Results 61 to 70 of about 131 (115)

Long-term dynamics of placozoan culture: emerging models for population and space biology

Frontiers in Cell and Developmental Biology
As the simplest free-living animal, Trichoplax adhaerens (Placozoa) is emerging as a powerful paradigm to decipher molecular and cellular bases of behavior, enabling integrative studies at all levels of biological organization in the context of metazoan ...
Daria Y. Romanova, Alexander A. Povernov, Mikhail A. Nikitin, Simkha I. Borman, Yana A. Frank, Leonid L. Moroz, Leonid L. Moroz   +6 more
doaj   +1 more source

Beauty in the beast – Placozoan biodiversity explored through molluscan predator genomics

Ecology and Evolution, Volume 14, Issue 4, April 2024.
Previous assumptions about the primary habitat of Placozoa are challenged, and their broader diversity beyond disc‐shaped grazers in coastal waters is revealed. The discovery of placozoan‐predatory sea slugs prompts consideration of a new ecological niche: seafloor sediment interstices.
Michael Eitel, Hans‐Jürgen Osigus, Bastian Brenzinger, Gert Wörheide   +3 more
wiley   +1 more source

Proteoglycans in mechanobiology of tissues and organs: Normal functions and mechanopathology

Proteoglycan Research, Volume 2, Issue 2, April-June 2024.
Abstract Proteoglycans (PGs) are a diverse class of glycoconjugates that serve critical functions in normal mechanobiology and mechanopathology. Both the protein cores and attached glycosaminoglycan (GAG) chains function in mechanically sensitive processes, and loss of either can contribute to development of pathological conditions. PGs function as key
Mary C. Farach‐Carson, Danielle Wu, Cristiane Miranda França   +2 more
wiley   +1 more source

Importance of fatty acid binding proteins in cellular function and organismal metabolism

Journal of Cellular and Molecular Medicine, Volume 28, Issue 5, March 2024.
Abstract Fatty acid binding proteins (Fabps) are small soluble proteins that are abundant in the cytosol. These proteins are known to bind a myriad of small hydrophobic molecules and have been postulated to serve a variety of roles, yet their precise functions have remained an enigma over half a century of study.
Luis B. Agellon
wiley   +1 more source

Coordinated cellular behavior regulated by epinephrine neurotransmitters in the nerveless placozoa

Nature Communications
Understanding how cells communicated before the evolution of nervous systems in early metazoans is key to unraveling the origins of multicellular life.
Minjun Jin, Wanqing Li, Zhongyu Ji, Guotao Di, Meng Yuan, Yifan Zhang, Yunsi Kang, Chengtian Zhao   +7 more
doaj   +1 more source

Evolution of selenoproteins in the metazoan

BMC Genomics, 2012
Background The selenocysteine (Sec) containing proteins, selenoproteins, are an important group of proteins present throughout all 3 kingdoms of life.
Jiang Liang, Ni Jiazuan, Liu Qiong
doaj   +1 more source

Emergence, development and diversification of the TGF-β signalling pathway within the animal kingdom

BMC Evolutionary Biology, 2009
Background The question of how genomic processes, such as gene duplication, give rise to co-ordinated organismal properties, such as emergence of new body plans, organs and lifestyles, is of importance in developmental and evolutionary biology.
Moustakas Aristidis, Freilich Shiri, Goldovsky Leon, Huminiecki Lukasz, Ouzounis Christos, Heldin Carl-Henrik   +5 more
doaj   +1 more source

The backbone of the post-synaptic density originated in a unicellular ancestor of choanoflagellates and metazoans

BMC Evolutionary Biology, 2010
Background Comparative genomics of the early diverging metazoan lineages and of their unicellular sister-groups opens new window to reconstructing the genetic changes which preceded or accompanied the evolution of multicellular body plans.
Manuel Michaël, Alié Alexandre
doaj   +1 more source

A clustered set of three Sp-family genes is ancestral in the Metazoa: evidence from sequence analysis, protein domain structure, developmental expression patterns and chromosomal location

BMC Evolutionary Biology, 2010
Background The Sp-family of transcription factors are evolutionarily conserved zinc finger proteins present in many animal species. The orthology of the Sp genes in different animals is unclear and their evolutionary history is therefore controversially ...
Wimmer Ernst A, Prpic Nikola-Michael, Schaeper Nina D   +2 more
doaj   +1 more source

Multi-domain O-GlcNAcase structures reveal allosteric regulatory mechanisms

Nature Communications
Nucleocytoplasmic protein O-GlcNAcylation is a dynamic modification catalysed by O-GlcNAc transferase (OGT) and reversed by O-GlcNAc hydrolase (OGA), whose activities are regulated through largely unknown O-GlcNAc-dependent feedback mechanisms.
Sara Basse Hansen, Sergio G. Bartual, Huijie Yuan, Olawale G. Raimi, Andrii Gorelik, Andrew T. Ferenbach, Kristian Lytje, Jan Skov Pedersen, Taner Drace, Thomas Boesen, Daan M. F. van Aalten   +10 more
doaj   +1 more source