Results 221 to 230 of about 13,020 (271)

Transfer RNA-derived small RNAs in cardiovascular diseases: Progress and perspectives. [PDF]

Noncoding RNA Res
Wen X, Wang S, Chen H, Zhang H, Ji Y.
europepmc   +1 more source

Small non-coding RNA profiling reveals inflammatory and mitochondrial related changes in aging β-cells and islet macrophages

Guay C, Perrard J, Mangano E, Menoud V, Aiello E, Fignani D, Dotta F, Bonner-Weir S, Sebastiani G, Aguayo-Mazzucato C, Cosentino C, Regazzi R.   +11 more
europepmc   +1 more source

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tRFs: miRNAs in disguise

Gene, 2016
tRFs and tiRNAs are two new classes of regulatory non-coding small RNAs that are derived from the cleavage of pre-existing tRNAs. tRFs are 18-22 nt long and are classified into the tRF-5, tRF-3, and tRF-1 series. Here, we discuss in detail the regulatory roles of tRFs in translation, viral infections, and carcinogenesis.
Rie Tsutsumi, Thejaswini Venkaṭesh
exaly   +4 more sources

Role of non-coding RNAs against salinity stress in Oryza species: Strategies and challenges in analyzing miRNAs, tRFs and circRNAs

International Journal of Biological Macromolecules, 2023
Salinity is an imbalanced concentration of mineral salts in the soil or water that causes yield loss in salt-sensitive crops. Rice plant is vulnerable to soil salinity stress at seedling and reproductive stages.
Tapan Mondal
exaly   +2 more sources

Serum tRNA‐derived fragments (tRFs) as potential candidates for diagnosis of nontriple negative breast cancer

Journal of Cellular Physiology, 2020
Breast cancer has become the most common cancer in women, and nontriple negative breast cancer (non‐TNBC) accounts for 80–90% of all invasive breast cancers.
Mingjie Zheng, Hui Xie, Yue Huang
exaly   +2 more sources

Extensive profiling of the expressions of tRNAs and tRNA-derived fragments (tRFs) reveals the complexities of tRNA and tRF populations in plants

Science China Life Sciences, 2021
Evidence is emerging that tRNA-derived fragments (tRFs) are regulatory molecules. Studies of tRFs in plants have been based on conventional small RNA sequencing, and focused on profiling of tRF-5 and tRF-3 species. A more comprehensive and quantitative analysis of the entire tRF population is highly necessary.
Xuan Ma, Chunyan Liu, Xiaocong Kong, Jing Liu, Siju Zhang, Shanshan Liang, W. Luan, Xiaofeng Cao   +7 more
semanticscholar   +3 more sources

A tRF nucleator for Nucleolin in cancer metastasis

Molecular Cell, 2022
In this issue of Molecular Cell, Liu et al. (2022) report that 5'-tRFCys, a stress-induced transfer RNA-derived RNA fragment (tRF) derived from the 5' halves of cysteine tRNAs, regulates post-transcriptional gene expression, enabling the survival and lung metastasis formation of breast cancers.
Yichen, Xu, Davide, Ruggero
openaire   +2 more sources

tRFs as Potential Exosome tRNA-Derived Fragment Biomarkers for Gastric Carcinoma.

Clinical Laboratory, 2020
BACKGROUND Gastric Carcinoma (GC) is one of the common diseases induced by the interaction of genes and environment. Exosomes are potential markers for several health problems, which contain lipids, proteins, long non-coding RNAs, microRNAs (miRNAs), and
Caifeng Lin, Linwen Zheng, R. Huang, Guohua Yang, Juyin Chen, Houqiang Li   +5 more
semanticscholar   +1 more source

Mucosal immunity and tRNA, tRF, and tiRNA

Journal of Molecular Medicine, 2020
Mucosal immunity has crucial roles in human diseases such as respiratory tract infection, inflammatory bowel diseases (IBD), and colorectal cancer (CRC). Recent studies suggest that the mononuclear phagocyte system, cancer cells, bacteria, and viruses induce the mucosal immune reaction by various pathways, and can be major factors in the pathogenesis ...
Yueying Chen, Jun Shen
openaire   +2 more sources