Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies
Medicinal Research Reviews, EarlyView.ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva +23 more
wiley +1 more source
Simultaneous electrochemical detection of multiple heavy metal cations using multi-walled carbon nanotubes functionalized with a ferrocenyl-based 1,4-disubstituted-1,2,3-triazole complex. [PDF]
RSC AdvAl Khalyfeh K +8 more
europepmc +1 more source
Boronic Acid Inhibitors of β‐Lactamases: A Promising Strategy Against Antimicrobial Resistance
Medicinal Research Reviews, EarlyView.ABSTRACT The rise of antimicrobial resistance (AMR) poses a critical threat to global health, mostly due to the proliferation of β‐lactamases, a class of enzymes responsible for the inactivation of β‐lactam antibiotics. Among the most promising strategies to restore β‐lactam efficacy is the use of β‐lactamase inhibitors (BLIs), with boronic acid ...
Nicolò Santi +4 more
wiley +1 more source
Quantum Chemical Investigation of the Dimroth Rearrangement of 1-(5-Imino-4,5-dihydro-1H-1,2,3-triazol-1-yl)anthracene-9,10-dione. [PDF]
ChemistryOpenMelnyk D +3 more
europepmc +1 more source
Diverse Uses of Lantibiotics: Exploring New Approaches to Combat Antibiotic Resistance
Medicine Advances, EarlyView.This review illustrates lantibiotics as an alternative therapeutic approach to combat antibiotic resistance, highlighting their diverse sources, including plants, insects, animals, and microorganisms. It further emphasizes their broad therapeutic potential, including antibacterial, antifungal, antiparasitic, antiviral, and anticancer activities (GA ...
Gopalarethinam Janani +5 more
wiley +1 more source
Triazole-based hybrid molecules in anticancer drug discovery: structural classes and mechanistic insights, 2014-2025. [PDF]
Beilstein J Org ChemBhandari M, Goyal A, Yadav D.
europepmc +1 more source
Diverse reactivity of maleimides in polymer science and beyond
Polymer International, Volume 74, Issue 4, Page 296-306, April 2025.This mini‐review provides a thorough overview of maleimide chemistry, highlighting its diverse reactivity in polymer and materials science applications. Abstract Maleimides are remarkably versatile functional groups, capable of participating in homo‐ and copolymerizations, Diels–Alder and (photo)cycloadditions, Michael additions, and other reactions ...
Bruce E Kirkpatrick +2 more
wiley +1 more source
Main‐chain polyfullerenes: Taking fullerene to the next dimension
Polymer International, EarlyView.This short review appraises main‐chain polyfullerenes. Their slow development over 30 years has suddenly boomed with a rapid growth due to exciting developments in solar energy. Abstract This mini‐review gives an overview of the development, chemistry, properties and applications of main‐chain polyfullerenes.
Marco Antônio GB Gomes +4 more
wiley +1 more source
1,2,3-Triazole-linked DNA biosensors: molecular design to real-time applications. [PDF]
RSC AdvBhatoe G +4 more
europepmc +1 more source