Results 221 to 230 of about 77,983 (302)

Functional Role of COP1 Gene in Hepatocellular Carcinoma Lipid Metabolism and Stemness

open access: yesGenes to Cells, Volume 31, Issue 3, May 2026.
COP1 promotes HCC lipid metabolism and stemness via the functional interaction with AKR1D1 and TMEM65 genes, respectively, indicating its potential as a therapeutic target for treating primary HCC and preventing metastasis and/or recurrence. ABSTRACT We have previously defined the constitutive photomorphogenic protein 1 (COP1) gene as a therapeutic ...
Eun‐Hye Jeon   +8 more
wiley   +1 more source

Reproductive Importance of Brown Adipose Tissue in the Neotropical Sperm-Storing Vespertilionid Bat Yellowish Myotis: AI Analysis, Lipid Profile, and Androgenic Function. [PDF]

open access: yesMol Reprod Dev
Farias TO   +9 more
europepmc   +1 more source

Genetic Parameter Estimation for Plasma Biomarkers Associated With Energy Reserves During Critical Physiological Stages in Sheep

open access: yesJournal of Animal Breeding and Genetics, Volume 143, Issue 3, Page 443-456, May 2026.
ABSTRACT The ability of ruminants to mobilise and restore body reserves (BR) over time, referred to as BR dynamics, is currently considered an interesting biological component to be included in breeding programs targeting enhanced BR resilience. However, genetic studies of proxies for BR levels and BRD remain scarce, particularly in small ruminants ...
Agnes Nyamiel   +8 more
wiley   +1 more source

Safety evaluation of the food enzyme triacylglycerol lipase from the genetically modified <i>Komagatella phaffii</i> strain LALL-LI2. [PDF]

open access: yesEFSA J
EFSA Panel on Food Enzymes (FEZ)   +17 more
europepmc   +1 more source

Adipose Triglyceride Lipase and Gpr40 Contribute to the Anti‐Contractile Effect of Perivascular Adipose Tissue

open access: yesMicrocirculation, Volume 33, Issue 4, May 2026.
ABSTRACT Objective Perivascular adipose tissue (PVAT) surrounds most peripheral blood vessels and exerts an anti‐contractile influence through paracrine mediators. Although numerous vasoactive factors have been identified, the mechanisms linking adipocyte metabolism to PVAT‐dependent modulation of vascular tone remain poorly defined. Because adipocytes
Miranda Hyatt   +9 more
wiley   +1 more source

Ustilago maydis Phosphatidic Acid and Phosphatidylserine‐Targeting Secreted Lipase Lip3 Is Involved in Pathogenesis

open access: yesMolecular Plant Pathology, Volume 27, Issue 5, May 2026.
Ustilago maydis secreted lipase, Lip3 targets PA and PS and alkalinises the host apoplast, thus promoting virulence. Loss of Lip3 results in reduced apoplastic pH and decreased pathogenicity. ABSTRACT Lipases constitute important virulence factors. By targeting specific lipids involved in various cellular processes, lipases regulate growth, development,
Anisha Roy   +2 more
wiley   +1 more source

Fascinating single‐cell red algae: models for evolution and adaptation

open access: yesNew Phytologist, Volume 250, Issue 3, Page 1424-1437, May 2026.
Summary The unicellular red algae, Cyanidiophyceae, that diverged early during Archaeplastida (algal and plant) evolution, occupy a variety of extreme habitats that are inhospitable for most other eukaryotes. With the use of modern genomics and genetics methods, Cyanidiophyceae show a remarkable taxonomic diversity, share haplodiplophasic life cycles ...
Frédéric Berger   +13 more
wiley   +1 more source

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