Yaws: 110 Years After Castellani's Discovery of Treponema pallidum subspecies pertenue [PDF]
Yaws is a neglected infectious disease that affects mostly children and adolescents living in poor, rural communities in humid, tropical areas of Africa, southeast Asia, and the Pacific Islands.
Stamm, Lola V.
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Diagnostics for Yaws Eradication: Insights From Direct Next-Generation Sequencing of Cutaneous Strains of Treponema pallidum. [PDF]
BACKGROUND: Yaws-like chronic ulcers can be caused by Treponema pallidum subspecies pertenue, Haemophilus ducreyi, or other, still-undefined bacteria. To permit accurate evaluation of yaws elimination efforts, programmatic use of molecular diagnostics is
Anthony W Solomon +32 more
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Molecular Diagnosis of Syphilis in Brazilian Ambulatory Patients: Detection of <i>Treponema pallidum</i> subsp. <i>pallidum</i> in Serum Using Ancient DNA Protocols. [PDF]
The rising incidence of syphilis in recent decades underscores the need to improve diagnostic and control strategies. The infection caused by Treponema pallidum subsp. pallidum is commonly diagnosed using serological tests. However, these methods exhibit
Brito LSS, Passos MRL, Iñiguez AM.
europepmc +2 more sources
Burrows are places where many species cross paths and potentially exchange diseases. Primates are not known to frequent burrows. However, in the Niokolo Koba National Park (Senegal) primates entering in burrows and come potentially into contact with other species, including bats.
Cédric Vermeulen +3 more
wiley +1 more source
Multiple Alleles of Treponema pallidum Repeat Gene D in Treponema pallidum Isolates
Two new tprD alleles have been identified in Treponema pallidum : tprD2 is found in 7 of 12 T. pallidum subsp. pallidum isolates and 7
Sheila A. Lukehart +5 more
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Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 26, Issue A, Page 4A-5A, 2015.
Members of the Canadian Public Health Laboratory Network Syphilis Laboratory Task Group during Authorship (co-chairs and membership in alphabetical order) +14 more
wiley +1 more source
Outcome Predictors in Treatment of Yaws
To estimate failure rates after treatment with benzathine penicillin and to identify determinants of failure that affected outcomes for yaws, we conducted a cohort study of 138 patients; treatment failed in 24 (17.4%).
Oriol Mitjà +7 more
doaj +1 more source
BackgroundIn yaws-endemic areas, two-thirds of exudative cutaneous ulcers (CU) are associated with Treponema pallidum subsp. pertenue (TP) and Haemophilus ducreyi (HD); one-third are classified as idiopathic ulcers (IU).
Brad Griesenauer +9 more
doaj +1 more source
Coinfection of a yaws patient with two closely related Treponema pallidum subsp. pertenue strains : A rare event with potential evolutionary implications [PDF]
The etiological agent of yaws is the spirochete Treponema pallidum (TP) subsp. pertenue (TPE) and infects the children of Papua New Guinea, causing ulcerative skin lesions that impairs normal growth and development.
Medappa, Mónica +6 more
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Genetic diversity in Treponema pallidum: Implications for pathogenesis, evolution and molecular diagnostics of syphilis and yaws [PDF]
Pathogenic uncultivable treponemes, similar to syphilis-causing Treponema pallidum subspecies pallidum, include T. pallidum ssp. pertenue, T. pallidum ssp. endemicum and Treponema carateum, which cause yaws, bejel and pinta, respectively.
Weinstock, George M. +5 more
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