Development of a Multilocus Sequence Typing (MLST) scheme for Treponema pallidum subsp. pertenue: Application to yaws in Lihir Island, Papua New Guinea [PDF]
PLoS Neglected Tropical Diseases, 2017 BackgroundYaws is a neglected tropical disease, caused by Treponema pallidum subsp. pertenue. The disease causes chronic lesions, primarily in young children living in remote villages in tropical climates.
Sheila A Lukehart +2 more
exaly +3 more sources
Complete genome sequences of two strains of Treponema pallidum subsp. pertenue from Indonesia: Modular structure of several treponemal genes [PDF]
PLoS Neglected Tropical Diseases, 2018 BACKGROUND:Treponema pallidum subsp. pertenue (TPE) is the causative agent of yaws, a multistage disease endemic in tropical regions in Africa, Asia, Oceania, and South America.
Sascha Knauf, Jan Oppelt, David Šmajs
exaly +3 more sources
Complete genome sequences of two strains of Treponema pallidum subsp. pertenue from Ghana, Africa: Identical genome sequences in samples isolated more than 7 years apart [PDF]
PLoS Neglected Tropical Diseases, 2017 BackgroundTreponema pallidum subsp. pertenue (TPE) is the causative agent of yaws, a multi-stage disease, endemic in tropical regions of Africa, Asia, Oceania, and South America.
Ivan Rychlik +2 more
exaly +4 more sources
Nonhuman primates across sub-Saharan Africa are infected with the yaws bacterium Treponema pallidum subsp. pertenue [PDF]
Emerging Microbes and Infections, 2018 Sascha Knauf +2 more
exaly +4 more sources
The genomes of the yaws bacterium, Treponema pallidum subsp. pertenue, of nonhuman primate and human origin are not genomically distinct. [PDF]
PLoS Neglected Tropical Diseases, 2023 BackgroundTreponema pallidum subsp. pertenue (TPE) is the causative agent of human yaws. Yaws is currently reported in 13 endemic countries in Africa, southern Asia, and the Pacific region.
Klára Janečková +9 more
doaj +2 more sources
Strain diversity of Treponema pallidum subsp. pertenue suggests rare interspecies transmission in African nonhuman primates [PDF]
Scientific Reports, 2019 In our most recent study, we found that in Tanzania infection with Treponema pallidum (TP) subsp. pertenue (TPE) is present in four different monkey species.
Idrissa S. Chuma +16 more
doaj +2 more sources
Molecular and serological evidence of systemic Treponema pallidum infection in wild western chimpanzees [PDF]
iScienceSummary: Human treponematoses are chronic diseases caused by closely related Treponema species. Increasing evidence of yaws-like Treponema pallidum subsp.
Clément Labarrere +7 more
doaj +2 more sources
PLoS Neglected Tropical Diseases, 2017 BackgroundTreponema pallidum subsp. endemicum (TEN) is the causative agent of endemic syphilis (bejel). An unusual human TEN 11q/j isolate was obtained from a syphilis-like primary genital lesion from a patient that returned to France from Pakistan ...
Jan Oppelt +2 more
exaly +2 more sources
Mapping the distribution of yaws and Haemophilus ducreyi in the western north region of Ghana [PDF]
BMC Infectious DiseasesBackground Treponema pallidum subspecies pertenue and Haemophilus ducreyi cause skin ulcers in impoverished communities. Historical serologic records from Ghana focus on T. pallidum, omitting potential H. ducreyi cases. The objective of this study was to
Shirley Victoria Simpson +11 more
doaj +2 more sources
Topical treatment with gallium maltolate reduces Treponema pallidum subsp. pertenue burden in primary experimental lesions in a rabbit model of yaws. [PDF]
PLoS Neglected Tropical Diseases, 2019 BackgroundGallium is a semi-metallic element known since the 1930s to have antimicrobial activity. This activity stems primarily from gallium's ability to mimic trivalent iron and disrupt specific Fe(III)-dependent pathways, particularly DNA synthesis ...
Lorenzo Giacani +10 more
doaj +2 more sources