Results 51 to 60 of about 2,492 (156)

Novel and emerging antimicrobial strategies in the management of oral infections

Periodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source

Interaction of Treponema pallidum, the syphilis spirochete, with human platelets.

PLoS ONE, 2019
Extracellular bacteria that spread via the vasculature employ invasive mechanisms that mirror those of metastatic tumor cells, including intravasation into the bloodstream and survival during hematogenous dissemination, arrestation despite blood flow ...
Brigette Church, Erika Wall, John R Webb, Caroline E Cameron   +3 more
doaj   +1 more source

Distribution of Treponema Species in Active Digital Dermatitis Lesions and Non-Lesional Skin of Dairy Cattle

Microbiology Research
This study examined the prevalence, distribution, and detection methods linked to Treponema species associated with active bovine digital dermatitis (BDD) in dairy cattle. Tissue, surface swabs, interdigital space swabs, and faecal samples were collected
Simona Mekková, Miriam Sondorová, Natália Šurín Hudáková, Viera Karaffová, Marián Maďar, Pavel Gomulec, Pavol Mudroň   +6 more
doaj   +1 more source

Epidemiological Dynamics of a Visually Apparent Disease: Camera Trapping and Machine‐Learning Applied to Rumpwear in the Common Brushtail Possum

Integrative Zoology, Volume 21, Issue 1, Page 116-128, January 2026.
Visually apparent diseases are valuable for investigating and monitoring the occurrence and prevalence of pathogens in wildlife populations through passive monitoring methods like camera trapping. Rumpwear is characterized by visible signs of hair breakage and damage on the lumbosacral region of common brushtail possums.
Elise M. Ringwaldt, Jessie C. Buettel, Scott Carver, Barry W. Brook   +3 more
wiley   +1 more source

In-depth sequence analysis of highly-conserved pyrH gene to study distributions of oral treponemes in periodontal disease versus health

Journal of Oral Microbiology, 2017
Background: More than 75 species/species-level phylotypes of oral treponeme bacteria inhabit the oral cavity. However, their respective genomic compositions and clinical distributions remain poorly understood.
Rory M. Watt
doaj   +1 more source

Land use and soil characteristics are associated with increased risk of treponeme‐associated hoof disease in elk

Ecosphere, Volume 16, Issue 12, December 2025.
Abstract Environments can shape the occurrence and extent of disease outbreaks in wildlife. We studied the effects of environmental features on the occurrence of treponeme‐associated hoof disease (TAHD), an emerging infectious disease of free‐ranging elk (Cervus canadensis), in southwestern Washington, USA.
Steven N. Winter, Glen A. Sargeant, Margaret A. Wild, Erin Clancey, Kathryn P. Huyvaert, Kyle Garrison, Pilar Fernandez   +6 more
wiley   +1 more source

Pharmacokinetics and Safety of Intramuscular Injectable Benzathine Penicillin G in Japanese Healthy Participants

The Journal of Clinical Pharmacology, Volume 64, Issue 10, Page 1259-1266, October 2024.
Abstract An intramuscular (IM) suspension of benzathine penicillin G (BPG) has been used as first‐line therapy for the treatment of syphilis worldwide since its approval in the 1950s. However, there are limited reports about the pharmacokinetics of BPG.
Yinhua Li, Akifumi Okayama, Toshiaki Hagi, Chieko Muto, Susan Raber, Masahito Nagashima   +5 more
wiley   +1 more source

Whole genome sequence of the Treponema pallidum subsp. endemicum strain Iraq B: A subpopulation of bejel treponemes contains full-length tprF and tprG genes similar to those present in T. p. subsp. pertenue strains.

PLoS ONE, 2020
Treponema pallidum subsp. endemicum (TEN) is the causative agent of endemic syphilis (bejel). Until now, only a single TEN strain, Bosnia A, has been completely sequenced.
Lenka Mikalová, Klára Janečková, Markéta Nováková, Michal Strouhal, Darina Čejková, Kristin N Harper, David Šmajs   +6 more
doaj   +1 more source

A public database for the new MLST scheme for Treponema pallidum subsp. pallidum: surveillance and epidemiology of the causative agent of syphilis [PDF]

PeerJ, 2019
Treponema pallidum subsp. pallidum is the causative agent of syphilis, a sexually transmitted disease with worldwide prevalence. Several different molecular typing schemes are currently available for this pathogen. To enable population biology studies of
Linda Grillova, Keith Jolley, David Šmajs, Mathieu Picardeau   +3 more
doaj   +2 more sources

Characterization of c‐di‐AMP signaling in the periodontal pathobiont, Treponema denticola

Molecular Oral Microbiology, Volume 39, Issue 5, Page 354-367, October 2024.
Abstract Pathobionts associated with periodontitis, such as Treponema denticola, must possess numerous sensory transduction systems to adapt to the highly dynamic subgingival environment. To date, the signaling pathways utilized by T. denticola to rapidly sense and respond to environmental stimuli are mainly unknown.
Aidan D. Moylan, Dhara T. Patel, Claire O'Brien, Edward J. A. Schuler, Annie N. Hinson, Richard T. Marconi, Daniel P. Miller   +6 more
wiley   +1 more source