Results 51 to 60 of about 123,610 (151)

Trigeminal neuralgia and its variants. Management and diagnosis [PDF]

, 2020
Trigeminal neuralgia (TN) and trigeminal autonomic cephalalgias (TACs) can cause severe facial pain. The differential diagnosis can be very challenging as both present with a sudden, usually unilateral, severe, recurrent pain in the distribution of one ...
Besi, E, Zakrzewska, JM
core   +1 more source

High‐altitude headache: Insights into pathophysiology and potential treatment implications

The Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude headache occurs during prolonged exposure to low oxygen, such as during ascent to high altitude. Several risk factors increase its likelihood, with the degree of hypoxia, often driven by rapid ascent to greater altitudes, being the most prominent factor.
Marika Falla, Florian Frank, Giacomo Strapazzon, Justin Lawley   +3 more
wiley   +1 more source

Cracked tooth syndrome mimicking trigeminal autonomic cephalalgia: A report of four cases

, 2017
Background: This report describes four cases of cracked tooth syndrome secondary to traumatic occlusion that mimicked trigeminal autonomic cephalalgias. All patients were referred by general practitioners to the Orofacial Pain Clinic at Nihon University ...
Young, Andrew L., Imamura, Yoshiki, Khan, Junad, Noma, Noboru, Watanabe, Kosuke, Shimizu, Kohei   +5 more
core   +1 more source

Assessment of Cerebral Perfusion Asymmetry in Chronic Migraine Patients Using Intravoxel Incoherent Motion (IVIM)–Derived Pseudodiffusion Coefficient and Perfusion Fraction

NMR in Biomedicine, Volume 39, Issue 11, November 2026.
ROI‐based quantitative IVIM‐DWI analysis demonstrated significantly greater interhemispheric asymmetry of the composite perfusion parameter fD* in the posterior thalamus in chronic migraine during the interictal phase compared with control subjects. In contrast, pain‐implicated cortical loci showed no significant interhemispheric perfusion asymmetry ...
Yunus Emre Senturk, Ahmet Peker, Sabahattin Yuzkan, Huseyin Ekin Ergin, Eser Bulus, Mohammed Salman Shazeeb   +5 more
wiley   +1 more source

A translational in vivo model of trigeminal autonomic cephalalgias:therapeutic characterization

, 2012
Trigeminal autonomic cephalalgias are highly disabling primary headache disorders, characterized by severe unilateral head pain and associated ipsilateral cranial autonomic features.
Lasalandra, Michele P, Goadsby, Peter J; id_orcid, Holland, Philip R; id_orcid, Akerman, Simon, Summ, Oliver   +4 more
core   +1 more source

Sleep disturbances in trigeminal autonomic cephalalgias: clinical implications and pathophysiological insights — a systematic review

Headache Medicine
Introduction Trigeminal autonomic cephalalgias (TACs), particularly cluster headache, are characterized by severe attacks with marked circadian patterns, frequently arising during sleep.
Giulia Miranda Reale Lemos, Camila Lopes Lima, Carolina Veruska Rodrigues de Deus Garrido Sales   +2 more
doaj   +2 more sources

Human brain matters: Navigating the neuropathology of COVID‐19

Brain Pathology, Volume 36, Issue 6, November 2026.
Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland, Angelica Scaramuzza, Marianna Bugiani, Wilma D. J. van de Berg, Jinte Middeldorp   +4 more
wiley   +1 more source

Comparative Study of Clinical Characteristics According to Pain Distribution in Lingual Burning Mouth Syndrome

Journal of Oral Rehabilitation, Volume 53, Issue 11, Page 2150-2157, November 2026.
Tongue pain mapping in 256 patients with lingual burning mouth syndrome identified distinct clinical phenotypes according to pain distribution. Wider pain areas were associated with higher pain intensity and poorer oral health‐related quality of life, supporting individualised assessment and targeted management.
Yoohyun Sim, Na‐Yeon Ha, Seok‐Jae Ko, Jae‐Woo Park, Jinsung Kim   +4 more
wiley   +1 more source

Neuromodulatory and interventional therapies in trigeminal autonomic cephalalgias: a systematic review

Headache Medicine
Introduction Trigeminal autonomic cephalalgias (TACs) are rare primary headache disorders characterized by severe unilateral pain and ipsilateral cranial autonomic symptoms, encompassing cluster headache, paroxysmal hemicrania, hemicrania continua, and ...
Beatriz Mascarenhas Nunes, Ellen Fernanda Lima de Souza, Ádila Fernanda Pereira Martins, alley Ferraro Oliveira   +3 more
doaj   +2 more sources

Distribution of Big Tau Isoforms in the Human Central and Peripheral Nervous System

Annals of Neurology, Volume 100, Issue 4, Page 709-736, October 2026.
Objective Tau is widely studied in neurodegeneration, yet most work has focused on canonical brain tau isoforms. A longer isoform, “big tau,” produced by inclusion of exon 4a, is expressed in the peripheral nervous system (PNS) and central nervous system (CNS) regions.
Rama Krishna Koppisetti, Nicolas R. Barthélemy, Kanta Horie, Cindy V. Ly, Kaleigh F. Roberts, Srinivas Koutarapu, Richard J. Perrin, Erin E. Franklin, Chiara Pedicone, Joshua Orrick, Justin Melendez, Timothy M. Miller, Chihiro Sato, Nupur Ghoshal, Alison M. Goate, Celeste M. Karch, Randall J. Bateman, Soumya Mukherjee   +17 more
wiley   +1 more source