Results 231 to 240 of about 70,161 (298)

Synthesis of mono- and di-(<i>C</i>-glycopyranosyl-isoxazol(in)yl) derivatives on aromatic scaffolds and their evaluation as anti-adherence agents of <i>Candida albicans</i>. [PDF]

Front Chem
Kaszás T, Szakács B, Blága T, Doherty K, Keenan-Dillon R, Reynolds S, Kavanagh K, Velasco-Torrijos T, Somsák L, Tóth M.   +9 more
europepmc   +1 more source

Click Reactions in Kinetic Target-Guided Synthesis: Progress in the Discovery of Inhibitors for Biological Targets. [PDF]

Methods Protoc
Parvatkar PT, Satam N.
europepmc   +1 more source

Carbon-iodine atropisomerism on triazole and triazolium frameworks: a breathing axle with divergent adaptivity. [PDF]

Chem Sci
Nambu R, Kikuchi J, Matsumoto A, Yoshikai N.   +3 more
europepmc   +1 more source

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Triazole antifungals: A review

Drugs of Today, 2015
Invasive fungal infections and systemic mycosis, whether from nosocomial infection or immunodeficiency, have been on an upward trend for numerous years. Despite advancements in antifungal medication, treatment in certain patients can still be difficult for reasons such as impaired organ function, limited administration routes or poor safety profiles of
L R, Peyton, S, Gallagher, M, Hashemzadeh   +2 more
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Mesoionic 1,2,3-Triazoles and 1,2,3-Triazole Carbenes

2014
Routine access to 1,2,3-triazoles through the copper-catalyzed azide-alkyne “click” cycloaddition reaction has promoted the rapid development of 1,2,3-triazolylidenes as ligands for transition metals. The organometallic complexes containing this kind of N-heterocyclic carbene ligands (NHCs) have shown to possess unique structural characteristics ...
Jesus M. Aizpurua, Maialen Sagartzazu-Aizpurua, Zaira Monasterio   +2 more
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On Triazoles. VI. The acylation of 5‐amino‐1,2,4‐triazoles

Journal of Heterocyclic Chemistry, 1987
AbstractThe isomeric and tautomeric structure of I and II type monoacylated 5‐amino‐1,2,4‐triazole derivatives was studied with the help of their ir, uv, pmr and cmr spectra as well as model compounds prepared for this purpose. It was stated that the structure of the I type ring‐acylated derivatives is 2o and those of their II type isomers is 5a.
József Reiter, László Pongó, Péter Dvortsák   +2 more
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Synthesis of Triazole Nucleoside Derivatives

Nucleosides, Nucleotides & Nucleic Acids, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Zicheng, Li, Shuhua, Chen, Ning, Jiang, Gang, Cui   +3 more
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QSAR Prediction of Aquatic Toxicity of Triazoles and Benzo-Triazoles

2011
Triazoles and benzo-triazoles (TAZ/BTAZ) are potentially hazardous chemicals that adversely affect humans and other non-target species, and are on the list of substances of very high concern (SVHC) in the European regulation of chemicals REACH. TAZ/BTAZ are synthetic molecules used in various industrial processes (to obtain pharmaceuticals and ...
CASSANI, STEFANO, D’Onofrio E., KOVARICH, SIMONA, PAPA, ESTER, ROY, PARTHA PRATIM, GRAMATICA, PAOLA   +5 more
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Microbiological and in silico evaluation of triazole and bi-triazole derivatives

Revista Eletrônica Acervo Saúde
Objective: To determine the antibacterial activity of triazole and bi-triazole compounds against the pathogens Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and methicillin-resistant Staphylococcus aureus (MRSA). Methods: This targeted research was combined with in silico predictions aimed at the rational and safe screening of
Leandro do Nascimento Martinez, Minelly Azevedo da Silva, Aurileya de Jesus Gouveia, Saara Neri Fialho, Gustavo de Amorim Barbosa Cabral, Quelli Larissa Oliveira Santana, Ivanildes dos Santos Bastos, Patricia Puccinelli Orlandi, Sabrina Baptista Ferreira, Carolina Bioni Garcia Teles   +9 more
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