We report a systematic study of β‐ketonitrile–modified Prodan‐type solvatochromic fluorophores. The β‐ketonitrile substitution induces marked bathochromic shifts in absorption and emission and significantly enhances fluorescence quantum yields in nonpolar solvents.
Hiroaki Asakawa +3 more
wiley +1 more source
Photochemical and Thermal Activation of a Diarylbismuth Azide
We report the synthesis and characterization of a novel diarylbismuth azide and its divergent reactivity upon thermal or photochemical activation. These findings contribute expanding the reactivity landscape of heavy pnictogen compounds and sets the basis for further investigations. ABSTRACT Azides are widely employed in synthesis as convenient nitrene
Giacomo Pugliese +5 more
wiley +1 more source
Long‐Term Use of Rezafungin: A Case Report and Insights Into Real‐World Access
Transplant Infectious Disease, EarlyView.
Jian Mei Li +2 more
wiley +1 more source
Click Bioconjugation of Aza‐BODIPY Fluorophores to LfcinB Peptides for Improved Biocompatibility
Click bioconjugation attaches NIR aza‐BODIPY fluorophores to LfcinB‐derived anticancer peptides via CuAAC and thiol‐maleimide chemistry. Conjugates exhibit improved predicted solubility while retaining strong NIR absorption (703–730 nm). Peptide‐aza‐BODIPY conjugates induce apoptotic morphology in HeLa cancer cells.
A. Verónica Rodríguez‐Mayor +6 more
wiley +1 more source
Exploiting the Property of a New Series of 1,2,3-Triazole Compounds as Inhibitors of In Vivo and In Vitro Toxic Effects Caused by <i>Bothrops jararacussu</i> Snake Venom. [PDF]
Silva ARD +6 more
europepmc +1 more source
A Ruthenium(CAAC‐5) Olefin Metathesis Catalyst for Bioconjugation
The aqueous instability of ruthenium catalysts restricts olefin metathesis in biological media. A Ru(CAAC‐5) complex bearing an aniline handle is reported that remains active under biologically relevant conditions and enables bioconjugation to proteins, peptides, and an artificial metalloenzyme, providing a robust platform for olefin metathesis in ...
Damian Alexander Graf +4 more
wiley +1 more source
Oxidative Susceptibility of Coumarin-1,2,3-Triazole-Isatin Hybrids: Integrating In Silico CYP-Mediated Metabolism Prediction with Electrochemistry-Mass Spectrometry. [PDF]
Dimkovski A +8 more
europepmc +1 more source
Genetic diversity and antifungal susceptibility among ecological niche populations of Aspergillus flavus in Yaoundé, Cameroon. [PDF]
Kuate MPN +7 more
europepmc +1 more source
Oocytes play crucial roles in maintaining ovarian fate in adult gonochoristic fish. Targeted oocyte ablation with aromatase inhibition triggers the activation of surviving germline stem cells and the transdifferentiation of somatic cells from granoulosa/theca to Sertoli/Leydig lineages, inducing a complete and functional female‐to‐male sex reversal ...
Yang Yang +6 more
wiley +1 more source
Design and synthesis of 1,3,4-oxadiazole-tethered <i>N</i>-substituted isatin hybrids as SARS-CoV-2 main protease inhibitors: biological evaluation, kinetic investigation, and <i>in silico</i> studies. [PDF]
Al-Warhi T +10 more
europepmc +1 more source

