Results 21 to 30 of about 2,460 (178)
The cobalamin processing enzyme of Trichoplax adhaerens. [PDF]
J Biol ChemCobalamin (Cbl) is an essential cofactor for methionine synthase and methylmalonyl-CoA mutase, but it must first undergo chemical processing for utilization in animals. In humans, this processing comprises β-axial ligand cleavage and Cbl reduction and is performed by the enzyme MMACHC (HsCblC).
Krams C +8 more
europepmc +4 more sources
Neuropeptidergic integration of behavior in Trichoplax adhaerens, an animal without synapses. [PDF]
J Exp Biol, 2017 ABSTRACT Trichoplax adhaerens is a flat, millimeter-sized marine animal that adheres to surfaces and grazes on algae. Trichoplax displays a repertoire of different feeding behaviors despite the apparent absence of a true nervous system with electrical or chemical synapses. It glides along surfaces to find food, propelled by beating cilia
Senatore A, Reese TS, Smith CL.
europepmc +3 more sources
Metabolic and Chaperone Gene Loss Marks the Origin of Animals: Evidence for Hsp104 and Hsp78 Sharing Mitochondrial Clients [PDF]
, 2015 The evolution of animals involved acquisition of an emergent gene repertoire for gastrulation. Whether loss of genes also co-evolved with this developmental reprogramming has not yet been addressed.
Erives, Albert, Fassler, Jan
core +11 more sources
Functional characterization of p53 pathway components in the ancient metazoan Trichoplax adhaerens. [PDF]
Sci Rep, 2016 AbstractThe identification of genes encoding a p53 family member and an Mdm2 ortholog in the ancient placozoan Trichoplax adhaerens advocates for the evolutionary conservation of a pivotal stress-response pathway observed in all higher eukaryotes. Here, we recapitulate several key functionalities ascribed to this known interacting protein pair by ...
Siau JW +7 more
europepmc +5 more sources
Non-coding RNA annotation of the genome of Trichoplax adhaerens. [PDF]
Nucleic Acids Res, 2009 A detailed annotation of non-protein coding RNAs is typically missing in initial releases of newly sequenced genomes. Here we report on a comprehensive ncRNA annotation of the genome of Trichoplax adhaerens, the presumably most basal metazoan whose genome has been published to-date.
Hertel J +7 more
europepmc +6 more sources
Why Homoscleromorph Sponges Have Ciliated Epithelia: Evidence for an Ancestral Role in Mucociliary Driven Particle Flux. [PDF]
J Exp Zool B Mol Dev EvolEpithelia are typically ciliated, except in sponges. Of all Porifera only Homoscleromorphs have motile cilia on their epithelia. Our data highlight the presence of cilia and mucociliary particle transport as a common feature of metazoa and a secondary loss in other sponge lineages.
Price VL +9 more
europepmc +2 more sources
The early ANTP gene repertoire: insights from the placozoan genome. [PDF]
PLoS ONE, 2008 The evolution of ANTP genes in the Metazoa has been the subject of conflicting hypotheses derived from full or partial gene sequences and genomic organization in higher animals.
Bernd Schierwater +5 more
doaj +1 more source
Communications Biology, 2023 ASIC channels are bilaterian proton-gated sodium channels belonging to the large and functionally-diverse Deg/ENaC family that also includes peptide- and mechanically-gated channels.
Wassim Elkhatib +7 more
doaj +1 more source
Amino acids integrate behaviors in nerveless placozoans
Frontiers in Neuroscience, 2023 Placozoans are the simplest known free-living animals without recognized neurons and muscles but a complex behavioral repertoire. However, mechanisms and cellular bases of behavioral coordination are unknown.
Mikhail A. Nikitin +4 more
doaj +1 more source
Comparative genomics and the nature of placozoan species. [PDF]
PLoS Biology, 2018 Placozoans are a phylum of nonbilaterian marine animals currently represented by a single described species, Trichoplax adhaerens, Schulze 1883. Placozoans arguably show the simplest animal morphology, which is identical among isolates collected ...
Michael Eitel +10 more
doaj +1 more source