Role of the Gene tri14 in Biosynthesis of the Trichothecene Toxin Harzianum A in Trichoderma arundinaceum [PDF]
ToxinsTrichothecenes are a family of toxic metabolites produced by multiple fungal species. All trichothecene analogs include an epoxide-containing tricyclic structure known as 12,13-epoxytrichothec-9-ene (EPT) but differ by the presence, absence and types of ...
Natalia Martínez-Reyes +6 more
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Effect of Photoperiod on Growth and Production of Trichothecene Mycotoxins in Fusarium graminearum [PDF]
ToxinsFusarium graminearum is a plant-pathogenic and mycotoxin-producing fungus of major concern to cereal production worldwide. There are genetically distinct populations of the pathogen that are associated with different trichothecene mycotoxin profiles.
William T. Hay +9 more
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AN IN VITRO ESTIMATION OF CYTOTOXICITY OF FUSARIUM TRICHOTHECENE ON THE BREAST CANCER CELL LINE [PDF]
Сибирский онкологический журнал, 2020 trichothecenes and their derivatives have recently attracted much attention of researchers with respect of their potential role in medicine, including for the treatment of different types of cancer.
Rin. S. Mukhammadiev +6 more
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Molecules, 2016 Trichothecene mycotoxins are a type of sesquiterpenoid produced by various kinds of plantpathogenic fungi. In this study, two trichothecene toxins, namely, a novel cytotoxic epiroridin acid and a known trichothecene, mytoxin B, were isolated from the ...
Wei Ye +7 more
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Microorganisms, 2022 The Fusarium graminearum species complex is the main causal agent of wheat head blight worldwide. Trichothecenes produced by the pathogen in infected grains have important food safety implications.
Jianhua Wang +7 more
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Regulatory mechanism of trichothecene biosynthesis in Fusarium graminearum [PDF]
Frontiers in Microbiology, 2023 Among the genes involved in the biosynthesis of trichothecene (Tri genes), Tri6 and Tri10 encode a transcription factor with unique Cys2His2 zinc finger domains and a regulatory protein with no consensus DNA-binding sequences, respectively.
Maydelene Xiao Xuan Liew +4 more
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Toxins, 2013 The correlation of ATP citrate lyase (ACL) and acetyl CoA levels with trichothecene production in Fusarium graminearum was investigated using an inhibitor (precocene II) and an enhancer (cobalt chloride) of trichothecene production by changing carbon ...
Naoko Sakamoto +6 more
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Cytotoxic trichothecene derivatives from Trichothecium sp. DWS815 [PDF]
Natural Products and BioprospectingTen novel trichothecene sesquiterpenoids including two new seco-trichothecenes, trichotheciumones A (1) and B (2), a new trichothecene sesquiterpenoid glycoside, trichothecinoside A (3), and seven new trichothecene sesquiterpenoids, trichothecrotocins T ...
Peng-Ju Xu +10 more
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Cellular development associated with induced mycotoxin synthesis in the filamentous fungus Fusarium graminearum. [PDF]
PLoS ONE, 2013 Several species of the filamentous fungus Fusarium colonize plants and produce toxic small molecules that contaminate agricultural products, rendering them unsuitable for consumption. Among the most destructive of these species is F.
Jon Menke +3 more
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Precocene II, a Trichothecene Production Inhibitor, Binds to Voltage-Dependent Anion Channel and Increases the Superoxide Level in Mitochondria of Fusarium graminearum. [PDF]
PLoS ONE, 2015 Precocene II, a constituent of essential oils, shows antijuvenile hormone activity in insects and inhibits trichothecene production in fungi. We investigated the molecular mechanism by which precocene II inhibits trichothecene production in Fusarium ...
Tomohiro Furukawa +5 more
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