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Alternate Tricarboxylic Acid Cycle
2021TCA cycle is widely present among all heterotrophs growing aerobically. It operates throughout in the presence of oxygen. However, in some facultative microorganisms, it runs partially with activation of some new enzyme activities and also down-regulation of existing enzymes under anaerobic or microaerophilic conditions.
Rani Gupta, Namita Gupta
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1954
Publisher Summary This chapter discusses the tricarboxylic acid cycle in animal tissues microorganisms and plant material. Thetricarboxylicacid cycle was first proposed in 1937 under the name citric acid cycle to describe the intermediary stages of oxidation of carbohydrate in pigeon breast muscle.
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Publisher Summary This chapter discusses the tricarboxylic acid cycle in animal tissues microorganisms and plant material. Thetricarboxylicacid cycle was first proposed in 1937 under the name citric acid cycle to describe the intermediary stages of oxidation of carbohydrate in pigeon breast muscle.
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2011
Named for its metabolism of the conjugate bases (citrate, isocitrate, and cis-aconitate) of three tricarboxylic acids in the early steps of the pathway, the Tricarboxylic Acid Cycle (or TCA cycle) is known simply as the Citric Acid Cycle. The term “cycle” refers to the fact that the initial six-carbon substrate (citrate) is oxidatively decarboxylated ...
Herbert J. Fromm, Mark S. Hargrove
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Named for its metabolism of the conjugate bases (citrate, isocitrate, and cis-aconitate) of three tricarboxylic acids in the early steps of the pathway, the Tricarboxylic Acid Cycle (or TCA cycle) is known simply as the Citric Acid Cycle. The term “cycle” refers to the fact that the initial six-carbon substrate (citrate) is oxidatively decarboxylated ...
Herbert J. Fromm, Mark S. Hargrove
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Tricarboxylic Acid Cycle and Glyoxylate Bypass
EcoSal Plus, 2005The tricarboxylic acid (TCA) cycle plays two essential roles in metabolism. First, under aerobic conditions the cycle is responsible for the total oxidation of acetyl-CoA that is derived mainly from the pyruvate produced by glycolysis. Second, TCA cycle intermediates are required in the biosynthesis of several amino acids. Although the TCA
John E, Cronan, David, Laporte
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The tricarboxylic acid cycle in fish
Archives of Biochemistry and Biophysics, 1962Abstract The enzymes of the tricarboxylic acid (TCA) cycle have been demonstrated in fish tissue homogenates or mitochondrial preparations. Carp liver mitochondria catalyze the oxidation of TCA intermediates and glutamate accompanied by coupled phosphorylation of adenosine diphosphate.
M, GUMBMANN, A L, TAPPEL
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The Tricarboxylic Acid Cycle in Cyanobacteria
Science, 2011Contrary to expectations, many photosynthetic cyanobacteria maintain a metabolic flexibility that works in the dark.
Shuyi, Zhang, Donald A, Bryant
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Tricarboxylic-Acid-Cycle Intermediates and Cycle Endurance Capacity
International Journal of Sport Nutrition and Exercise Metabolism, 2004The purpose of this study was to determine whether ingestion of a multinutrient supplement containing 3 tricarboxylic-acid-cycle intermediates (TCAIs; pyridoxine-alpha-ketoglutarate, malate, and succinate) and other substances potentially supporting the TCA cycle (such as aspartate and glutamate) would improve cyclists’ time to exhaustion during a ...
Amy C, Brown +2 more
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Tricarboxylic acid cycle enzymes following thiamine deficiency
Neurochemistry International, 2004Thiamine (Vitamin B1) deficiency (TD) leads to memory deficits and neurological disease in animals and humans. The thiamine-dependent enzymes of the tricarboxylic acid (TCA) cycle are reduced following TD and in the brains of patients that died from multiple neurodegenerative diseases.
Parvesh, Bubber +2 more
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1998
Like all organic compounds, glucose will burn in air to produce carbon dioxide and heat. This oxidation process has been harnessed by living organisms not to produce heat, but to trap chemical energy in the form of ATP which can be used for a variety of cellular functions.
J. M. Chesworth +2 more
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Like all organic compounds, glucose will burn in air to produce carbon dioxide and heat. This oxidation process has been harnessed by living organisms not to produce heat, but to trap chemical energy in the form of ATP which can be used for a variety of cellular functions.
J. M. Chesworth +2 more
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Organization of Krebs tricarboxylic acid cycle enzymes
Biochemical Medicine, 1985Binding of enzymes of the Krebs TCA cycle to biological membranes was characterized with respect to intracellular location, susceptibility to various chemical and physical treatments, and extractability as a macromolecular component of the mitochondrial inner membrane.
J B, Robinson, P A, Srere
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