Terapi Topikal Tretinoin 0,025% + Zinc Oral Dibandingkan Topikal Nicotinamide 4% + Zinc Oral Pada Akne Vulgaris [PDF]
Latar Belakang : Akne vulgaris merupakan penyakit kulit yang umum terjadi pada remaja dan dewasa. Terapi topikal untuk akne dapat digunakan sebagai monoterapi maupun kombinasi dengan terapi sistemik.
Usodo, G. P. (Gloria)+1 more
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Isotretinoin Revisited: Pluripotent Effects on Human Sebaceous Gland Cells [PDF]
Nelson et al. confirmed the previously described antiproliferative effect of isotretinoin on human sebocytes. They attributed a portion of this decrease to cell cycle arrest and detected sebocyte apoptosis, which was not recapitulated by alitretinoin or ...
Zouboulis, Christos C.
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ABSTRACT Background Keloid treatment remains challenging due to high recurrence rates, particularly in patients with higher phototypes. This study aimed to assess the resolution, patient satisfaction, and recurrence rates in 79 keloids treated with a sequential non‐surgical protocol combining long‐term occlusion with hydrocolloid dressings, monthly ...
Marina Patrus Ananias de Souza Brandão+6 more
wiley +1 more source
International expert consensus recommendations for the use of dermocosmetics in acne
Abstract Background A wide variety of dermocosmetics (products with both active skincare and cosmetic activity) are available for the management of acne vulgaris. These products are important because they may be the first line of approach for patients desiring to self‐treat and they can also have beneficial effects—reducing lesion counts and improving ...
Diane Thiboutot+7 more
wiley +1 more source
Severe osteoarticular involvement in isotretinoin-triggered acne fulminans: two cases successfully treated with anakinra. [PDF]
Acne fulminans (AF) is a severe form of inflammatory and ulcerated acne associated with fever, malaise, joint swellings and polyarthralgia.1 Osteoarticular lesions are often described and can be radiologically indistinguishable from those observed in
Barbareschi+9 more
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Low‐dose isotretinoin for the management of rosacea: A systematic review and meta‐analysis
Isotretinoin, a vitamin A derivative primarily known for treating acne vulgaris, has been investigated for rosacea despite its off‐label use. This systematic review and meta‐analysis of 16 studies involving 1445 patients examined low‐dose isotretinoin (defined as ≤0.5 mg/kg/day) for the four main types of rosacea. This study found significant reduction
Aliyah King+3 more
wiley +1 more source
Role of topical tretinoin in melanoma and dysplastic nevi. [PDF]
The retinoids have been investigated extensively as chemopreventive and therapeutic agents in a variety of neoplasms. They have been shown to inhibit the proliferation of transformed cell lines in vitro and transplanted tumors in vivo. In cultured murine
Edwards, L, Levine, NS, Meyskens, FL
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Differential effects of caffeine on hair shaft elongation, matrix and outer root sheath keratinocyte proliferation, and TGF-beta2-/IGF-1-mediated regulation of hair cycle in male and female human hair follicles in vitro. [PDF]
BACKGROUND: Caffeine reportedly counteracts the suppression of hair shaft production by testosterone in organ-cultured male human hair follicles (HFs).
Bíró, Tamás+4 more
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Acne and the cutaneous microbiome: A systematic review of mechanisms and implications for treatments
Impact of Acne Therapies on the Skin Microbiome: This graphical abstract illustrates how various acne treatments affect the cutaneous microbiome, particularly focusing on Cutibacterium acnes and overall microbial diversity. Common treatments like doxycycline and benzoyl peroxide generally decrease C. acnes and reduce alpha diversity, while isotretinoin
Alicia Podwojniak+7 more
wiley +1 more source
Cosmeceuticals in the Pediatric Population Part I: A Review of Risks and Available Evidence
ABSTRACT The rise in the use of cosmeceuticals among children and adolescents has created a new challenge for dermatologists, who are confronted with the task of advising young patients on the risks that these products can carry and the often questionable efficacy of these products.
Gabrielle Keller Goff, Sarah L. Stein
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