Results 51 to 60 of about 4,605 (177)

A double‐blind, placebo‐controlled trial on the antihypertensive treatment effect of a quadruple single‐pill combination

open access: yesThe Journal of Clinical Hypertension, 2021
In a randomized, double‐blind, placebo‐controlled trial, we investigated antihypertensive treatment effect of a quadruple single‐pill combination of reserpine 0.1 mg, dihydralazine 12.5 mg, hydrochlorothiazide 12.5 mg, and triamterene 12.5 mg, and ...
Lei‐Xiao Hu   +8 more
doaj   +1 more source

Effect of triamterene on nucleic acid synthesis [PDF]

open access: yes, 2016
Triamterene is a diuretic with activity in vitro as a folic acid antagonist inhibiting dihydrofolate reductase. Megaloblastosis ifi patients on triamterene was suspected to be due to inhibition of DNA synthesis secondary to triamterene inhibition of ...
Chang, Jae C, Hall, Thomas C
core   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Ion channels

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S152-S241, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +86 more
wiley   +1 more source

Diuretics and Hypokalemia [PDF]

open access: yesActa Medica Iranica, 1970
We have studied hypokalemic action of different diuretics in a cooperative study on 28 patients and our results are as follows: I. 28 patients (18 male and 10 female) were the subject of our present study. 2. E. C. G.
Ali A. Handjani   +2 more
doaj   +2 more sources

7‐Ketodeoxycholic Acid Promotes Colonic Mucosal Healing by Inducing Calcium Release from Endoplasmic Reticulum via the TGR5‐IP3R Pathway

open access: yesAdvanced Science, Volume 12, Issue 42, November 13, 2025.
7‐KDCA functions by driving intestinal epithelial cell migration through induction of calcium release from the endoplasmic reticulum. The findings emphasize a previously unrecognized property of 7‐KDCA in regulating cell migration, a required process for effective epithelial restitution and repair that is particularly critical for patients with UC to ...
Jing Zhang   +9 more
wiley   +1 more source

Investigation of triamterene as an inhibitor of the TGR5 receptor: identification in cells and animals

open access: yesDrug Design, Development and Therapy, 2017
Yingxiao Li,1,2 Kai Chun Cheng,1 Chiang-Shan Niu,3 Shih-Hsiang Lo,3,4 Juei-Tang Cheng,2,5 Ho-Shan Niu31Department of Psychosomatic Internal Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan; 2Department of ...
Li Y   +5 more
doaj  

A Case of Recurrent Renal Aluminum Hydroxide Stone

open access: yesCase Reports in Urology, 2014
Renal stone disease is characterized by the differences depending on the age, gender, and the geographic location of the patients. Seventy-five percent of the renal stone components is the calcium (Ca).
Basri Cakıroglu   +4 more
doaj   +1 more source

Liddle′s syndrome: A case report

open access: yesSaudi Journal of Kidney Diseases and Transplantation, 2015
Liddle′s syndrome or pseudoaldosteronism is a rare autosomal dominant disease mimicking primary hyperaldosteronism, characterized by early-onset hypertension, hypokalemia and hypoaldosteronism, caused by excessive salt and water reabsorption in the ...
Pranav Patel, Reena Kuriacose
doaj   +1 more source

Effect of diuretics on the plasma lipid profile [PDF]

open access: yes, 2017
Hypertension, dyslipidaemia, glucose intolerance (associated with insulin resistance and compensatory hyperinsulinaemia) and other abnormalities are complementary coronary risk factors which often occur in association.
de Courten, M.   +2 more
core  

Micro-RNA family that modulates fibrosis and uses thereof [PDF]

open access: yes, 2017
The present invention relates to the identification of a microRNA family, designated miR-29a-c, that is a key regulator of fibrosis in cardiac tissue. The inventors show that members of the miR-29 family are down-regulated in the heart tissue in response
Olson, Eric N., van Rooij, Eva
core   +1 more source

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