Results 121 to 130 of about 70,161 (298)

Synthesis of 1,2,3-triazoles and applications in the synthesis of BODIPY triazoles

, 2020
The 1,2,3-triazole ring is an important heterocycle which has found wide applications due to its interesting properties. Mainly due to the advent of the copper-catalyzed azide-alkyne cycloaddition (CuAAC) reaction, 1,2,3-triazoles are nowadays unavoidable in the chemical literature. In the past decade, the development of transition metal-free synthetic
openaire   +2 more sources

Anomeric Amide Enabled Divergent Synthesis of Unsymmetrical Ureas, Carbamates, Thioesters, and Amides From Aldehydes

Angewandte Chemie International Edition, EarlyView.
An anomeric amide‐enabled divergent aldehyde functionalization sequence provides one‐pot access to unsymmetrical ureas, carbamates, thiocarbamates, thioesters, and amides. Key to this transformation is the formation of N‐Boc‐hydroxamate intermediates, which serve as platforms for orthogonal activation via Lossen‐type rearrangements, single‐electron ...
Jasper L. Tyler, Meiyi Zeng, Julius Wiener, Marie‐Christin Leusmann, Colin Stein, Constantin G. Daniliuc, Frank Glorius   +6 more
wiley   +1 more source

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

Animal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen, Debashri Mondal, Thangapalam Jawahar Abraham   +2 more
wiley   +1 more source

The roles of side chains in Y6‐series non‐fullerene acceptors for high‐performance organic solar cells

Bulletin of the Korean Chemical Society, EarlyView.
The development of organic solar cells (OSCs) has been driven by structural modifications of Y6‐series non‐fullerene acceptors. In particular, side‐chain engineering regulates solubility, molecular packing, and energy levels, enabling efficiencies to increase from 15.7% to over 20%.
Peddaboodi Gopikrishna, Bomi Kim, Jongnam Park, BongSoo Kim   +3 more
wiley   +1 more source

New Zeolitic Imidazolate Framework‐Derived N‐Doped Carbon LiCl Composites for Sorption Thermal Batteries Utilizing Solar Energy

Carbon Energy, EarlyView.
New hierarchical ZIF‐derived nitrogen‐doped carbons (ZDCs) impregnated with LiCl are promising materials for sorption thermal batteries utilizing solar energy. This study examines the structural properties of ZDCs, the effect of LiCl loading, the enhancement of hydrothermal stability by nanoporous carbon, and the water adsorption properties of a series
Jan Marčec, Marija Švegovec, Matjaž Mazaj, Andraž Krajnc, Boštjan Genorio, Daniel Lager, Nataša Zabukovec Logar, Alenka Ristić   +7 more
wiley   +1 more source

Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden

ChemFoodChem, EarlyView.
ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley   +1 more source

Synthesis and Glycosidase Inhibition Studies of Novel Exoglycals Targeting GH3 Family Enzymes: Insights from Comparative Analysis with Macrolide Antibiotics

Chemistry – A European Journal, EarlyView.
A series of structurally diverse exoglycals was synthesized using a modified Julia‐olefination approach from sugar‐derived precursors. These glycosidase transition‐state mimics were further diversified via CuAAC chemistry to yield triazole‐conjugated analogues.
Elisa Ospanow, Oscar L. Alferez, David L. Jakeman   +2 more
wiley   +1 more source

Triazole-Appended Glycohybrid/CuI-Catalyzed C–C Cross-Coupling of Aryl/Heteroaryl Halides with Alkynyl Sugars [PDF]

This report describes a convenient method for the Cu­(I)-catalyzed Sonogashira cross-coupling reaction of aryl/heteroaryl halides and alkynyl sugars in the presence of a 1,2,3-triazole-appended glycohybrid as a biocompatible ligand. The Sonogashira cross-
Abhishek Gupta (402938), Vinod K. Tiwari (1599811), Sumit K. Singh (11230834), Sunil Kumar (102321), Mangal S. Yadav (11230837)   +4 more
core   +1 more source

The Stabilization of High‐Nitrogen Systems: 10 Catenated Nitrogen Chain

Chemistry – A European Journal, EarlyView.
Improving the understanding of high‐nitrogen materials. ABSTRACT High‐nitrogen materials have attracted intense interest in recent decades due to their unique chemical, physical, and biological properties. Stabilizing high‐nitrogen materials is often challenging as they become more unstable with increasing nitrogen catenation and nitrogen mass ...
Nicholas F. Scherschel, Thomas R. Talbot IV, Matthias Zeller, Davin G. Piercey   +3 more
wiley   +1 more source

Synthetic Strategies for Activity‐Based Probes to Decode Ubiquitin‐Like Modifiers

Chemistry – A European Journal, EarlyView.
ABSTRACT Ubiquitin‐like proteins (Ubls) such as SUMO, NEDD8, ISG15, URM1, UFM1, FAT10, ATG8/ATG12, and FUBI are essential regulators of cellular homeostasis, controlling processes from protein stability and trafficking to immune signaling and autophagy.
Saibal Chanda, Alan Pham, SreeNidhi Karnati, Natalia Soto Rodriguez, Alyssa Toner, Wenshe Ray Liu   +5 more
wiley   +1 more source