Results 101 to 110 of about 34,503 (265)

Two-Dimensional Nuclear-Magnetic-Resonance Spectra of Selected Tricyclic Antidepressants [PDF]

, 1987
Two-dimensional nuclear magnetic resonance (2D NMR) spectroscopy has been used to assign C spectra of the tricyclic antidepressants imipramine and chlorimipramine. The 2D-INADEQUATE method was used to unambiguously assign the aromatic spectral region for
SHARON L. A. MUNRO, Hall, JG, JON G. HALL, Munro, Sla, DAVID J. CRAIK, Craik, DJ   +5 more
core   +1 more source

Management of Pain in the Intensive Care Unit: A Nordic Survey

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 8, September 2026.
ABSTRACT Background Pain is common in intensive care unit (ICU) patients with up to one‐third experiencing pain at rest and even more during mobilization and clinical procedures. This survey aimed to explore physicians' attitudes and preferences regarding pain management in adult ICU patients in the Nordic countries.
Benedikte Kollerup Madsen, Morten Hylander Møller, Stine Estrup, Lone Musaeus Poulsen, Bodil Steen Rasmussen, Kirstine Sylvester Conradsen, Thomas Lass Klitgaard, Asger Granfeldt, Theis Skovsgaard Itenov, Hans Christian Thorsen Meyer, Signe Tellerup Nielsen, Susanne Andi Iversen, Klaus Tjelle Kristiansen, Morten Heiberg Bestle, Kirsten Møller, Peter Hasse Møller Sørensen, Jeppe Veien Nygaard, Kristian Elgaard, Morten Rune Blichfeldt‐Eckhardt, Ann Christine Waarkjær Olsen, Mette Pedersen, Henrik Westy Hoffmeyer, Peter Martin Hansen, Helle Bundgaard, Marcus Ølgaard Møller, Jarl Sigaard, Kim Zillo Rokamp, Anne Craveiro Brøchner, Christoffer Sølling, Mika Valtonen, Anna‐Maria Kuivalainen, Annukka Vahtera, Stepani Bendel, Martin I. Sigurdsson, Per Martin Bådstøløkken, Fredrik Sjövall, Ole Mathiesen, Lars Peter Kloster Andersen   +37 more
wiley   +1 more source

Tricyclic antidepressants inhibit voltage-dependent calcium channels and Na⁺–Ca²⁺ exchange in rat brain cortex synaptosomes [PDF]

, 1990
We have used a resting (5 mM K+) or depolarizing (60 mM K+) choline-based medium, and a nondepolarizing sodium-based or choline-based medium, to characterize the inhibitory potential of tricyclic antidepressants against the voltage-dependent calcium ...
G. Beauchamp, R. Elie, P.-A. Lavoie
core   +1 more source

Deprescription of Psychotropics in Children and Adolescents: Systematic Review of Guidelines and Development of a Deprescribing Algorithm

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 3, September 2026.
ABSTRACT Background Psychotropics are increasingly prescribed in paediatrics despite limited evidence regarding their benefits and effectiveness. Although deprescribing approaches are established in adults, structured paediatric strategies remain poorly defined.
Paul‐Benoît Fargier, Mark Horowitz, Rodolphe Charles, Valérie Rousselon, Erik Fakra, Marie‐Noëlle Beyens, Marie‐Laure Laroche   +6 more
wiley   +1 more source

Efeito antidepressivo da agmatina em modelos animais de depressão [PDF]

, 2002
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Neurociências.A agmatina, amina formada pela descarboxilação enzimática da L-arginina, tem sido proposta como um novo ...
Zomkowski, Andréa Dias Elpo
core  

Selective serotonin reuptake inhibitors versus tricyclic and heterocyclic antidepressants: comparison of drug adherence. [PDF]

, 2000
BACKGROUND: Selective serotonin reuptake inhibitors are thought to have better discontinuation rates (i.e. less people dropping out) than tricyclic and heterocyclic antidepressant drugs.
Churchill, R, Hardy, R, C Barbui, Freemantle, N, Hardy, Rowan, R Churchill, N Freemantle, Lewis, G, Boynton, J, JR Geddes, Barbui, C, Mason, J M, Eccles, MP, G Lewis, Eccles, M P, JM Mason, Freemantle, Nick, Geddes, John, MP Eccles, Geddes, JR, J Boynton, Mason, JM, Hotopf, M, M Hotopf, Geddes, J R, R Hardy   +25 more
core   +1 more source

Psychotropic medication use among community dwellers with and without Parkinson's disease – A nationwide cohort study

British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2701-2710, August 2026.
Abstract Aims We studied the prevalence of psychotropic use and psychotropic polypharmacy in persons with Parkinson's disease (PD) during a 10‐year follow‐up, because longitudinal studies on this topic are scarce although non‐motor symptoms of PD are often treated with psychotropics.
Noora Nieminen, Anna‐Maija Tolppanen, Valtteri Kaasinen, Marjaana Koponen, Sirpa Hartikainen   +4 more
wiley   +1 more source

In perspective of meta-analyses: Are all of the antidepressants similar?

Psychiatry and Clinical Psychopharmacology, 2021
According to the World Health Organization (WHO) data and “the national disease burden and cost-effectiveness study” depression is the 4th cause of disease burden in Turkey.
Mesut Çetin, Cengizhan Açıkel
doaj  

Association Between a Body Shape Index and Epilepsy Among US Adults: Potential Indirect Pathway Through Depressive Symptoms

Brain and Behavior, Volume 16, Issue 8, August 2026.
ABSTRACT Background Epilepsy is a common and disabling brain disorder. Whether a body shape index (ABSI) is associated with epilepsy, and whether depressive symptoms may partly account for this association, remain unclear. Methods We analyzed 13,066 participants from the National Health and Nutrition Examination Survey 2013–2018.
Qiaoduan Feng, Xiujuan Mi, Hongbin Tang, Shaokun Yang, Can Wan, Jinsong You, Jun Tang   +6 more
wiley   +1 more source

A Systematic Review on Disease‐Modifying Therapies in Parkinsonian Disorders

Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 357-374, August 2026.
Parkinsonian disorders, including Parkinson's disease, Lewy body dementia, multiple system atrophy, and progressive supranuclear palsy, are progressive neurodegenerative conditions with no treatment options to slow disease progression. This systematic review provides an overview of evidence of disease‐modifying therapies that have been evaluated in ...
Pepijn P.N.M. Eijsvogel, Lars M.G. Smits, Philip H.C. Kremer, Geert Jan Groeneveld   +3 more
wiley   +1 more source