Results 1 to 10 of about 52,474 (198)

Tricyclic antidepressants versus ‘active placebo’, placebo or no intervention for adults with major depressive disorder: a protocol for a systematic review with meta-analysis and Trial Sequential Analysis [PDF]

Systematic Reviews, 2021
Background Major depressive disorder is a common psychiatric disorder causing great burden on patients and societies. Tricyclic antidepressants are frequently used worldwide to treat patients with major depressive disorder.
Caroline Kamp Jørgensen, Sophie Juul, Faiza Siddiqui, Marija Barbateskovic, Klaus Munkholm, Michael Pascal Hengartner, Irving Kirsch, Christian Gluud, Janus Christian Jakobsen   +8 more
doaj   +2 more sources

Association of benzodiazepines, opioids and tricyclic antidepressants use and falls in trauma patients: Conditional effect of age. [PDF]

PLoS ONE, 2020
IntroductionThe relationship between benzodiazepines, opioids and tricyclic antidepressants and trauma is of great importance because of increased consumption and the growing evidence of a positive association among older adults.
Sergio Cordovilla-Guardia, Tania Bautista Molina, Cristina Franco-Antonio, Esperanza Santano-Mogena, Raquel Vilar-López   +4 more
doaj   +2 more sources

Beneficial and harmful effects of tricyclic antidepressants for adults with major depressive disorder: a systematic review with meta-analysis and trial sequential analysis [PDF]

BMJ Mental Health
Question Tricyclic antidepressants are used to treat depression worldwide, but the adverse effects have not been systematically assessed. Our objective was to assess the beneficial and harmful effects of all tricyclic antidepressants for adults with ...
Janus Christian Jakobsen, Christian Gluud, Marija Barbateskovic, Joanna Moncrieff, Irving Kirsch, Faiza Siddiqui, Michael Pascal Hengartner, Sophie Juul, Pascal Faltermeier, Johanne Juul Petersen, Caroline Barkholt Kamp, Andreas Torp Kristensen, Mark Abie Horowitz   +12 more
doaj   +2 more sources

Tricyclic antidepressants induce liver inflammation by targeting NLRP3 inflammasome activation [PDF]

Cell Communication and Signaling, 2023
Background Idiosyncratic drug-induced liver injury (IDILI) is common in hepatology practices and, in some cases, lethal. Increasing evidence show that tricyclic antidepressants (TCAs) can induce IDILI in clinical applications but the underlying ...
Wenqing Mu, Guang Xu, Zhilei Wang, Qiang Li, Siqiao Sun, Qin Qin, Zhiyong Li, Wei Shi, Wenzhang Dai, Xiaoyan Zhan, Jiabo Wang, Zhaofang Bai, Xiaohe Xiao   +12 more
doaj   +2 more sources

Claims Data Analysis on the Dispensing of Tricyclic Antidepressants Among Patients With Dementia in Germany [PDF]

Frontiers in Pharmacology, 2019
Objective: A restrictive use of tricyclic antidepressants (TCA) in patients with dementia (PwD) is recommended due to the hazard of anticholinergic side effects.
Philipp Hessmann, Philipp Hessmann, Jan Zeidler, Jona Stahmeyer, Sveja Eberhard, Jonathan Vogelgsang, Mona Abdel-Hamid, Claus Wolff-Menzler, Jens Wiltfang, Jens Wiltfang, Jens Wiltfang, Bernhard Kis   +11 more
doaj   +2 more sources

Impact of tricyclic antidepressants, selective serotonin reuptake inhibitors, and other antidepressants on overall survival of patients with advanced lung cancer from 2004 to 2014: University of Cincinnati experience [PDF]

Journal of International Medical Research, 2019
Objectives To evaluate and categorize the survival benefit of tricyclic antidepressants (TCAs) in lung cancer patients based on systematic computational drug repositioning data.
Nagla Fawzy Abdel Karim, Rammey Hassan, Nabeela Iffat Siddiqi, Ihab Eldessouki, Ola Gaber, Mohamed Rahouma, Mohamed Kamel, Mhender Yellu, Shuchi Gulati, Changchun Xie, Mohamed Magdy, Jane Pruemer   +11 more
doaj   +2 more sources

Rising Trend of Use of Antidepressants Induced Non-Puerperal Lactation: A Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2016
Non puerperal lactation or galactorrhea is a well known side effect of antipsychotic drugs but has been infrequently described with the use of antidepressants.
Prerna Kukreti, Wazid Ali, R.C. Jiloha
doaj   +1 more source

Antidepressants versus placebo for depression in primary care [PDF]

, 2009
Background Concern has been expressed about the relevance of secondary care studies to primary care patients specifically about the effectiveness of antidepressant medication.
Arroll, Bruce, Blashki, Grant, Elley, C. Raina, Fishman, Tana, Goodyear-Smith, Felicity A., Kenealy, Tim, Kerse, Ngaire, MacGillivray, Stephen   +7 more
core   +3 more sources

Effects of Imipramine and Lithium on the Suppression of Cell Proliferation in the Dentate Gyrus of the Hippocampus in Adrenocorticotropic Hormone-treated Rats [PDF]

, 2010
We examined the influence of chronic adrenocorticotropic hormone (ACTH) treatment on the number of Ki-67-positive cells in the dentate gyrus of the hippocampus in rats. ACTH treatment for 14 days decreased the number of such cells.
Asanuma, Masato, Doi, Maho, Gomita, Yutaka, Kawasaki, Hiromu, Kitamura, Yoshihisa, Matsunaga, Hisashi, Miyazaki, Ikuko, Nagamachi, Tomoko, Sendo, Toshiaki, Shinomiya, Kazuaki   +9 more
core   +1 more source

Painful Ejaculation with Cyclobenzaprine: A Case Report and Literature Review

Sexual Medicine, 2015
Introduction: Sexual dysfunction is a well‐known side effect of antidepressants. Painful ejaculation is a rare side effect that has been reported with the use of some psychiatric drugs such as triclyclic antidepressants.
Molly B. Kraus, MD, Christopher S. Wie, MD, Andrew W. Gorlin, MD, Eric S. Wisenbaugh, MD, David M. Rosenfeld, MD   +4 more
doaj   +1 more source