Results 11 to 20 of about 95,014 (123)

Molecular strain typing of the yaws pathogen, Treponema pallidum subspecies pertenue [PDF]

PLoS ONE, 2018
Yaws is a neglected tropical disease caused by the bacterium Treponema pallidum subspecies pertenue. The disease primarily affects children under 15 years of age living in low socioeconomic conditions in tropical areas.
William K Ampofo, Samantha S Katz, Kennedy Kwasi Addo   +2 more
exaly   +3 more sources

Genome Analysis of Treponema pallidum subsp. pallidum and subsp. pertenue Strains: Most of the Genetic Differences Are Localized in Six Regions

PLoS ONE, 2010
The genomes of eight treponemes including T. p. pallidum strains (Nichols, SS14, DAL-1 and Mexico A), T. p. pertenue strains (Samoa D, CDC-2 and Gauthier), and the Fribourg-Blanc isolate, were amplified in 133 overlapping amplicons, and the restriction ...
Steven J. Norris, George Weinstock, David Šmajs   +2 more
exaly   +4 more sources

No evidence for yaws infection in a small‐scale cross‐sectional serosurvey in Ghanaian monkeys

Veterinary Medicine and Science, 2023
Background Treponema pallidum (TP) is a spirochaete bacterium with subspecies that in humans cause syphilis (subsp. pallidum), bejel (subsp. endemicum) and yaws (subsp. pertenue; TPE).
Eugene Adade, Christian Roos, Idrissa Shomari Chuma, Augustina Angelina Sylverken, Sascha Knauf   +4 more
doaj   +2 more sources

Yaws Disease Caused by Treponema pallidum subspecies pertenue in Wild Chimpanzee, Guinea, 2019 [PDF]

Emerging Infectious Diseases, 2020
Yaws-like lesions are widely reported in wild African great apes, yet the causative agent has not been confirmed in affected animals. We describe yaws-like lesions in a wild chimpanzee in Guinea for which we demonstrate infection with Treponema pallidum ...
Benjamin Mubemba, Emeline Chanove, Kerstin Mätz-Rensing, Jan F. Gogarten, Ariane Düx, Kevin Merkel, Caroline Röthemeier, Andreas Sachse, Helene Rase, Tatyana Humle, Guillaume Banville, Marine Tchoubar, Sébastien Calvignac-Spencer, Christelle Colin, Fabian H. Leendertz   +14 more
doaj   +2 more sources

Widespread Treponema pallidum Infection in Nonhuman Primates, Tanzania [PDF]

Emerging Infectious Diseases, 2018
We investigated Treponema pallidum infection in 8 nonhuman primate species (289 animals) in Tanzania during 2015–2017. We used a serologic treponemal test to detect antibodies against the bacterium.
Idrissa S. Chuma, Emmanuel K. Batamuzi, D. Anthony Collins, Robert D. Fyumagwa, Luisa K. Hallmaier-Wacker, Rudovick R. Kazwala, Julius D. Keyyu, Inyasi A. Lejora, Iddi F. Lipende, Simone Lüert, Filipa M.D. Paciência, Alexander Piel, Fiona A. Stewart, Dietmar Zinner, Christian Roos, Sascha Knauf   +15 more
doaj   +7 more sources

The etiology of exudative cutaneous ulcers in a yaws-endemic community prior to receipt of antimicrobials is similar to that found in communities after mass treatment with azithromycin [PDF]

mSphere
Mass drug administration (MDA) of azithromycin (AZ) and case finding and treatment of children with cutaneous ulcers (CUs) have been trialed as strategies to eliminate yaws. Metagenomic sequencing of CU swabs obtained from children 3 to 4 years after the
Julie A. Brothwell, Evelyn Toh, Yue Xing, Qunfeng Dong, Linda H. Xu, Lorenzo Giacani, Camila G. Beiras, Oriol Mitjà, Xiang Gao, Stanley M. Spinola   +9 more
doaj   +2 more sources

Absence of human yaws and detection of Haemophilus ducreyi in skin ulcers of school children near wildlife protected areas in Tanzania. [PDF]

PLoS Neglected Tropical Diseases
BackgroundTo support Tanzania's quest for certification free of human yaws, we tested children with skin ulcers for yaws infection living near areas of reported nonhuman primate (NHP) infection with Treponema pallidum subsp. pertenue (TPE).
Clara Clavery Lubinza, Alina Johanna Anton, Simone Lueert, Eugene Adade, Idrissa Shomari Chuma, Augustina Angelina Sylverken, David Šmajs, Sayoki Godfrey Mrinde Mfinanga, Christian Roos, Sascha Knauf   +9 more
doaj   +2 more sources

Assessment of the role of Haemophilus ducreyi coinfection on outcomes of Yaws treatment in the southwestern part of Ghana. [PDF]

PLoS Neglected Tropical Diseases
BackgroundYaws, caused by Treponema pallidum subsp. pertenue (TP) is targeted for eradication by 2030 under the World Health Organization's (WHO) initiative, which relies on mass drug administration (MDA) of azithromycin.
Abigail Agbanyo, Michael Ntiamoah Oppong, Dzifa Kofi Ahiatrogah, Ruth Dede Tuwor, Clement Tettey, Joseph Azabire, Owusu Boakye Yiadom, Dennis Odai Laryea, Alex Owusu-Ofori, Richard Odame Phillips, Yaw Ampem Amoako   +10 more
doaj   +2 more sources

Geographically structured genomic diversity of non-human primate-infecting Treponema pallidum subsp. pertenue. [PDF]

Microb Genom, 2020
Many non-human primate species in sub-Saharan Africa are infected with Treponema pallidum subsp. pertenue, the bacterium causing yaws in humans. In humans, yaws is often characterized by lesions of the extremities and face, while T.
Mubemba B, Gogarten JF, Schuenemann VJ, Düx A, Lang A, Nowak K, Pléh K, Reiter E, Ulrich M, Agbor A, Brazzola G, Deschner T, Dieguez P, Granjon AC, Jones S, Junker J, Wessling E, Arandjelovic M, Kuehl H, Wittig RM, Leendertz FH, Calvignac-Spencer S.   +21 more
europepmc   +2 more sources

Yaws in Africa: Past, Present and Future [PDF]

Diseases
Background: Yaws is an infectious, neglected tropical disease that affects the skin of many children and adolescents who live in poor, rural, low-income communities in humid, tropical areas of Africa, Southeast Asia, and the Pacific Islands.
Ezekiel K. Vicar, Shirley V. Simpson, Gloria I. Mensah, Kennedy K. Addo, Eric S. Donkor   +4 more
doaj   +2 more sources