Results 181 to 190 of about 9,044 (210)
Some of the next articles are maybe not open access.
ROS: Trichothecenes’ handy weapon?
Food and Chemical Toxicology, 2020Trichothecenes are a class of toxic secondary metabolites produced by filamentous fungi such as Fusarium, which pose a threat to human and animal health. Among them, T-2 toxin and deoxynivalenol (DON) have attracted the most attention because of their extensive pollution and strong toxicity.
Zhiwen Xu +5 more
openaire +3 more sources
Haematotoxicity of trichothecenes
Toxicology Letters, 2004Human toxicosis induced by consumption of foodstuffs contaminated with trichothecenes presents one common major symptom: a haematological perturbation manifesting principally as thrombocytopenia and leukopenia. The patients have rapidly progressing coagulation problems, and compromised resistance to infections.
openaire +3 more sources
Chemical Synthesis of the Trichothecenes
1985That research in the trichothecene field is an area of intense interest cannot be disputed. In the years 1982 and 1983, there were more than 500 publications dealing with this subject, including more than 30 reviews. In addition, a comprehensive monograph has recently appeared (151).
N. R. Schmuff, P. G. McDougal
openaire +3 more sources
Metabolism of Trichothecene Mycotoxins
The Journal of Biochemistry, 1978The substrate specificity of microsomal nonspecific carboxyesterase [EC 3.1.1.1] from rabbit and rat livers was studied in vitro by using seven (A)-type and six (B)-type 12,13-epoxytrichothecene mycotoxins. The C-4 acetyl residues of diacetoxyscirpenol, T-2 toxin, monoacetylnivalenol (fusarenon-X), and diacetylnivalenol were selectively hydrolyzed by ...
Kenji Ishii +3 more
openaire +3 more sources
A yeast bioassay for trichothecenes
Natural Toxins, 1999Like all eucaryotic cells, yeasts are sensitive to trichothecenes, especially T-2 toxin and verrucarin A. Based on this sensitivity, a yeast bioassay was developed to evaluate the toxicity of corn samples. The bioassay was optimized using spiked maize extracts. The toxicity of samples was defined as toxicity equivalent to a certain concentration of T-2
openaire +3 more sources
Analysis of Trichothecene Mycotoxins
Applied Spectroscopy, 1983Diagnostic toxicology requires the analysis of feeds and diagnostic specimens for the toxic principles involved in the poisoning. The trichothecene mycotoxins are both acutely irritating and very poisonous. They may be analyzed by gas chromatography (GC) and thin layer chromatography (TLC) and their presence confirmed by gas chromatography/mass ...
R. Pfeiffer +3 more
openaire +2 more sources
Influence of processing on trichothecene levels
Toxicology Letters, 2004Trichothecene mycotoxins frequently occur in cereal grains that are intended for food production. The process of converting grains into food and drinks for consumers has significant effects on the levels of toxins in the final food. Surveillance of retail food and drinks of cereal origin demonstrates that trichothecenes do survive the production ...
S. Patel, Clare M. Hazel
openaire +3 more sources
Trichothecenes and their analysis
Journal of the American Oil Chemists' Society, 1979AbstractThe analysis of foods and feeds for the naturally occurringFusarium produced trichothecenes is reviewed. Each major step (extraction, purification and detection‐quantitation) is discussed. Although none of the extraction solvents has been thoroughly evaluated, aqueous metanol is the preferred system in most of the published procedures.
openaire +2 more sources
Trichodiene is a precursor to trichothecenes
Journal of the Chemical Society, Chemical Communications, 1989Trichodiene was rigorously proven to be a biosynthetic precursor to the major trichothecenes in Fusarium culmorum: 3-acetyldeoxynivalenol and sambucinol; bazzanene, an unnatural diastereoisomer of trichodiene (with a β-methyl at C-15), was not incorporated into trichothecenes.
Lolita O. Zamir +4 more
openaire +2 more sources