Results 81 to 90 of about 1,406 (173)

Emergence, development and diversification of the TGF-β signalling pathway within the animal kingdom

open access: yesBMC Evolutionary Biology, 2009
Background The question of how genomic processes, such as gene duplication, give rise to co-ordinated organismal properties, such as emergence of new body plans, organs and lifestyles, is of importance in developmental and evolutionary biology.
Moustakas Aristidis   +5 more
doaj   +1 more source

The backbone of the post-synaptic density originated in a unicellular ancestor of choanoflagellates and metazoans

open access: yesBMC Evolutionary Biology, 2010
Background Comparative genomics of the early diverging metazoan lineages and of their unicellular sister-groups opens new window to reconstructing the genetic changes which preceded or accompanied the evolution of multicellular body plans.
Manuel Michaël, Alié Alexandre
doaj   +1 more source

A clustered set of three Sp-family genes is ancestral in the Metazoa: evidence from sequence analysis, protein domain structure, developmental expression patterns and chromosomal location

open access: yesBMC Evolutionary Biology, 2010
Background The Sp-family of transcription factors are evolutionarily conserved zinc finger proteins present in many animal species. The orthology of the Sp genes in different animals is unclear and their evolutionary history is therefore controversially ...
Wimmer Ernst A   +2 more
doaj   +1 more source

A conserved cluster of three PRD-class homeobox genes (homeobrain, rx and orthopedia) in the Cnidaria and Protostomia

open access: yesEvoDevo, 2010
Background Homeobox genes are a superclass of transcription factors with diverse developmental regulatory functions, which are found in plants, fungi and animals.
Mazza Maureen E   +4 more
doaj   +1 more source

Expression and phylogenetic analysis of the zic gene family in the evolution and development of metazoans

open access: yesEvoDevo, 2010
Background zic genes are members of the gli/glis/nkl/zic super-family of C2H2 zinc finger (ZF) transcription factors. Homologs of the zic family have been implicated in patterning neural and mesodermal tissues in bilaterians.
Layden Michael J   +4 more
doaj   +1 more source

Genomic organization of eukaryotic tRNAs

open access: yesBMC Genomics, 2010
Background Surprisingly little is known about the organization and distribution of tRNA genes and tRNA-related sequences on a genome-wide scale. While tRNA gene complements are usually reported in passing as part of genome annotation efforts, and ...
Prohaska Sonja J   +6 more
doaj   +1 more source

The evolutionary diversification of LSF and Grainyhead transcription factors preceded the radiation of basal animal lineages

open access: yesBMC Evolutionary Biology, 2010
Background The transcription factors of the LSF/Grainyhead (GRH) family are characterized by the possession of a distinctive DNA-binding domain that bears no clear relationship to other known DNA-binding domains, with the possible exception of the p53 ...
Kaufman Les   +5 more
doaj   +1 more source

Conserved biophysical features of the CaV2 presynaptic Ca2+ channel homologue from the early-diverging animal Trichoplax adhaerens. [PDF]

open access: yesJ Biol Chem, 2020
Gauberg J   +6 more
europepmc   +1 more source

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