Advances in Unconventional and Sustainable Synthetic Approaches to Benzopyran Scaffolds
The Chemical Record, EarlyView.This review provides a comprehensive and critical analysis of low‐impact synthetic methodologies reported in the last 8 years (2018–2026) for the construction of benzopyran‐derived scaffolds, such as coumarins, flavones, chromones, chromenes, and chromanes. The benzopyran scaffold is a versatile family of heterocycles found in a wide range of bioactive
Nathalia B. Sá +4 more
wiley +1 more source
Unravelling recent advances in 1,2,4-triazole-based anticancer agents: synthetic strategies, molecular targets, molecular docking studies, and structure-activity relationships. [PDF]
RSC AdvMartis GJ +3 more
europepmc +1 more source
The Chemical Record, EarlyView.Two decades of synthetic strategies for sulfur‐, selenium‐decorated coumarins are critically surveyed through 44 literature reports, with particular emphasis on derivatives functionalized at the C‐3 and C‐4 positions. This review reports the direct construction of the coumarin framework through cyclization processes and late‐stage functionalization of ...
Bruna R. Schneider +6 more
wiley +1 more source
Discovery of Tetra-Substituted Imidazole Inhibitors of Plasmin. [PDF]
ChemistrySelectSilva S +7 more
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Pesticides and Hypospadias in Southern Brazil: An Ecological Study
Environmental Toxicology, EarlyView.ABSTRACT Rio Grande do Sul ranks among the Brazilian states with the highest pesticide consumption and one of the highest prevalences of hypospadias, a congenital anomaly often associated with prenatal exposure to endocrine‐disrupting chemicals. We assessed the relationship between prenatal pesticide exposure and hypospadias risk through an ecological ...
Ricardo Rohweder +4 more
wiley +1 more source
Design and Synthesis of Novel 1,2,3-Triazole Conjugates Featuring Hydroxamic Acid and Sulfonamide Moieties: Exploring Dual Pharmacophores for Enhanced Biological Activity. [PDF]
Chem Biol Drug DesPagar D +4 more
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The Uninodal 3D 1,2,4‐Triazolate Frameworks 3∞[M5Cl3(Tz)7(TzH)2], M = Mn, Fe
Zeitschrift für anorganische und allgemeine Chemie, EarlyView.Isotypic 3D frameworks of remarkable complexity of the constitution 3∞[M5Cl3(Tz)7(TzH)2]2·NEt3(HCl)0.5, M = Mn, Fe, are reported from solvothermal reactions of the metal chlorides with 1H‐1,2,4‐triazole with assisting triethylamine and pyridine. A complex framework structure is observed as product of reactions of either MnCl2 or FeCl2 together with the
Franziska A. Brede +3 more
wiley +1 more source
Triazole-Based Metal-Organic Frameworks for CO<sub>2</sub> Capture. [PDF]
Nanomaterials (Basel)Nabipour H, Rohani S.
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Bruton tyrosine kinase inhibitors and cardiovascular adverse events
British Journal of Pharmacology, EarlyView.Abstract Bruton tyrosine kinase inhibitors (BTKi) have transformed the management of chronic lymphocytic leukaemia and other B‐cell malignancies, yet their therapeutic benefit is tempered by clinically relevant cardiovascular toxicities (predominantly atrial fibrillation, hypertension, bleeding and ventricular arrhythmias).
Massimiliano Camilli +4 more
wiley +1 more source
Employing 4-Amino-3,5-bis(aminomethyl)-1,2,4-triazole for the Development of Thermally Stable Energetic Salts With Reduced Sensitivity. [PDF]
Chem Asian JKhatri M, Bijlwan A, Das P, Kumar D.
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