Results 91 to 100 of about 52,474 (198)

Acrocyanosis as a side effect of tricyclic antidepressants: a case report

open access: yesThe Turkish Journal of Pediatrics, 2003
Acrocyanosis is probably the most unusual side effect of tricyclic antidepressant drugs. In this paper, we report a 10-year-old boy with primary enuresis nocturna and attention deficit hyperactivity disorder who developed two episodes of ...
Işik Karakaya   +3 more
doaj  

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

REVERSİBLE MAO İNHİBİTORS İN THE TREATMENT OF PANİC DISORDERS

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Members of three classes of drugs have been shown to have efficacy-tricyclic antidepressants,monoamine oxidase inhibitors and benzodiazepins. Imipramine and clomipramine have been the tricyclic antidepressants most extensively studied.
Nesrin DİLBAZ   +3 more
doaj  

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

open access: yesBritish Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman   +3 more
wiley   +1 more source

Genitofemoral neuralgia : adding to the burden of chronic vulvar pain [PDF]

open access: yes, 2015
The vulva is a particularly common locus of chronic pain with neuropathic characteristics that occurs in women of any age, though most women with neuropathic type chronic vulvar pain will remain undiagnosed even following multiple physician visits. Here,
De Muynck, Martine   +2 more
core   +2 more sources

Cancer pain: current practice and emerging targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye   +5 more
wiley   +1 more source

Antidepressant Medications in Pregnancy [PDF]

open access: yes, 2004
Selective serotonin reuptake inhibitors (SSRIs) are considered first-line agents for the treatment of depression in pregnant women. SSRIs and tricyclic antidepressants (TCAs) are considered safe and effective in pregnant women, although some studies have
Huntington, Jane, Zantop, Veronika
core  

Efficacy and Safety of Pregabalin and Alpha‐Lipoic Acid Combination in Patients With Painful Diabetic Peripheral Neuropathy: A Randomized, Open‐Label, Non‐Inferiority, Phase IV Clinical Trial and Subgroup Analysis (OPTIMUM Study)

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To assess the efficacy and safety of alpha‐lipoic acid (ALA) and pregabalin, both as mono and combination therapy, for treating painful diabetic peripheral neuropathy (DPN) in patients with type 2 diabetes mellitus, with the hypothesis that pregabalin monotherapy is non‐inferior to combination therapy.
Tae Jung Oh   +14 more
wiley   +1 more source

Vortioxetine treatment for major depressive disorder with the co-morbidity of irritable bowel syndrome with diarrhoea: a case report

open access: yesPsychiatry and Clinical Psychopharmacology, 2018
Irritable bowel syndrome (IBS) is a complex condition that involves problems with bowel movements and belly pain, bloating, and gas. It is not life threatening, but can be a long-lasting problem that changes life quality.
Orkun Aydin, Pınar Ünal-Aydin
doaj   +1 more source

Antidepressants for treatment of depression in primary care:A systematic review and meta-analysis [PDF]

open access: yes, 2016
published_or_final_versio
Arroll, Bruce   +8 more
core   +2 more sources

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