Results 31 to 40 of about 95,014 (123)

Transcriptional and immunological analysis of the putative outer membrane protein and vaccine candidate TprL of Treponema pallidum.

PLoS Neglected Tropical Diseases, 2021
BackgroundAn effective syphilis vaccine should elicit antibodies to Treponema pallidum subsp. pallidum (T. p. pallidum) surface antigens to induce pathogen clearance through opsonophagocytosis.
Austin M Haynes, Mark Fernandez, Emily Romeis, Oriol Mitjà, Kelika A Konda, Silver K Vargas, Maria Eguiluz, Carlos F Caceres, Jeffrey D Klausner, Lorenzo Giacani   +9 more
doaj   +1 more source

On the origin of trepanomatoses: A phylogenetic approach [PDF]

, 2008
Copyright @ 2007 The AuthorsBackground: Since the first recorded epidemic of syphilis in 1495, controversy has surrounded the origins of the bacterium Treponema pallidum subsp.
Robert W. George, George, Robert W., Silverman, MS, Allan Pillay, Armelagos, George J., Saunders, Nigel, Silverman, Michael S., Bolotin, S, Saunders, NJ, Saunders, Nigel J., Michael S. Silverman, Harper, KN, Steiner, Bret M., Kristin N Harper, George, RW, Paolo S. Ocampo, Armelagos, GJ, Nigel J Saunders, Paolo S Ocampo, Ocampo, PS, Pillay, Allan, Ocampo, Paolo S., Kristin N. Harper, Bret M. Steiner, Pillay, A, George J. Armelagos, Shelly Bolotin, Michael S Silverman, Nigel J. Saunders, Bolotin, Shelly, Robert W George, Harper, Kristin N., George J Armelagos, Bret M Steiner, Steiner, BM   +34 more
core   +1 more source

Female post-copulatory behavior in a group of olive baboons (Papio anubis) infected by Treponema pallidum.

PLoS ONE, 2022
Pathogens exert a profound and pervasive cost on various aspects of primate sociality and reproduction. In olive baboons (Papio anubis) at Lake Manyara National Park, Tanzania, genital skin ulcers, caused by the bacterium Treponema pallidum subsp ...
Filipa M D Paciência, Idrissa S Chuma, Iddi F Lipende, Sascha Knauf, Dietmar Zinner   +4 more
doaj   +1 more source

A cross-sectional study of 'yaws' in districts of Ghana which have previously undertaken azithromycin mass drug administration for trachoma control. [PDF]

, 2015
Yaws, caused by Treponema pallidum ssp. pertenue, is reportedly endemic in Ghana. Mass distribution of azithromycin is now the cornerstone of the WHO yaws eradication campaign.
Anthony W Solomon, Chen Cheng-Yen, Mabey, David, Chi, Kai-Hua, Agana, Nsiire, Robin L. Bailey (106607), El-Duah, Philip, Anthony W. Solomon (146301), Nsiire Agana (687465), Anthony W. Solomon, Adu-Sarkodie, Yaw, El-Duah Philip, David C. W. Mabey (168760), Pillay, Allan, Yaw Adu-Sarkodie (166893), Chi Kai-Hua, Michael Marks (276442), Kai-Hua Chi (687464), Solomon Anthony W., Marks, Michael, Robin L Bailey, Chen, Cheng-Yen, Michael Marks, Philip El-Duah (687463), Marks Michael, Rosanna Ghinai, Allan Pillay, David C. W. Mabey, Solomon, Anthony W., Cheng-Yen Chen, Bailey Robin L., Ghinai Rosanna, Bailey, Robin, Kai-Hua Chi, David C W Mabey, Agana Nsiire, Allan Pillay (39616), Yaw Adu-Sarkodie, Solomon, Anthony W, Rosanna Ghinai, Mabey David C. W., Philip El-Duah, Nsiire Agana, Pillay Allan, Bailey, Robin L, Adu-Sarkodie Yaw, Ghinai, Rosanna, Cheng-Yen Chen (687466), Mabey, David CW, Rosanna Ghinai (687462), Robin L. Bailey   +50 more
core   +1 more source

Haemophilus ducreyi DNA is detectable on the skin of asymptomatic children, flies and fomites in villages of Papua New Guinea. [PDF]

