Results 221 to 230 of about 80,033 (290)

Combining Triazole Scaffold Repurposing and Generative Transformer Architecture for Structure-Based Inhibitor Design Targeting the LasR Quorum Sensing Receptor of <i>Pseudomonas aeruginosa</i>. [PDF]

Pharmaceuticals (Basel)
Khan A, Zahid MA, Mohammad A, Al-Jabiry A, Al-Zoubi RM, Shkoor M, Al-Jabiry A, Agouni A.   +7 more
europepmc   +1 more source

Oxadiazolone-Triazole Derivatives as a New Scaffold for Modulation of Angiotensin II-Induced Vascular Contraction. [PDF]

ChemMedChem
Ferreira LFL, Vasconcelos DGA, Santos RCA, Ferreira JG, Araújo AV, Anjos JVD.   +5 more
europepmc   +1 more source

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Triazole antifungals: A review

Drugs of Today, 2015
Invasive fungal infections and systemic mycosis, whether from nosocomial infection or immunodeficiency, have been on an upward trend for numerous years. Despite advancements in antifungal medication, treatment in certain patients can still be difficult for reasons such as impaired organ function, limited administration routes or poor safety profiles of
L R, Peyton, S, Gallagher, M, Hashemzadeh   +2 more
openaire   +2 more sources

Mesoionic 1,2,3-Triazoles and 1,2,3-Triazole Carbenes

2014
Routine access to 1,2,3-triazoles through the copper-catalyzed azide-alkyne “click” cycloaddition reaction has promoted the rapid development of 1,2,3-triazolylidenes as ligands for transition metals. The organometallic complexes containing this kind of N-heterocyclic carbene ligands (NHCs) have shown to possess unique structural characteristics ...
Jesus M. Aizpurua, Maialen Sagartzazu-Aizpurua, Zaira Monasterio   +2 more
openaire   +1 more source

On Triazoles. VI. The acylation of 5‐amino‐1,2,4‐triazoles

Journal of Heterocyclic Chemistry, 1987
AbstractThe isomeric and tautomeric structure of I and II type monoacylated 5‐amino‐1,2,4‐triazole derivatives was studied with the help of their ir, uv, pmr and cmr spectra as well as model compounds prepared for this purpose. It was stated that the structure of the I type ring‐acylated derivatives is 2o and those of their II type isomers is 5a.
József Reiter, László Pongó, Péter Dvortsák   +2 more
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Synthesis of Triazole Nucleoside Derivatives

Nucleosides, Nucleotides & Nucleic Acids, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Zicheng, Li, Shuhua, Chen, Ning, Jiang, Gang, Cui   +3 more
openaire   +2 more sources