Evolution of the perlecan/HSPG2 gene and its activation in regenerating Nematostella vectensis. [PDF]
PLoS ONE, 2015 The heparan sulfate proteoglycan 2 (HSPG2)/perlecan gene is ancient and conserved in all triploblastic species. Its presence maintains critical cell boundaries in tissue and its large (up to ~900 kDa) modular structure has prompted speculation about the ...
Curtis R Warren +5 more
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Deep RNA sequencing reveals the smallest known mitochondrial micro exon in animals: The placozoan cox1 single base pair exon. [PDF]
PLoS ONE, 2017 The phylum Placozoa holds a key position for our understanding of the evolution of mitochondrial genomes in Metazoa. Placozoans possess large mitochondrial genomes which harbor several remarkable characteristics such as a fragmented cox1 gene and trans ...
Hans-Jürgen Osigus +2 more
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Frontiers in Endocrinology, 2022 Bilateria have bilateral symmetry and are subdivided into Deuterostomia (animals like vertebrates) and Protostomia (animals like insects and mollusks).
Frank Hauser +3 more
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Biophysical Characterization and Evolutionary Analysis of the Presynaptic Voltage-gated calcium (Cav2) Channel in Trichoplax adhaerens [PDF]
, 2018 Trichoplax adhaerens is a primitive metazoan with six cell types that lacks a nervous system and synapses. One cell type, dubbed gland cells, line the periphery of its flat disc- shaped body and resemble neurons by expressing membrane apposed secretory ...
Abdallah, Salsabil
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Comparative genomics of large mitochondria in placozoans.
PLoS Genetics, 2007 The first sequenced mitochondrial genome of a placozoan, Trichoplax adhaerens, challenged the conventional wisdom that a compact mitochondrial genome is a common feature among all animals.
Ana Y Signorovitch +2 more
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Apoptosis and cell cycle regulation in a basal model system : insights from the placozoan Trichoplax adhaerens [PDF]
, 2020 Complex gene networks regulated by master control genes are critical for the coordination of fundamental molecular and cellular processes in metazoans. Their misfunction might cause severe diseases like cancer.
Rolfes, Sarah
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A novel study of Trichoplax adhaerens tissue strain using hot and kiln formed glass processes
, 2023 Tissue monolayers are among the most ubiquitous and simple forms of tissue architecturefound throughout animal physiology. One-cell-thick monolayers have drastic increases in tensile strength compared to individual cellular components, but they remain ...
Delli-Santi, Jack
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Comparative genomics of neuroglobin reveals its early origins. [PDF]
PLoS ONE, 2012 Neuroglobin (Ngb) is a hexacoordinated globin expressed mainly in the central and peripheral nervous system of vertebrates. Although several hypotheses have been put forward regarding the role of neuroglobin, its definite function remains uncertain.
Jasmin Dröge +3 more
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Concatenated analysis sheds light on early metazoan evolution and fuels a modern "urmetazoon" hypothesis. [PDF]
PLoS Biology, 2009 For more than a century, the origin of metazoan animals has been debated. One aspect of this debate has been centered on what the hypothetical "urmetazoon" bauplan might have been.
Bernd Schierwater +7 more
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Molecular origin of mesoderm : conservation of T-box genes in non-bilaterian animals [PDF]
, 2003 Several members of the T-box gene family were characterized from cnidarians, ctenophores, sponges and placozoans, which are considered as the four metazoan phyla at the basis of animal evolution leading to bilaterians.
Martinelli, Cosimo
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