Results 61 to 70 of about 123,610 (151)

Trigeminal Nerve Stimulation for Disorders of Consciousness: A Narrative Review of Potential Mechanisms, Clinical Evidence, and Future Perspectives

CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
Preclinical studies indicate that Trigeminal Nerve Stimulation (TNS) treats Disorders of Consciousness (DoC) by activating neural pathways that promote the release of orexin, dopamine, and norepinephrine. Additionally, TNS modulates cerebral hemodynamics and immunoregulation to enhance consciousness in experimental animals.
Haodong Niu, Yilin Zhang, Nan Wang, Xiaoke Chai, Yiyi Zhai, Zhiyao Zheng, Yangxi Xu, Yitong Jia, Kefei Wan, Sipeng Zhu, Tianqing Cao, Qiheng He, Minghao Liu, Zhuoyang Li, Yichen Wang, Haitao Huang, Juanning Si, Yi Yang, Jizong Zhao   +18 more
wiley   +1 more source

Hemicrania Continua Associated with Classic Scintillating Scotoma

Case Reports in Neurology, 2018
Hemicrania continua (HC) is a rare primary headache disorder, characterized by persistent unilateral pain associated with cranial autonomic symptoms and prompt response to indomethacin.
Eva Auffenberg, Friedemann Bender, Tobias Freilinger   +2 more
doaj   +1 more source

Migraine in Older Adults: Age‐Related Clinical Features From the Italian RICe Registry

European Journal of Neurology, Volume 33, Issue 10, October 2026.
This multicentre study of 3477 patients from 30 Italian headache centres identified distinct age‐related patterns in migraine. Older adults more frequently presented with chronic migraine, higher monthly migraine frequency, lower pain intensity, and medication‐overuse headache, as well as distinct trigger and preventive treatment patterns.
Giulia Paparella, Luigi Francesco Iannone, Giulia Paparella, Grazia Sances, Roberto De Icco, Gloria Vaghi, Cristina Tassorelli, Andrea Burgalassi, Francesco De Cesaris, Alberto Chiarugi, Francesca Gabriele, Raffaele Ornello, Simona Sacco, Maria Pia Prudenzano, Martino Gentile, Damiano Paolicelli, Giorgia Dalla Volta, Marco Bolchini, Innocenzo Rainero, Elisa Rubino, Maria Albanese, Fabrizio Vernieri, Gianluca Coppola, Gianluca Avino, Edoardo Mampreso, Delfina Ferrandi, Marta Altieri, Stefania Battistini, Antonio Granato, Simona Guerzoni, Antonio Russo, Marina de Tommaso, the RICe Study Group, Paola Merlo, Alessandro Viganò, Massimo Alessandri, Lucia Princiotta Cariddi, Milena Taglioli, Mariarosaria Valente, Rosaria Rapisarda, Alessandro Tiezzi, Giovanna Ballerini, Giovanna Viticchi, Catello Vollono, Luisa Fofi, Antonio Montisano, Licia Grazzi, Eugenia Rota   +47 more
wiley   +1 more source

Trait- and Frequency-Dependent Dysfunctional Habituation to Trigeminal Nociceptive Stimulation in Trigeminal Autonomic Cephalalgias

, 2018
We investigated whether the stimulation frequency, the pain phases and different diagnoses of trigeminal autonomic cephalalgias (TACs) may influence the habituation to pain. We studied the habituation of the nociceptive blink reflex (nBR) R2 responses at
Anna Ambrosini, Giorgio Sandrini, Sandrini, Giorgio, Pierelli, Francesco, Evangelista, Maurizio, Armando Perrotta, Francesco Pierelli, Perrotta, Armando, Gianluca Coppola, Anastasio, Maria Grazia, Ambrosini, Anna, Maurizio Evangelista, Parisi, Vincenzo, Maria Grazia Anastasio, Vincenzo Parisi, Coppola, Gianluca, Mariano Serrao, Roberto De Icco, De Icco, Roberto, Serrao, Mariano, Pierelli F., Ambrosini A., Anastasio M. G., Sandrini G., Evangelista M., Serrao M., Perrotta A., Coppola G., De Icco R., Parisi V.   +29 more
core   +1 more source

Cancer‐related pain: A bidirectional modulator of cancer progression

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
CRP and tumour progression engage in a dynamic, bidirectional circuit mediated by multiple mechanisms involving neuroimmunology and cancer ‐neuroscience. Analgesic interventions may affect tumour progression, while anticancer therapies can influence pain. Targeting pain in cancer may have promising therapeutic value in cancer progression.
Junzhe He, Yu Zhang, Qian Liu, Biao Yan, Peiwei Chai, Renbing Jia   +5 more
wiley   +1 more source

The Prevalence of Neuropathic Pain in Multiple Sclerosis—A Systematic Review and Meta‐Analysis Using the NeuPSIG Algorithm

European Journal of Pain, Volume 30, Issue 8, September 2026.
ABSTRACT Background and Objectives Multiple sclerosis (MS) is a neurodegenerative disorder frequently leading to neuropathic pain. Due to the neurodegenerative nature, the diagnosis of neuropathic pain remains challenging. A grading system has been developed providing an overview of diagnostic certainty (i.e., possible, probable and definite). Since no
Rasmus C. Jungersen, Victor K. Baccaro, Lars G. Hvid, Ulrik Dalgas, Morten Hoegh   +4 more
wiley   +1 more source

The Treatment of Trigeminal Autonomic Cephalalgias: An Overview

, 2019
Trigeminal autonomic cephalalgias (TACs) are primary headaches that include cluster headache (CH), paroxysmal hemicrania (PH), and short-lasting unilateral neuralgiform headache attacks (SUNHAs) with conjunctival injection and tearing (SUNCT) or cranial
Antonaci, Fabio, Ramusino, Matteo Cotta, Perini, Giulia, Costa, Alfredo   +3 more
core   +1 more source

Primary headache disorders and neuro-ophthalmologic manifestations

Eye and Brain, 2012
Daniel P Schwartz, Matthew S RobbinsDepartment of Neurology, Montefiore Headache Center, Albert Einstein College of Medicine, Bronx, NY, USAAbstract: Headache is an extraordinarily common complaint presenting to medical practitioners in all arenas and ...
Schwartz DP, Robbins MS
doaj  

Migraine: Epidemiology, Risk Factors, Pathophysiology, and Treatment

MedComm, Volume 7, Issue 9, September 2026.
Migraine is a highly prevalent, female‐predominant, and disabling brain disorder shaped by genetic susceptibility, hormonal influences, modifiable attack factors, and comorbidity‐related progression. This review integrates current evidence on migraine epidemiology, phase‐specific neurovascular and neuroglial mechanisms, including CGRP signaling and ...
Weiwei Lu, Yuan Zhang, Chen Shi, Yu Tao, Shaoxin Li, Yufang Sun, Fuhai Ji, Dongsheng Jiang, Terrance P. Snutch, Jin Tao   +9 more
wiley   +1 more source

MR Tractography in Short Lasting Unilateral Neuralgiform Headache Attacks with Conjunctival Injection and Tearing (SUNCT) Patients: Case Reports

, 2017
Background. Short-lasting unilateral neuralgiform headache attack with conjunctival injection and tearing (SUNCT) is one of the trigeminal autonomic cephalalgias where neurovascular compression was detected in neuroimaging in recent ...
Coşkun, Özlem, Yildirim, Funuzar, Cetinkaya, Rumeysa, Vurallı, Doğa, Ucler, Serap, Takmaz, Suna Akin, Uçar, Murat   +6 more
core   +1 more source