Results 61 to 70 of about 15,648 (249)

Clinical Features and Current Therapeutic Approaches to Monilethrix: A Systematic Review

Pediatric Dermatology, EarlyView.
ABSTRACT Monilethrix is a rare congenital hair disorder characterized by fragile, beaded hair shafts due to mutations in various keratin or desmoglein 4 genes. A systematic review of 24 studies (16 pediatric only, 3 mixed adult and pediatric, 3 adult only, and 2 unspecified) evaluating various treatment modalities identified topical and oral minoxidil ...
Adam C. Yu, Dana Koroluk, Fatmah Alzahrani   +2 more
wiley   +1 more source

Preparation and Evaluation of Tretinoin Microemulsion Based on Pseudo-Ternary Phase Diagram [PDF]

, 2012
Purpose: The aim of the present research was to formulate a transparent microemolsion as a topical delivery system for tretinoin for the treatment of acne.
Anayatollah Salimi, Eskandar Moghimipour, Fatemeh Leis   +2 more
core  

Glucocorticoids for human skin: New aspects of the mechanism of action [PDF]

, 2005
Topical glucocorticoids have always been considered first-line drugs for inflammatory diseases of the skin and bronchial system. Applied systemically, glucocorticoids are used for severe inflammatory and immunological diseases and the inhibition of ...
Ahmed, M., Holtje, H. D., Kleuser, B., Korting, Hans Christian, Schäfer-Korting, Monika   +4 more
core   +1 more source

Outcomes of a Non‐Surgical Combination Therapy for Keloids in Skin of Color Patients: A 10‐Year Follow‐Up Study

International Journal of Dermatology, Volume 64, Issue 8, Page 1434-1440, August 2025.
ABSTRACT Background Keloid treatment remains challenging due to high recurrence rates, particularly in patients with higher phototypes. This study aimed to assess the resolution, patient satisfaction, and recurrence rates in 79 keloids treated with a sequential non‐surgical protocol combining long‐term occlusion with hydrocolloid dressings, monthly ...
Marina Patrus Ananias de Souza Brandão, Carolina Fernandes Otoni Vieira, Daniel Brasil Braga Rocha, Márcio Roberto Silva, Jussara Aparecida da Silva, Michael H. Gold, Gisele Viana de Oliveira   +6 more
wiley   +1 more source

Role of topical tretinoin in melanoma and dysplastic nevi. [PDF]

, 1986
The retinoids have been investigated extensively as chemopreventive and therapeutic agents in a variety of neoplasms. They have been shown to inhibit the proliferation of transformed cell lines in vitro and transplanted tumors in vivo. In cultured murine
Edwards, L, Levine, NS, Meyskens, FL
core  

Synergistic drug combinations from electronic health records and gene expression. [PDF]

, 2016
ObjectiveUsing electronic health records (EHRs) and biomolecular data, we sought to discover drug pairs with synergistic repurposing potential. EHRs provide real-world treatment and outcome patterns, while complementary biomolecular data, including ...
Chen, William, Daugherty, Aaron C, Desai, Manisha, Farrington, Carl, Gomez, Scarlett L, Hastie, Trevor, Kenkare, Pragati, Kurian, Allison W, Lim, Michael, Low, Yen S, Mathur, Maya, Radin, Andrew A, Schroeder, Elizabeth A, Seto, Tina, Shah, Nigam H, Sirota, Marina, Sledge, George W, Thompson, Caroline A, Weber, Susan, Yu, Peter P   +19 more
core   +2 more sources

A Case Report of Generalization of Localized Actinic Granuloma, an Unusual Diffuse Presentation Not Responding to Tofacitinib

Clinical Case Reports, Volume 13, Issue 7, July 2025.
ABSTRACT Actinic granuloma (AG), a rare and idiopathic skin condition primarily affecting middle‐aged and elderly individuals, is known for its persistent, asymptomatic annular plaques appearing on sun‐exposed areas. This report details the case of a 48‐year‐old diabetic male farmer with a rare presentation of generalized AG. The patient's lesions were
Saman Al‐Zahawi, Alireza Ghanadan, Fatemeh Saberi   +2 more
wiley   +1 more source

Development and validation of stability indicating HPLC–PDA method for the simultaneous determination of benzoyl peroxide and tretinoin in topical dosage form

Future Journal of Pharmaceutical Sciences, 2023
Background Acne vulgaris is a very dangerous skin disease leads to psychological disorders. Benzoyl peroxide and tretinoin in combination with topical dosage are used to improve the appearance of acne-prone skin.
Muhammad Usman, Tauqeer Abbas
doaj   +1 more source

