Results 111 to 120 of about 52,474 (198)

Narcolepsy and rapid eye movement sleep

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Since the first description of narcolepsy at the end of the 19th Century, great progress has been made. The disease is nowadays distinguished as narcolepsy type 1 and type 2. In the 1960s, the discovery of rapid eye movement sleep at sleep onset led to improved understanding of core sleep‐related disease symptoms of the disease (excessive ...
Francesco Biscarini, Lucie Barateau, Fabio Pizza, Giuseppe Plazzi, Yves Dauvilliers   +4 more
wiley   +1 more source

Antidepressants in the Treatment of Functional Dyspepsia: A Systematic Review and Meta-Analysis.

PLoS ONE, 2016
BackgroundAntidepressants have been empirically used in the treatment of functional dyspepsia (FD). However, results from recent clinical trials investigating their efficacy are conflicting.
Yaoyao Lu, Meng Chen, Zhiyin Huang, Chengwei Tang   +3 more
doaj   +1 more source

Migraine and Restless Legs Syndrome: A Meta‐Analysis

Journal of Sleep Research, EarlyView.
ABSTRACT Restless legs syndrome is a sensorimotor disorder of sleep/wake regulation that frequently coexists with migraine, affecting patients' quality of life. This study aimed to estimate the prevalence of restless legs syndrome in individuals with migraine and to explore the associated clinical, demographic and behavioural aspects.
Florindo d'Onofrio, Maria Cropano, Giada Panzino, Mariachiara Gaita, Giulio Cicarelli, Piero Barbanti, Gerardo Casucci, Simona Raimo, Antonio Costanzo   +8 more
wiley   +1 more source

Comparison of the efficacy of propranolol versus amitriptyline as monotherapy for prophylaxis of migraine

Journal of Family Medicine and Primary Care
Results: As a result, in Group A, the mean migraine attack severity in periods 1 and 2 was 5.88 2.69 and 5.41 2.48, respectively. In Group B, the mean was 5.15 2.75 in period 1 and 5.66 2.78 in period 2, respectively.
Krinaben M Patel, Kachhadia M Popatbhai, Roshni Xavier, Mohammed A S. Aramin, Khalid J F. Faris, Mohammed A Mateen, Priyadarshi Prajwal, Mohammed D M. Marsool, Hafsa Sheikh, Esra H. A G. Mohamed   +9 more
doaj   +1 more source

Functional and structural connectivity of thalamic subnuclei in major depressive disorder at 7 Tesla

Psychiatry and Clinical Neurosciences, EarlyView.
Aims Major depressive disorder (MDD) is widely considered to be a mood disorder characterized by altered connectivity. The thalamus plays an important role in MDD by connecting large areas of the brain. Here, we explored thalamic connectivity in MDD at the subnuclear level using ultra‐high‐field MRI.
Weijian Liu, Shu Liu, Jurjen Heij, Laurens A. van de Mortel, Luka Liebrand, Matthan Caan, Wietske van der Zwaag, Dick J. Veltman, Lin Lu, Moji Aghajani, Guido van Wingen   +10 more
wiley   +1 more source

The Role of Pharmacogenetic Biomarkers in Pain

Biomedicines
Background/Objectives: Pain—whether acute, chronic, or neuropathic—remains a leading cause of disability and reduced quality of life worldwide. Despite advances in pharmacologic options, interindividual variability in response and susceptibility to ...
Ivan Martin da Silva, Adrián Plaza-Díaz, Jesus Ruiz-Ramos, Ana Juanes-Borrego, Pau Riera   +4 more
doaj   +1 more source

Vulvodynia; an under-recognized disease [PDF]

, 2016
Vulvodynia is a chronic condition which affects an increasing number of women; it presents currently an incidence that is higher than had previously been estimated.
Georgescu, Simona Roxana, Mitran, Cristina I., Mitran, Mădălina I., Sârbu, Maria I., Tampa, Mircea   +4 more
core   +2 more sources

Acute prefrontal hemodynamic responses to intermittent theta burst stimulation correlate with current depression and episode recurrence: A cross‐sectional study

Psychiatry and Clinical Neurosciences, EarlyView.
Background Mounting evidence has indicated that multiple major depressive disorder (MDD) episodes are correlated with brain morphometric changes that confer an increased recurrence risk. Functional abnormalities underlying this recurrent vulnerability remain underexplored.
Minxia Jin, Adam W.L. Xia, Wanda M.W. Chau, Nancy M.X.Y. Shi, Penny P. Qin, Bella B.B. Zhang, Rebecca L.D. Kan, Alvin H.P. Tang, Tim T.Z. Lin, Sharie X. Wang, Dicky W.S. Chung, Frank Padberg, Georg S. Kranz   +12 more
wiley   +1 more source

Development of Visible Spectrophotometric Methods for the Determination of Tricyclic Antidepressants Based on Formation of Molecular Complexes with p-Benzoquinones. [PDF]

Int J Mol Sci, 2023
Ciuca MD, Racovita RC.
europepmc   +1 more source

Possible involvement of keratinocyte‐derived microvesicle particles in human photosensitivity disorders

Photochemistry and Photobiology, EarlyView.
In this model, ROS generated by UVB result in PAFR agonists acting upon the PAFR resulting in MVP generation release via the enzyme aSMase. In photosensitivity, there are increased ROS, resulting in augmented PAF agonists and increased MVP release. This process can be blocked by aSMase inhibitors.
Risha Annamraju, Madison S. Owens, Anita Thyagarajan, Danielle A. Corbin, Catherine M. T. Sherwin, Jade Bryant, Garrett W. Fisher, Winston R. Owens, Alycia Ketter, Aadil Umerani, Craig A. Rohan, Michael G. Kemp, Robyn K. Crow, Jeffrey B. Travers   +13 more
wiley   +1 more source