Non-coding RNA annotation of the genome of Trichoplax adhaerens. [PDF]
Nucleic Acids Res, 2009 A detailed annotation of non-protein coding RNAs is typically missing in initial releases of newly sequenced genomes. Here we report on a comprehensive ncRNA annotation of the genome of Trichoplax adhaerens, the presumably most basal metazoan whose genome has been published to-date.
Hertel J +7 more
europepmc +7 more sources
Trichoplax adhaerens reveals a network of nuclear receptors sensitive to 9-cis-retinoic acid at the base of metazoan evolution [PDF]
PeerJ, 2017 Trichoplax adhaerens, the only known species of Placozoa is likely to be closely related to an early metazoan that preceded branching of Cnidaria and Bilateria.
Jan Philipp Novotný +9 more
doaj +4 more sources
Neuropeptidergic integration of behavior in Trichoplax adhaerens, an animal without synapses. [PDF]
J Exp Biol, 2017 ABSTRACT Trichoplax adhaerens is a flat, millimeter-sized marine animal that adheres to surfaces and grazes on algae. Trichoplax displays a repertoire of different feeding behaviors despite the apparent absence of a true nervous system with electrical or chemical synapses. It glides along surfaces to find food, propelled by beating cilia
Senatore A, Reese TS, Smith CL.
europepmc +4 more sources
Functional characterization of p53 pathway components in the ancient metazoan Trichoplax adhaerens. [PDF]
Sci Rep, 2016 AbstractThe identification of genes encoding a p53 family member and an Mdm2 ortholog in the ancient placozoan Trichoplax adhaerens advocates for the evolutionary conservation of a pivotal stress-response pathway observed in all higher eukaryotes. Here, we recapitulate several key functionalities ascribed to this known interacting protein pair by ...
Siau JW +7 more
europepmc +7 more sources
The ventral epithelium of Trichoplax adhaerens deploys in distinct patterns cells that secrete digestive enzymes, mucus or diverse neuropeptides [PDF]
Biology Open, 2019 The disk-shaped millimeter-sized marine animal, Trichoplax adhaerens, is notable because of its small number of cell types and primitive mode of feeding.
Tatiana D. Mayorova +4 more
doaj +4 more sources
Apicortin, a Putative Apicomplexan-Specific Protein, Is Present in Deep-Branching Opisthokonts [PDF]
BiologyApicortin, a tubulin/microtubule-binding protein, was first described in 2009 as a protein characteristic of apicomplexans; it was found to be present in all Apicomplexa genomes already sequenced.
Ferenc Orosz
doaj +2 more sources
Correction: Upregulation of DNA repair genes and cell extrusion underpin the remarkable radiation resistance of Trichoplax adhaerens. [PDF]
PLoS Biology[This corrects the article DOI: 10.1371/journal.pbio.3001471.].
Angelo Fortunato +3 more
doaj +2 more sources
Long-term dynamics of placozoan culture: emerging models for population and space biology [PDF]
Frontiers in Cell and Developmental BiologyAs the simplest free-living animal, Trichoplax adhaerens (Placozoa) is emerging as a powerful paradigm to decipher molecular and cellular bases of behavior, enabling integrative studies at all levels of biological organization in the context of metazoan ...
Daria Y. Romanova +6 more
doaj +2 more sources
Coordinated cellular behavior regulated by epinephrine neurotransmitters in the nerveless placozoa [PDF]
Nature CommunicationsUnderstanding how cells communicated before the evolution of nervous systems in early metazoans is key to unraveling the origins of multicellular life.
Minjun Jin +7 more
doaj +2 more sources
Multi-domain O-GlcNAcase structures reveal allosteric regulatory mechanisms [PDF]
Nature CommunicationsNucleocytoplasmic protein O-GlcNAcylation is a dynamic modification catalysed by O-GlcNAc transferase (OGT) and reversed by O-GlcNAc hydrolase (OGA), whose activities are regulated through largely unknown O-GlcNAc-dependent feedback mechanisms.
Sara Basse Hansen +10 more
doaj +3 more sources