PLoS Neglected Tropical Diseases, 2017
BACKGROUND:Haemophilus ducreyi and Treponema pallidum subsp. pertenue are major causes of leg ulcers in children in Africa and the Pacific Region. We investigated the presence of DNA (PCR positivity) from these bacteria on asymptomatic people, flies, and
Wendy Houinei, Charmie Godornes, August Kapa, Sascha Knauf, Eric Q Mooring, Camila González-Beiras, Ronald Watup, Raymond Paru, Paul Advent, Sivauk Bieb, Sergi Sanz, Quique Bassat, Stanley M Spinola, Sheila A Lukehart, Oriol Mitjà   +14 more
doaj   +1 more source

Syphilis at the crossroad of phylogenetics and paleopathology. [PDF]

PLoS Neglected Tropical Diseases, 2010
The origin of syphilis is still controversial. Different research avenues explore its fascinating history. Here we employed a new integrative approach, where paleopathology and molecular analyses are combined.
Fernando Lucas de Melo, Joana Carvalho Moreira de Mello, Ana Maria Fraga, Kelly Nunes, Sabine Eggers   +4 more
doaj   +1 more source

LAMP4yaws: Treponema pallidum, Haemophilus ducreyi loop mediated isothermal amplification − protocol for a cross-sectional, observational, diagnostic accuracy study

BMJ Open, 2022
Introduction Yaws, caused by the bacterium Treponema pallidum subsp. pertenue, is a neglected tropical disease targeted for eradication by 2030. Improved diagnostics will be essential to meet this goal.
Michael Marks, Tania Crucitti, Emma Michele Harding-Esch, Daniel Arhinful, Earnest Njih Tabah, Serges Tchatchouang, Oriol Mitja, Becca Louise Handley, Camila González-Beiras, Laud Antony Basing, Kouadio Aboh Hugues, Mohammed Bakheit, Lisa Becherer, Christina Ries, Nadine Borst, Simone Lüert, Sieghard Frischmann, Tamara Haerpfer, Emelie Landmann, Ivy Amanor, Aboubacar Sylla, Mireille S Kouamé-Sina, Jean P Ndzomo-Ngono, Adingra Tano, Patrick Awondo, Solange Ngazoa Kakou, Sara Eyangoh, Kennedy Kwasi Addo, Sascha Knauf   +28 more
doaj   +1 more source

Treponema pallidum subspecies pertenue (TPE) strains analyzed in this study.

, 2023
Treponema pallidum subspecies pertenue (TPE) strains analyzed in this study.
Pavla Fedrová (16979431), Julius D. Keyyu (2697478), Sascha Knauf (111363), Klára Janečková (8655201), Simone Lueert (8929184), Darina Čejková (133588), David Šmajs (48851), Christian Roos (141269), Nikola Tom (5449088), Idrissa S. Chuma (4732341)   +9 more
core   +1 more source

First Paleogenetic Evidence of Probable Syphilis and Treponematoses Cases in the Brazilian Colonial Period

BioMed Research International, Volume 2018, Issue 1, 2018., 2018
Despite interest in the origins of syphilis, paleopathological analysis has not provided answers, and paleogenetic diagnosis remains a challenge. Even venereal syphilis has low infectivity which means there are few circulating bacteria for most of the individual’s life.
Lucélia Guedes, Ondemar Dias, Jandira Neto, Laura da Piedade Ribeiro da Silva, Sheila M. F. Mendonça de Souza, Alena Mayo Iñiguez, Hisashi Fujita   +6 more
wiley   +1 more source

Survey of Treponemal Infections in Free-Ranging and Captive Macaques, 1999–2012

Emerging Infectious Diseases, 2017
Survey results showed treponemal infection among pet macaques in Southeast Asia, a region with a high prevalence of human yaws. This finding, along with studies showing treponemal infection in nonhuman primates in Africa, should encourage a One Health ...
Amy R. Klegarth, Chigozie A. Ezeonwu, Aida Rompis, Benjamin P.Y.-H. Lee, Nantiya Aggimarangsee, Mukesh Chalise, John Cortes, M. Feeroz, Barbara J. Molini, Bess C. Godornes, Michael Marks, Michael Schillaci, Gregory Engel, Sascha Knauf, Sheila A. Lukehart, Lisa Jones-Engel   +15 more
doaj   +1 more source