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Trichophyton indotineae : Epidemiology, antifungal resistance and antifungal stewardship strategies [PDF]

Journal of the European Academy of Dermatology and Venereology
There is a concerning trend of widespread and severe superficial fungal infections caused by a new pathogen—Trichophyton indotineae—resistant to standard antifungal therapies. T. indotineae is now spreading globally and evolving. There is increasing urgency for healthcare providers and policy makers to initiate surveillance systems and antifungal ...
Vincent Piguet, Ditte Marie Lindhardt Saunte, Hien Chi Nguyen   +2 more
exaly   +3 more sources

Genomic epidemiology and antifungal resistance of emerging Trichophyton indotineae in China [PDF]

Emerging Microbes and Infections
The emergence and spread of antifungal-resistant Trichophyton indotineae pose an increasing public health concern worldwide. Multidrug-resistant T. indotineae infections have been reported in China in the past few years.
Clement Tsui, Xiaofang Li, Guanzhao Liangmyco   +2 more
exaly   +4 more sources

Emergence of terbinafine-resistant Trichophyton indotineae in Ontario, Canada, 2014–2023 [PDF]

Journal of Clinical Microbiology
Trichophyton indotineae is an emerging fungal pathogen capable of causing extensive recalcitrant dermatophytosis exacerbated by frequently retained terbinafine resistance. Cases of dermatophytosis due to T. indotineae have increased dramatically in India
Julianne Kus, Samir Patel
exaly   +4 more sources

Therapeutic Challenges in Case of Trichophyton indotineae Dermatophytosis, Singapore, 2025 [PDF]

Emerging Infectious Diseases
Trichophyton indotineae is an emerging dermatophyte frequently associated with terbinafine resistance. We report a case of recalcitrant T. indotineae infection in Singapore with limited response despite prolonged azole therapy, which only resolved after
Tiara Joy Foo, Matthew Chung Yi Koh, Ka Lip Chew, Lester Juay, Sean Jiawei Wu   +4 more
doaj   +2 more sources

The Global Antifungal Susceptibility Epidemiology of Trichophyton indotineae Indicating Voriconazole as an Alternative Therapy for Recalcitrant Dermatophytosis. [PDF]

Mycoses
ABSTRACT Background The emergence of Trichophyton indotineae as a multidrug‐resistant dermatophyte has challenged conventional therapeutic approaches for dermatophytosis, leading to a significant therapeutic dilemma. The absence of formal epidemiological cutoff values (ECVs) under the Clinical and Laboratory Standards Institute (CLSI) framework has led
Song G, Xie W, She X, Liu W, Li X, Liang G.   +5 more
europepmc   +2 more sources

A Chinese warning: Terbinafine-resistant Trichophyton indotineae, a global dermatological challenge. [PDF]

J Eur Acad Dermatol Venereol
Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 2, Page 148-149, February 2026.
Zhou X, de Hoog S.
europepmc   +2 more sources

The Evolving Landscape of Dermatophytosis in the UAE: Trichophyton indotineae and Related Genotypes. [PDF]

Mycoses
ABSTRACT Background Dermatophytosis remains one of the most prevalent superficial fungal infections worldwide, increasingly complicated by the emergence of terbinafine‐resistant Trichophyton indotineae. Despite its global spread, molecular and clinical data from the United Arab Emirates (UAE) remain limited.
Vanam HP, Ghazawi A, Aljneibi D, Khan M, Jabeen F, Alsuwaidi AR, Thomsen J, AlBataineh M, Weber S, Gibas C, Wiederhold NP, Al Dhaheri F.   +11 more
europepmc   +2 more sources

Trichophyton indotineae Infection, São Paulo, Brazil, 2024 [PDF]

Emerging Infectious Diseases
We report an extensive, terbinafine-resistant (squalene epoxidase F397L mutation) Trichophyton indotineae infection in a previously healthy businessman from São Paulo, Brazil.
João Nobrega de Almeida, Amanda R. dos Santos, Mario Roberto de S. Trindade, Jeremy A. W. Gold, Fernanda P.M. Razo, Sarah S. Gonçalves, Erick G. Dorlass, Renato de Mello Ruiz, Jacyr Pasternak, Cristovão L.P. Mangueira, Silke Uhrlaß, Pietro Nenoff, Shyam B. Verma, André M. Doi, Marines D.V. Martino   +14 more
doaj   +2 more sources

Spread of Antifungal-Resistant Trichophyton indotineae, United Kingdom, 2017–2024 [PDF]

Emerging Infectious Diseases
We describe 157 cases of Trichophyton indotineae infection in the United Kingdom, mostly in patients linked to southern Asia. T. indotineae is spreading in the United Kingdom and accounts for 38% of dermatophyte isolates referred to the UK National ...
Alireza Abdolrasouli, Richard C. Barton, Andrew M. Borman   +2 more
doaj   +2 more sources

Autochthonous transmission of Trichophyton indotineae through sexual contact, France, 2024 [PDF]

Eurosurveillance
Trichophyton indotineae is an emerging difficult to diagnose dermatophyte species associated with terbinafine resistance, which was initially described in South-Asian and Middle-Eastern countries.
Gentiane Monsel
doaj   +2 more sources