Results 11 to 20 of about 8,048 (181)

AN IN VITRO ESTIMATION OF CYTOTOXICITY OF FUSARIUM TRICHOTHECENE ON THE BREAST CANCER CELL LINE

Сибирский онкологический журнал, 2020
trichothecenes and their derivatives have recently attracted much attention of researchers with respect of their potential role in medicine, including for the treatment of different types of cancer.
Rin. S. Mukhammadiev, Rish. S. Mukhammadiev, V. V. Biryulya, I. I. Idiyatov, A. A. Nabatov, A. P. Glinushkin, L. R. Valiullin   +6 more
doaj   +1 more source

Correlation of ATP Citrate Lyase and Acetyl CoA Levels with Trichothecene Production in Fusarium graminearum

Toxins, 2013
The correlation of ATP citrate lyase (ACL) and acetyl CoA levels with trichothecene production in Fusarium graminearum was investigated using an inhibitor (precocene II) and an enhancer (cobalt chloride) of trichothecene production by changing carbon ...
Naoko Sakamoto, Rie Tsuyuki, Tomoya Yoshinari, Jermnak Usuma, Tomohiro Furukawa, Hiromichi Nagasawa, Shohei Sakuda   +6 more
doaj   +1 more source

Two Trichothecene Mycotoxins from Myrothecium roridum Induce Apoptosis of HepG-2 Cells via Caspase Activation and Disruption of Mitochondrial Membrane Potential

Molecules, 2016
Trichothecene mycotoxins are a type of sesquiterpenoid produced by various kinds of plantpathogenic fungi. In this study, two trichothecene toxins, namely, a novel cytotoxic epiroridin acid and a known trichothecene, mytoxin B, were isolated from the ...
Wei Ye, Yuchan Chen, Haohua Li, Weimin Zhang, Hongxin Liu, Zhanghua Sun, Taomei Liu, Saini Li   +7 more
doaj   +1 more source

Deoxynivalenol (Vomitoxin)-Induced Anorexia Is Induced by the Release of Intestinal Hormones in Mice

Toxins, 2021
Deoxynivalenol (DON), also known as vomitoxin, is a mycotoxin that can cause antifeeding and vomiting in animals. However, the mechanism of DON inducing anorexia is complicated.
Jianming Yue, Dawei Guo, Xiuge Gao, Jiacai Wang, Eugenie Nepovimova, Wenda Wu, Kamil Kuca   +6 more
doaj   +1 more source

Chlorogenic Acid and Maize Ear Rot Resistance: A Dynamic Study Investigating Fusarium graminearum Development, Deoxynivalenol Production, and Phenolic Acid Accumulation

Molecular Plant-Microbe Interactions, 2012
Fusarium graminearum is the causal agent of Gibberella ear rot and produces trichothecene mycotoxins. Basic questions remain unanswered regarding the kernel stages associated with trichothecene biosynthesis and the kernel metabolites potentially involved
Vessela Atanasova-Penichon, Sebastien Pons, Laetitia Pinson-Gadais, Adeline Picot, Gisèle Marchegay, Marie-Noelle Bonnin-Verdal, Christine Ducos, Christian Barreau, Joel Roucolle, Pierre Sehabiague, Pierre Carolo, Florence Richard-Forget   +11 more
doaj   +1 more source

Mycotoxins: Risks, regulations and European co-operation [PDF]

Zbornik Matice Srpske za Prirodne Nauke, 2013
Mycotoxins and mycotoxicises have been problems of the past and the present, but scientific attention for mycotoxins did not start until the early 1960’s.
Van Egmond Hans P.
doaj   +1 more source

Preparative Separation and Purification of Trichothecene Mycotoxins from the Marine Fungus Fusarium sp. LS68 by High-Speed Countercurrent Chromatography in Stepwise Elution Mode

Marine Drugs, 2018
The contamination of foods and animal feeds with trichothecene mycotoxins is a growing concern for human and animal health. As such, large quantities of pure trichothecene mycotoxins are necessary for food safety monitoring and toxicological research.
Yong Liu, Xuezhen Zhou, C. Benjamin Naman, Yanbin Lu, Lijian Ding, Shan He   +5 more
doaj   +1 more source

Modification of Deoxynivalenol by a Fungal Laccase Paired with Redox Mediator TEMPO

Toxins, 2022
Mycotoxins such as deoxynivalenol introduce a health risk to the food supply and are costly to manage or avoid. Technologies for reducing or eliminating the toxicity of deoxynivalenol could be useful in a variety of processes, such as in preserving the ...
Hina Shanakhat, Susan P. McCormick, Mark Busman, Joseph O. Rich, Matthew G. Bakker   +4 more
doaj   +1 more source

Trichothecenes in Cereal Grains [PDF]

International Journal of Molecular Sciences, 2009
Trichothecenes are sesquiterpenoid mycotoxins associated with fusarium head blight (FHB) of cereals, with worldwide economic and health impacts. While various management strategies have been proposed to reduce the mycotoxin risk, breeding towards FHB-resistance appears to be the most effective means to manage the disease, and reduce trichothecene ...
Foroud, Nora A., Eudes, François
openaire   +2 more sources

A Novel Trichothecene Toxin Phenotype Associated with Horizontal Gene Transfer and a Change in Gene Function in Fusarium

Toxins, 2022
Fusarium trichothecenes are among the mycotoxins of most concern to food and feed safety. Production of these mycotoxins and presence of the trichothecene biosynthetic gene (TRI) cluster have been confirmed in only two multispecies lineages of Fusarium ...
Robert H. Proctor, Guixia Hao, Hye-Seon Kim, Briana K. Whitaker, Imane Laraba, Martha M. Vaughan, Susan P. McCormick   +6 more
doaj   +1 more source