Abstract Objectives The eradication of yaws, a childhood disease caused by Treponema pallidum subsp. pertenue, is constrained by the lack of rapid, accurate diagnosis.
openaire +1 more source
The human host-pathogen interaction in the light of ancient genomics revolution [PDF]
The aim of this thesis is to analyse the changes that have occurred in the immune system of the human host after key moments, such as pandemic and epidemic events, by comparing the variants of immunity genes before and after such events, and to study one
Barquera, Rodrigo
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Advancing yaws diagnosis through point of care diagnostics: A peptide-centric design approach
Yaws, a chronic Neglected Tropical Disease (NTD) caused by Treponema pallidum subsp. pertenue, causes severe skin ulcers and bone damage if untreated, primarily affecting marginalized communities.
Elijah Kolawole Oladipo +9 more
doaj +1 more source
Advancing the understanding of treponemal disease in the past and present [PDF]
Syphilis was perceived to be a new disease in Europe in the late 15th century, igniting a debate about its origin that continues today in anthropological, historical, and medical circles.
Akrawi F. +117 more
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Re-emergence of yaws after single mass azithromycin treatment followed by targeted treatment: a longitudinal study [PDF]
Background: Yaws is a substantial cause of chronic disfiguring ulcers in children in at least 14 countries in the tropics. WHO's newly adopted strategy for yaws eradication uses a single round of mass azithromycin treatment followed by targeted treatment
Abel, Haina +12 more
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Yaws re-emergence and bacterial drug resistance selection after mass administration of azithromycin: a genomic epidemiology investigation. [PDF]
BACKGROUND: In a longitudinal study assessing the WHO strategy for yaws eradication using mass azithromycin treatment, we observed resurgence of yaws cases with dominance of a single JG8 sequence type and emergence of azithromycin-resistant Treponema ...
Beale, Mathew A +15 more
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The origin of syphilis-still controversial? [PDF]
Syphilis is a sexually transmitted disease caused by spiral-shaped bacterium, Treponema pallidum The disease has been known under many names during history, and has had a prominent role in history and literature for the last several hundred years.
Marinković Živorad, Đukić Slobodanka
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Tomographic reconstruction of treponemal cytoplasmic filaments reveals novel bridging and anchoring components [PDF]
An understanding of the involvement of bacterial cytoplasmic filaments in cell division requires the elucidation of the structural organization of those filamentous structures.
Barnard, Rita M. +5 more
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Yaws, a prevalent tropical disease primarily affecting children, is characterized by the presence of erythematous lesions predominantly found in the lower limb. Through a comprehensive multi-locus analysis of 255 fully typed clincal isolates, it was discovered that three allelic profiles (APs) namely J11, S22 and T13 are present.
Medappa Monica +4 more
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Тропические невенерические трепонематозы (клиническая лекция) [PDF]
Наведено дані про етіологію, патогенез, клінічні прояви невенеричних трепонематозів. Розглянуто принципи діагностики основних невенеричних трепонематозів (пінти, фрамбезії, беджелю). Викладено новітні дані щодо їх лікування.
Веретельник, А.В.
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