CUs) in children. For H.
Abecasis, Ana, Amick, Kristen M., Fortney, Kate R., Gangaiah, Dharanesh, González-Beiras, Camila, Grant, Jacob C., Humphreys, Tricia L., Mitjà, Oriol, Spinola, Stanley M.   +8 more
core   +1 more source

Sequencing-based Molecular Typing of Treponema pallidum Strains in the Czech Republic: All Identified Genotypes are Related to the Sequence of the SS14 Strain [PDF]

, 2012
A set of 415 clinical samples isolated from 294 patients suspected of having syphilis collected in the Czech Republic between 2004 and 2010 was tested for the presence of treponemal DNA.
Dastychová Eliška, Flasarová Magdalena, Kuklová Ivana, Mikalová Lenka, Pospíšilová Petra, Strnadel Radim, Vališová Zuzana, Woznicová Vladana, Zákoucká Hana, Šmajs David   +9 more
core   +1 more source