Results 161 to 170 of about 84,409 (332)

Hepatic GCGR is required for the superior weight loss and metabolic effects of a structurally related analogue of the dual GCGR/GLP‐1R agonist survodutide in mice

Diabetes, Obesity and Metabolism, EarlyView.
Fen Long, Tenagne D. Challa, Vissarion Efthymiou, Manuel Klug, Thomas Klein, Heike Neubauer, Christian Wolfrum, Carla Horvath   +7 more
wiley   +1 more source

The Complex Relation of Branched‐Chain Amino Acids and Inflammation in the Obesity and Diabetes Context

Obesity Reviews, EarlyView.
ABSTRACT In a scenario with increasing cases of obesity and diabetes worldwide, branched‐chain amino acids (BCAA) metabolism has become an important factor in the understanding of these pathologies. More recently, its chronic high plasma levels have been postulated, alongside glucose, inflammatory factors, and other molecules, as an important ...
Bernardo Starling‐Soares, Monique Macedo Coelho, Bruna Guerra Campolina, Camila Kümmel Duarte, Tatiani Uceli Maioli   +4 more
wiley   +1 more source

Safety evaluation of the food enzyme triacylglycerol lipase from the pregastric tissues of calves, kids and lambs. [PDF]

EFSA J
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Van Loveren H, Vernis L, Andryszkiewicz M, Cavanna D, Liu Y.   +15 more
europepmc   +2 more sources

Effect of long-term olive oil dietary intervention on postprandial triacylglycerol and factor VII metabolism [PDF]

, 1998
Helen M. Roche, Antonis Zampelas, Jackie ME Knapper, Diane H. WEBB, Cathriona Brooks, Kim G. Jackson, John W. Wright, B J Gould, Antony Kafatos, Michael J. Gibney, Christine M. Williams   +10 more
openalex   +1 more source

Synthetic Biology and Metabolic Engineering of Microalgae for Sustainable Lipid and Terpenoid Production: An Updated Perspective

Plant Biotechnology Journal, EarlyView.
ABSTRACT Microalgae are increasingly recognised as powerful platforms for the sustainable production of lipids and terpenoids, with expanding applications in the food, fuel and biomanufacturing industries. In this updated review, we consolidate and critically assess the most recent advances in synthetic biology and metabolic engineering of key ...
Ty Shitanaka, Yu Wang, Sally Do, Julia Yuson, Samir Kumar Khanal, Krzysztof Zienkiewicz, Zhi‐Yan Du   +6 more
wiley   +1 more source

Plant Lipid Droplets and Derived Lipidic Nano‐Assemblies: Structure, Biogenesis and Pharmaceutical Applications

Plant Biotechnology Journal, EarlyView.
ABSTRACT Lipid droplets (LDs) serve as the primary storage site for neutral lipids in plant cells, with growing evidence supporting many additional biological roles, such as in lipid homeostasis, signalling, trafficking, inflammatory responses and inter‐organelle communication.
Abdulsamie Hanano, Amal Yousfan, Denis J. Murphy   +2 more
wiley   +1 more source

Reducing the Sinapine Levels of Camelina sativa Seeds Through Targeted Genome Editing of REF1

Plant Biotechnology Journal, EarlyView.
ABSTRACT Sinapine (O‐sinapoyl choline) is the major phenolic metabolite typically found in the oil‐rich seeds of Brassicaceae such as Camelina sativa and Brassica napus. It imparts a bitter taste to the seeds as a defence mechanism against herbivores, but it also renders them less palatable to livestock.
Amélie A. Kelly, Martin Fulda, Merle Aden, Ilka N. Abreu, Kirstin Feussner, Ivo Feussner   +5 more
wiley   +1 more source

A Chemical Probe for Increasing Leaf Tocopherol Levels by Coordinated Modulation of Biosynthesis, Competition and Storage

Plant Biotechnology Journal, EarlyView.
ABSTRACT Plant biofortification with phytonutrients typically relies on metabolic engineering strategies known as ‘push’ (enhancing biosynthetic flux), ‘block’ (inhibiting competing pathways) and ‘pull’ (promoting metabolite storage). Here, we describe a novel synthetic compound, X57, that simultaneously targets biosynthesis, competition and storage to
Pablo Perez‐Colao, Gaetan Glauser, Jacobo Cruces, Jorge Lozano‐Juste, Manuel Rodriguez‐Concepcion   +4 more
wiley   +1 more source

Preferential lipolysis of DGAT1 over DGAT2 generated triacylglycerol in Huh7 hepatocytes [PDF]

, 2021
Rajakumar Selvaraj, Sarah V. Zehnder, Russell Watts, Jihong Lian, Randal C. Nelson, Richard Lehner   +5 more
openalex   +1 more source

An α/β‐Hydrolase GmABHD6 Controls Seed Oil Content and Yield in Soybean

Plant Biotechnology Journal, EarlyView.
ABSTRACT Seed oil content is a key trait in soybean, yet its genetic basis remains largely unresolved. Here, we identify GmABHD6, an α/β‐hydrolase domain‐containing gene, as the causal gene underlying a major quantitative trait locus (QTL) for seed oil content on chromosome 16.
Kaixin Yu, Limin Hu, Bo Sun, Zehao Chen, Xu Li, Shiyu Zhang, Huilin Tian, Wenjing Zhang, Shimin Ren, Xue Han, Chang Xu, Siming Wei, Mingliang Yang, Fanjiang Kong, Qingshan Chen, Zhaoming Qi   +15 more
wiley   +1 more source