Results 31 to 40 of about 1,558 (165)

Transepithelial Cytophagy by Trichoplax adhaerens F. E. Schulze (Placozoa) Feeding on Yeast

Zeitschrift Fur Naturforschung - Section C Journal of Biosciences, 1986
After accidental observations of unicellular algae trapped in the intermediate layer of Trichoplax, dead yeast cells were offered systematically as a food. Some of them could be found several hours later engulfed by the big tetraploid fibre cells closely beneath the dorsal epithelium of the animal.
exaly   +2 more sources

Identificación y revisión bibliográfica del antecesor de Eumetazoa: "Trichoplax adhaerens" [PDF]

, 2020
The phylum placozoa is a group of primitive animals with great evolutionary and pharmacological interest. It is represented by a few genus, when Trichoplax and its representative species T. adhaerens are most studied. In this work, the knowledge of this species has been bibliographically reviewed, both from an evolutionary point of view and relative to
Camacho Espino, Daniel Matías
openaire   +2 more sources

The early ANTP gene repertoire: insights from the placozoan genome. [PDF]

PLoS ONE, 2008
The evolution of ANTP genes in the Metazoa has been the subject of conflicting hypotheses derived from full or partial gene sequences and genomic organization in higher animals.
Bernd Schierwater, Kai Kamm, Mansi Srivastava, Daniel Rokhsar, Rafael D Rosengarten, Stephen L Dellaporta   +5 more
doaj   +1 more source

Function and phylogeny support the independent evolution of an ASIC-like Deg/ENaC channel in the Placozoa

Communications Biology, 2023
ASIC channels are bilaterian proton-gated sodium channels belonging to the large and functionally-diverse Deg/ENaC family that also includes peptide- and mechanically-gated channels.
Wassim Elkhatib, Luis A. Yanez-Guerra, Tatiana D. Mayorova, Mark A. Currie, Anhadvir Singh, Maria Perera, Julia Gauberg, Adriano Senatore   +7 more
doaj   +1 more source

Why Homoscleromorph Sponges Have Ciliated Epithelia: Evidence for an Ancestral Role in Mucociliary Driven Particle Flux. [PDF]

J Exp Zool B Mol Dev Evol
Epithelia are typically ciliated, except in sponges. Of all Porifera only Homoscleromorphs have motile cilia on their epithelia. Our data highlight the presence of cilia and mucociliary particle transport as a common feature of metazoa and a secondary loss in other sponge lineages.
Price VL, Nanayakkara A, Pasini A, Bazellières E, Vernale A, Rocher C, Borchiellini C, Le Bivic A, Renard E, Leys SP.   +9 more
europepmc   +2 more sources

Born to sense: biophysical analyses of the oxygen sensing prolyl hydroxylase from the simplest animal <i>Trichoplax adhaerens</i>. [PDF]

Hypoxia (Auckl), 2018
Background: In humans and other animals, the chronic hypoxic response is mediated by hypoxia inducible transcription factors (HIFs) which regulate the expression of genes that counteract the effects of limiting oxygen.
Lippl K, Boleininger A, McDonough MA, Abboud MI, Tarhonskaya H, Chowdhury R, Loenarz C, Schofield CJ.   +7 more
europepmc   +3 more sources

Amino acids integrate behaviors in nerveless placozoans

Frontiers in Neuroscience, 2023
Placozoans are the simplest known free-living animals without recognized neurons and muscles but a complex behavioral repertoire. However, mechanisms and cellular bases of behavioral coordination are unknown.
Mikhail A. Nikitin, Daria Y. Romanova, Simkha I. Borman, Leonid L. Moroz, Leonid L. Moroz   +4 more
doaj   +1 more source

Comparative genomics and the nature of placozoan species. [PDF]

PLoS Biology, 2018
Placozoans are a phylum of nonbilaterian marine animals currently represented by a single described species, Trichoplax adhaerens, Schulze 1883. Placozoans arguably show the simplest animal morphology, which is identical among isolates collected ...
Michael Eitel, Warren R Francis, Frédérique Varoqueaux, Jean Daraspe, Hans-Jürgen Osigus, Stefan Krebs, Sergio Vargas, Helmut Blum, Gray A Williams, Bernd Schierwater, Gert Wörheide   +10 more
doaj   +1 more source

Structural basis for binding of the renal carcinoma target hypoxia‐inducible factor 2α to prolyl hydroxylase domain 2

Proteins: Structure, Function, and Bioinformatics, Volume 91, Issue 11, Page 1510-1524, November 2023., 2023
Abstract The hypoxia‐inducible factor (HIF) prolyl‐hydroxylases (human PHD1‐3) catalyze prolyl hydroxylation in oxygen‐dependent degradation (ODD) domains of HIFα isoforms, modifications that signal for HIFα proteasomal degradation in an oxygen‐dependent manner. PHD inhibitors are used for treatment of anemia in kidney disease. Increased erythropoietin
William D. Figg Jr., Giorgia Fiorini, Rasheduzzaman Chowdhury, Yu Nakashima, Anthony Tumber, Michael A. McDonough, Christopher J. Schofield   +6 more
wiley   +1 more source

Defining bone fide effectors of RAS GTPases

BioEssays, Volume 45, Issue 9, September 2023., 2023
RAS GTPases transmit extracellular signals to multiple intracellular signalling pathways through direct interaction with effector proteins. These proteins typically employ RAS‐binding RBD domains to complex with activated GTPases, but the specificity of these interactions remains poorly explored and there remain few data describing the mechanistic ...
Matthew J. Smith
wiley   +1 more source