Trends and Developments in Vulvar Lichen Sclerosus Research

Health Science Reports, Volume 8, Issue 7, July 2025.
ABSTRACT Background Despite the prevalence of vulvar lichen sclerosus (VLS) as a chronic skin disease in clinical settings, there is a notable absence of a comprehensive bibliometric analysis summarizing the existing literature on this topic. The aim of this study is to offer clinicians, researchers, and other interested parties an up‐to‐date overview ...
Fan‐Rong He, Yan‐Rui Lin, Yu‐Hua Wen, Jin‐He Deng   +3 more
wiley   +1 more source

Announcing the Biomedical Data Translator: Initial Public Release

Clinical and Translational Science, Volume 18, Issue 7, July 2025.
ABSTRACT The growing availability of biomedical data offers vast potential to improve human health, but the complexity and lack of integration of these datasets often limit their utility. To address this, the Biomedical Data Translator Consortium has developed an open‐source knowledge graph–based system—Translator—designed to integrate, harmonize, and ...
Karamarie Fecho, Gwênlyn Glusman, Sergio E. Baranzini, Chris Bizon, Matthew Brush, William Byrd, Lawrence Chung, Andrew Crouse, Eric Deutsch, Michel Dumontier, Aleksandra Foksinska, Jennifer Hadlock, Kaiwen He, Sui Huang, Robert Hubal, Gregory M. Hyde, Sharat Israni, Kelyne Kenmogne, David Koslicki, Jana Dorfman Marcette, Ewy A. Mathe, Abrar Mesbah, Sierra A. T. Moxon, Christopher J. Mungall, John Osborne, Carrie Pasfield, Guangrong Qin, Stephen A. Ramsey, Justin Reese, Jared C. Roach, Reese Rose, Karthik Soman, Andrew I. Su, Casey Ta, Gaurav Vaidya, Rosina Weber, Qi Wei, Mark Williams, Chunlei Wu, Colleen Xu, Chase Yakaboski, The Biomedical Data Translator Consortium, Michel Arab, Shervin Abdollahi, Nichollette Acosta, Ayushi Agrawal, Stanley Ahalt, Nada Amin, Michael Bada, Krish Balar, Jim Balhoff, William Baumgartner, Jon‐Michael Beasley, Emily Blake, Namdi Brandon, Richard Bruskiewich, Noel Burtt, Jackson Callaghan, Terese Camp, Marco Alvarado Cano, Kathleen Carter, Remzi Celebi, Cheng‐Han Chung, Larry Chung, Maria Costanzo, Margot Cousin, Tim Curry, Vlado Dancik, Jennifer Dougherty, Marc Duby, Stephen Edwards, Joe Farris, Nate Fehrmann, Marta Figueiral, Jason Flannick, Charlie Fox, Amy Glen, Prateek Goel, Skye Goetz, Joseph Gormley, Perry Haaland, Kristina Hanspers, Nomi Harris, Jeff Henrickson, Anthony Hickey, Eugene Hinderer, Maureen Hoatlin, Tursynay Issabekova, Rhea Karty, Yaphet Kebede, Keum Joo Kim, Simon King, Eric Klee, Michael R. Knowles, Ryan Koesterer, Daniel Korn, Ashok Krishnamurthy, Laura Lambert, Margaret W. Leigh, Jason Lin, Max Lupey, Chunyu Ma, Andrew Magis, Mallika Mainali, Meisha Mandal, Luis Mendoza, Matthew Might, Evan Morris, Kenny Morton, Sandrine Muller, Kamileh Narsinh, Olawumi Olasunkanmi, Deepak Panwar, Michael Patton, David B. Peden, Amber Peters, Alexander Pico, Filippo Pinto e Vairo, Nishad Prakash, Guthrie Price, Sundareswar Pullela, Anthony Ragazzi, Navya Ramakrishnan, Jason Reilly, Everaldo Rodolpho, Greg Rosenblatt, Irit Rubin, Rayn Sakaguchi, Eugene Santos, Ava Schaak, Johnathan Schaff, Kevin Schaper, Shepherd Schurman, Brett Smith, David Smith, Sarah Stemann, Michael Strasser, Harsha Sureshbabu, Mohsen Taheri, Alexander Tropsha, Sarah Tyndall, Adam Viola, Kevin Vizhalil, Madison Walker, Chen Wang, Max Wang, Braiden Wardon, Paul B. Watkins, Ximing Wen, Chunhua Weng, Elizabeth White, Stephanie Won, Erica Wood, Braiden Worden, Yao Xiao, Rena Yang, Hong Yi, Qian Zhu, Tom Zisk   +158 more
wiley   +1 more source