, 1998 Acneiform dermatoses are follicular eruptions. The initial lesion is inflammatory, usually a papule or pustule. Comedones are later secondary lesions, a sequel to encapsulation and healing of the primary abscess.
Jansen, Thomas, Plewig, G.
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Nitric Oxide-Releasing Nanoparticles Prevent Propionibacterium acnes-Induced Inflammation by Both Clearing the Organism and Inhibiting Microbial Stimulation of the Innate Immune Response. [PDF]
, 2015 Propionibacterium acnes induction of IL-1 cytokines through the NLRP3 (NLR, nucleotide oligomerization domain-like receptor) inflammasome was recently highlighted as a dominant etiological factor for acne vulgaris.
Adler, Brandon L +16 more
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Vesicular systems for delivering conventional small organic molecules and larger macromolecules to and through human skin [PDF]
, 2009 The history of using vesicular systems for drug delivery to and through skin started nearly three decades ago with a study utilizing phospholipid liposomes to improve skin deposition and reduce systemic effects of triamcinolone acetonide.
El Maghraby, Gamal M. +1 more
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Solid Lipid Nanoparticles: A Potential Approach for Dermal Drug Delivery [PDF]
, 2014 Solid lipid nanoparticles (SLNs) have attracted increasing attention during recent years. Due to their unique size dependent properties, lipid nanoparticles offer possibilities to develop new therapeutics.
Conway, Barbara R, Kakadia, Pratibha G.
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In vitro comparison of simple tretinoin-cream and cream loaded with tretinoin-SLN [PDF]
journal of Pharmaceutical Technology and Drug Research, 2013 Abstract Background: Tretinoin is one of the commonly used medications in treatment of skin aging symptoms. However, its topical application leads to local irritation at the application site which often limits ...
Effat Sadat Farboud +2 more
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Effects of Topically Applied Acitretin in Reconstructed Human Epidermis and the Rhino Mouse [PDF]
, 2008 Oral acitretin is currently indicated for the treatment of severe psoriasis in adults, but its use is limited by systemic side effects and teratogenicity. Topical administration of acitretin may lessen the risk of systemic toxicity while increasing local
Chern, Wendy H. +4 more
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Drugs in R & D, 2005 Connetics Corporation (USA) has licensed a first-in-class, dual-action 1% clindamycin/0.025% tretinoin aqueous gel [Clindamycin phosphate/tretinoin gel, Velac, Velac Gel] from Yamanouchi Europe BV. The product combines the anti-inflammatory and antibacterial properties of clindamycin with the beneficial effects of tretinoin [all-trans-retinoic acid ...
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Analysis of common oral and topical dermatologic medication price variation by source [PDF]
, 2020 Online coupon retailers and pharmacies are popular sites that patients can access discounted medications when compared to cash prices. These sources are especially important for those patients without insurance.
Boyko, Alexander, Smith, Gideon P
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A review of tazarotene in the treatment of photodamaged skin [PDF]
, 2008 Stephanie Ogden1, Miny Samuel2, Christopher EM Griffiths11Dermatology Centre, University of Manchester, Hope Hospital, Salford Manchester, M6 8HD, UK; 2RTI-Health Solutions, Williams House, Manchester Science Park, Lloyd Street North, Manchester M15 6SE,
Chambers, A. J. +8 more
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Effects of Dermatitis, Stripping, and Steroids on The Morphology of Corneocytes. a New Bioessay [PDF]
, 1977 This study was designed to investigate the effects of increased or decreased epidermal turnover on the morphology of human corneocytes. The desquamating portion of the stratum corneum was sampled with the detergent scrub technique using Triton X-100. The
Hölzle, Erhard., Plewig, Gerd.
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