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Prevention strategies for trichothecenes
Toxicology Letters, 2004Contamination of cereal commodities with mycotoxins represents a significant hazard to consumer health and has thus received increasing attention from food safety authorities and legislators. For trichothecenes, and deoxynivalenol (DON) in particular, the imminent implementation of legislative limits has focused attention on ways to prevent entry of ...
David, Aldred, Naresh, Magan
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Biosynthesis of Trichothecenes and Apotrichothecenes
Journal of Agricultural and Food Chemistry, 1999Fusarium culmorum produces two major trichothecenes, 3-acetyldeoxynivalenol and sambucinol, and some minor apotrichothecenes. It was desired to investigate if during their biosynthesis a C-11-keto intermediate was involved. To verify this postulate, trichodiene, a known precursor to trichothecenes, was synthesized with two deuteriums at C-11 and one at
L O, Zamir +3 more
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Determination of trichothecenes in cereals
Journal of Chromatography A, 1999An effective method for the determination of seven trichothecenes-deoxynivalenol (DON), nivalenol (NIV), T-2 tetraol (T-24), fusarenon-X (FUS-X), diacetoxyscirpenol (DAS), T-2 toxin (T-2), HT-2 toxin (HT-2) in cereals is presented. Gel permeation chromatography on Bio-Beads S-X3 was used for clean-up of acetonitrile-methanol extract.
F, Kotal +4 more
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Trichothecenes: Structure-Toxic Activity Relationships
Current Drug Metabolism, 2013Trichothecenes comprise a large family of structurally related toxins mainly produced by fungi belonging to the genus Fusarium. Among trichothecenes, type A and type B are of the most concern due to their broad and highly toxic nature. In order to address structure-activity relationships (SAR) of trichothecenes, relationships between structural ...
Qinghua, Wu +3 more
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Chemical Synthesis of the Trichothecenes
1985That research in the trichothecene field is an area of intense interest cannot be disputed. In the years 1982 and 1983, there were more than 500 publications dealing with this subject, including more than 30 reviews. In addition, a comprehensive monograph has recently appeared (151).
P G, McDougal, N R, Schmuff
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Analysis of Trichothecene Mycotoxins
Applied Spectroscopy, 1983Diagnostic toxicology requires the analysis of feeds and diagnostic specimens for the toxic principles involved in the poisoning. The trichothecene mycotoxins are both acutely irritating and very poisonous. They may be analyzed by gas chromatography (GC) and thin layer chromatography (TLC) and their presence confirmed by gas chromatography/mass ...
H. M. Stahr +3 more
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The Trichothecenes and Their Biosynthesis
ChemInform, 2007AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
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A yeast bioassay for trichothecenes
Natural Toxins, 1999Like all eucaryotic cells, yeasts are sensitive to trichothecenes, especially T-2 toxin and verrucarin A. Based on this sensitivity, a yeast bioassay was developed to evaluate the toxicity of corn samples. The bioassay was optimized using spiked maize extracts. The toxicity of samples was defined as toxicity equivalent to a certain concentration of T-2
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ChemInform Abstract: Macrocyclic Trichothecenes
ChemInform, 1994AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
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