Results 21 to 30 of about 2,216 (134)
Non-coding RNA annotation of the genome of Trichoplax adhaerens. [PDF]
Nucleic Acids Res, 2009 16021615A detailed annotation of non-protein coding RNAs is typically missing in initial releases of newly sequenced genomes. Here we report on a comprehensive ncRNA annotation of the genome of Trichoplax adhaerens, the presumably most basal metazoan ...
Hertel J +7 more
europepmc +2 more sources
The early ANTP gene repertoire: insights from the placozoan genome. [PDF]
PLoS ONE, 2008 The evolution of ANTP genes in the Metazoa has been the subject of conflicting hypotheses derived from full or partial gene sequences and genomic organization in higher animals.
Bernd Schierwater +5 more
doaj +1 more source
Communications Biology, 2023 ASIC channels are bilaterian proton-gated sodium channels belonging to the large and functionally-diverse Deg/ENaC family that also includes peptide- and mechanically-gated channels.
Wassim Elkhatib +7 more
doaj +1 more source
Amino acids integrate behaviors in nerveless placozoans
Frontiers in Neuroscience, 2023 Placozoans are the simplest known free-living animals without recognized neurons and muscles but a complex behavioral repertoire. However, mechanisms and cellular bases of behavioral coordination are unknown.
Mikhail A. Nikitin +4 more
doaj +1 more source
Comparative genomics and the nature of placozoan species. [PDF]
PLoS Biology, 2018 Placozoans are a phylum of nonbilaterian marine animals currently represented by a single described species, Trichoplax adhaerens, Schulze 1883. Placozoans arguably show the simplest animal morphology, which is identical among isolates collected ...
Michael Eitel +10 more
doaj +1 more source
Neuropeptidergic integration of behavior in Trichoplax adhaerens, an animal without synapses.
J Exp Biol, 2017 Trichoplax adhaerens is a flat, millimeter-sized marine animal that adheres to surfaces and grazes on algae. Trichoplax displays a repertoire of different feeding behaviors despite the apparent absence of a true nervous system with electrical or chemical
Senatore A, Reese TS, Smith CL.
europepmc +2 more sources
Proteins: Structure, Function, and Bioinformatics, Volume 91, Issue 11, Page 1510-1524, November 2023., 2023 Abstract The hypoxia‐inducible factor (HIF) prolyl‐hydroxylases (human PHD1‐3) catalyze prolyl hydroxylation in oxygen‐dependent degradation (ODD) domains of HIFα isoforms, modifications that signal for HIFα proteasomal degradation in an oxygen‐dependent manner. PHD inhibitors are used for treatment of anemia in kidney disease. Increased erythropoietin
William D. Figg Jr. +6 more
wiley +1 more source
Defining bone fide effectors of RAS GTPases
BioEssays, Volume 45, Issue 9, September 2023., 2023 RAS GTPases transmit extracellular signals to multiple intracellular signalling pathways through direct interaction with effector proteins. These proteins typically employ RAS‐binding RBD domains to complex with activated GTPases, but the specificity of these interactions remains poorly explored and there remain few data describing the mechanistic ...
Matthew J. Smith
wiley +1 more source
Protein Science, Volume 32, Issue 7, July 2023., 2023 Abstract The interaction between the transcription factor p53 and the ubiquitin ligase MDM2 results in the degradation of p53 and is well‐studied in cancer biology and drug development. Available sequence data suggest that both p53 and MDM2‐family proteins are present across the animal kingdom.
Filip Mihalič +5 more
wiley +1 more source
The Journal of Physiology, Volume 601, Issue 9, Page 1625-1653, 1 May 2023., 2023 Abstract figure legend Polar view of a phylogram of representative members of the DEG/ENaC superfamily, coloured according to phylum (Annelida, yellow; Arthropoda, light green; Chordata, dark green; Cnidaria, blue; Mollusca, dark purple; Nematoda, magenta; Placozoa, red). Construction of the phylogram is described in Fig. 1.
Eva Kaulich +3 more
wiley +1 more source