Results 151 to 160 of about 23,921 (208)
Summary Background The diagnosis and management of pituitary pars intermedia dysfunction (PPID) in horses includes evaluating abnormal plasma concentrations of adrenocorticotrophic hormone (ACTH). Treatment commonly includes the oral dopamine agonist pergolide mesylate, which suppresses the pathologic overproduction of ACTH.
A. Bracken +5 more
wiley +1 more source
TGF‐β signaling regulates extracellular vesicle (EV) release in cancer cells by modulating the expression and activity of genes associated with EV biogenesis. The TGF‐β‐induced upregulation of RAB4A expression facilitates fast endosomal recycling, a process that limits the fusion of multivesicular bodies with the plasma membrane and EV secretion. Hence,
Dorival Mendes Rodrigues‐Junior +5 more
wiley +1 more source
ABSTRACT Background In Kenya, influenza and other respiratory viruses circulate year‐round. The Ministry of Health monitors severe acute respiratory infections (SARI), including influenza‐associated hospitalizations, through a sentinel surveillance network. We developed intensity thresholds (ITs) to assess seasonal severity based on respiratory illness‐
Elizabeth B. White +11 more
wiley +1 more source
Marine flatworms as windows into the evolution of bilaterian neuropeptide signalling
Abstract The evolutionary origin(s) of neuropeptide signalling is still largely unknown. It has been hypothesised that signal transmission via neuropeptides played a crucial role in the regulation of nervous systems in the bilaterian ancestor. Identification, expression and functional analyses of neuropeptides and their receptors across different ...
Ryo Nakamura +4 more
wiley +1 more source
Syndromic convergence (SyCo) reframes aquaculture disease as the synergistic product of climate‐driven stressors, pathobiome communities, and host immune compromise, not single pathogens. A five‐criterion scoring matrix, composite early warning index, and three‐layer intervention framework together operationalize this shift toward predictive ...
Ilhan Altinok
wiley +1 more source
Localization sequences for logarithmic topological cyclic homology
Abstract We introduce the notion of an Ek$\mathbb {E}_k$‐ring with prelogarithmic structure, define logarithmic topological Hochschild homology and logarithmic topological cyclic homology in this context, and establish localization sequences for these theories. Our approach is based on Thom R$R$‐algebras.
John Rognes +2 more
wiley +1 more source
Effects of TRH and TRH analogues on the central regulation of breathing in the rat
Respiratory activity was studied in rats during light halothane anesthesia. Thyrotropin releasing hormone (TRH) and two TRH analogues: the desamidated form (TRH‐OH) and γ‐butyrolactone‐γ‐carbonyl‐L‐histidyl‐L‐prolraamide citrate (DN 1417) were administered intracerebroventricularly.
D Lundberg, J Jonason
exaly +4 more sources
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Valproate modulates TRH receptor, TRH and TRH-like peptide levels in rat brain
Peptides, 2004We have tested our hypothesis that alterations in the levels of TRH receptors, and the synthesis and release of tripeptide TRH, and other neurotropic TRH-like peptides mediate some of the mood stabilizing effects of valproate (Valp). We have directly compared the effect of 1 week of feeding two major mood stabilizers, Valp and lithium chloride (LiCl ...
Albert Sattin, A Eugene Pekary
exaly +4 more sources

