Results 31 to 40 of about 18,425 (138)

Peripheral cytokine responses to Trichuris muris reflect those occurring locally at the site of infection [PDF]

, 2000
The study of human cellular immune responses to parasite infection under field conditions is very complex. Often, the only practical site from which to sample the cellular responses is the peripheral blood.
Betts, Catherine, Taylor, Matthew D, Taylor, Matthew D., Kathryn J. Else, Matthew D. Taylor, Betts, Catherine J., Else, Kathryn, Else, Kathryn J., Catherine J. Betts   +8 more
core   +1 more source

THE EFFECT OF Trichuris muris EGG ON THE GOBLET CELLS IN INTESTINE OF MICE (MUS MUCULUS)

Berkala Kedokteran, 2017
: Goblet cells are the immune response in the intestinal epithelium to produce mucus as a defense digestive tract mucosa caused by Trichuris muris infestation.
Lulu Hasna Ulfadila, Ahmad Husairi, Istiana Istiana   +2 more
doaj   +1 more source

Trichuris muris research revisited: a journey through time. [PDF]

Parasitology, 2013
The mouse whipworm Trichuris muris has long been used as a tractable model of human Trichuriasis. Here we look back at the history of T. muris research; from the definition of the species and determination of its life cycle, through to the complex immune
Hurst RJ, Else KJ.
europepmc   +2 more sources

No Structural Change in Mice Intestinal Gut-Associated Lymphoid Tissue After Trichuris muris Egg Infestation [PDF]

, 2022
Introduction: It has been known that  the infestation of Trichuris muris egg in the intestinal mice may induce a host immune ‎response to eliminate the worms.
Illiandri, Oski
core   +1 more source

A drug repurposing screen for whipworms informed by comparative genomics.

PLoS Neglected Tropical Diseases, 2023
Hundreds of millions of people worldwide are infected with the whipworm Trichuris trichiura. Novel treatments are urgently needed as current drugs, such as albendazole, have relatively low efficacy.
Avril Coghlan, Frederick A Partridge, María Adelaida Duque-Correa, Gabriel Rinaldi, Simon Clare, Lisa Seymour, Cordelia Brandt, Tapoka T Mkandawire, Catherine McCarthy, Nancy Holroyd, Marina Nick, Anwen E Brown, Sirapat Tonitiwong, David B Sattelle, Matthew Berriman   +14 more
doaj   +1 more source

Efficacy and safety of nitazoxanide, albendazole, and nitazoxanide-albendazole against Trichuris trichiura infection : a randomized controlled trial [PDF]

, 2012
BACKGROUND: The currently used anthelmintic drugs, in single oral application, have low efficacy against Trichuris trichiura infection, and hence novel anthelmintic drugs are needed.
Marco Albonico (159933), Jennifer Keiser, Alles Rainer, Benjamin Speich, Albonico Marco, Benjamin Speich (159922), Jan Hattendorf (113923), Shaali M. Ame (159925), Rainer Alles (159927), Marco Albonico, Utzinger Jürg, Hattendorf, J., Ame Shaali M., Jennifer Keiser (39606), Albonico, M., Jürg Utzinger, Hattendorf Jan, Ali, S. M., Shaali M Ame, Speich Benjamin, Rainer Alles, Speich, B., Keiser Jennifer, Utzinger, J., Keiser, J., Jürg Utzinger (39609), Ame, S. M., Ali Said M., Said M Ali, Alles, R., Said M. Ali (130132), Jan Hattendorf   +31 more
core   +2 more sources

Evaluation of an FDA approved library against laboratory models of human intestinal nematode infections [PDF]

, 2016
Treatment options for infections with soil-transmitted helminths (STH) - Ascaris lumbricoides, Trichuris trichiura and the two hookworm species, Ancylostoma duodenale and Necator americanus - are limited despite their considerable global health burden ...
Ivan Scandale (349072), Jennifer Keiser, Mireille Vargas (392661), Ivan Scandale, Noemi Cowan, Adelfio, Roberto, Panic, Gordana, Gordana Panic, Roberto Adelfio, Cowan, Noemi, Gordana Panic (507685), Roberto Adelfio (392660), Keiser, Jennifer, Scandale, Ivan, Jennifer Keiser (39606), Vargas, Mireille, Noemi Cowan (507684), Mireille Vargas   +17 more
core   +1 more source

Whipworms of south-east Asian rodents are distinct from Trichuris muris [PDF]

, 2020
The whipworm Trichuris muris is known to be associated with various rodent species in the northern hemisphere, but the species identity of whipworm infecting rodents in the Oriental region remains largely unknown.
Lakim, Maklarin, Konstans Wells, Ribas, Alexis, Morand, Serge, Chaisiri, Kittipong, Yuh Tuh, Fred, Agatsuma, Takeshi, Wells, Konstans, Saijuntha, Weerachai   +8 more
core   +1 more source

Mucosal immune responses following intestinal nematode infection. [PDF]

, 2014
In most natural environments, the large majority of mammals harbour parasitic helminths that often live as adults within the intestine for prolonged periods (1-2 years).
Harris, N. L., P. J. Cooper, Zaph, C, Cooper, P. J., C. Zaph, Cooper, PJ, Harris, NL, Zaph, C., Cooper, Philip, N. L. Harris   +9 more
core   +1 more source

Dihydrobenz[e][1,4]oxazepin-2(3H)-ones, a new anthelmintic chemotype immobilising whipworm and reducing infectivity in vivo.

PLoS Neglected Tropical Diseases, 2017
Trichuris trichiura is a human parasitic whipworm infecting around 500 million people globally, damaging the physical growth and educational performance of those infected.
Frederick A Partridge, Emma A Murphy, Nicky J Willis, Carole J R Bataille, Ruth Forman, Narinder Heyer-Chauhan, Bruno Marinič, Daniel J C Sowood, Graham M Wynne, Kathryn J Else, Angela J Russell, David B Sattelle   +11 more
doaj   +1 more source