Results 81 to 90 of about 5,010,147 (298)

Triglyceride-Glucose Index Levels Positively Associated with Higher Risk of Low Muscle Mass in Patients with Type 2 Diabetes [PDF]

Qinying Zhao,* Ziyue Zhang,* Shuo Li, Ming Liu Department of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ming Liu,
Li S, Zhang Z, Liu M, Zhao Q
core  

Estimation of HOMA-IR and Triglyceride-Glucose Index in Single Females with PCOS

This study aims to estimate insulin resistance (IR) in single females with polycystic ovarian syndrome. A cross-sectional study was designed to assess the insulin hormone, blood glucose level, IR biomarker, triglyceride-glucose index, serum high-density ...
Omer , Bakhtawar Z., Younis, Zheyan T., Taher , Zahraakhan M., Asaad, Dunya A.   +3 more
core   +1 more source

The Triglyceride-Glucose Index Predicts Peripheral Artery Disease Complexity

, 2020
AYHAN, Hüseyin/0000-0002-9991-7307Background/aim: High levels of triglyceride (TG) and fasting blood glucose (FBG) values increase atherosclerosis risk.
Karaduman, Bilge Duran, Ayhan, Hüseyin, Bozkurt, Engin, Keles, Telat, Duran Karaduman, Bilge   +4 more
core   +1 more source

Low‐Density Lipoprotein Receptor‐Targeted Biomimetic Nanoplatform Suppresses Glioblastoma Stemness and Remodels Antitumor Immunity via Dual Metabolic Disruption

Advanced Science, EarlyView.
A low‐density lipoprotein receptor‐oriented biomimetic nanoplatform couples brain‐tumor delivery with a mechanistically matched regorafenib‐erythrodiol combination. Concurrent disruption of autophagic nutrient salvage and cholesterol homeostasis collapses bioenergetic and signaling support, suppresses glioblastoma stemness, and promotes immunogenic ...
Yining Jiang, Wenzhuo Yang, Wenting Cheng, Jing Zuo, Lin Pan, Sheng Zhong, Ren Geng, Yao Zhao, Zijian Chen, Canhua Huang, Yang Bai, Liyan Zhao, Yunqian Li   +12 more
wiley   +1 more source

Triglyceride-glucose index: a surrogate marker of homeostasis model assessment of insulin resistance to predict diabetic nephropathy

Journal of the Pakistan Medical Association
Objectives: To determine the association of triglyceride-glucose index with homeostasis model assessment of insulin resistance in type 2 diabetes mellitus patients, and to determine the association of triglyceride-glucose index with urinary albumin-to ...
Sania Khan, Shazia Qayyum, Muhammad Nadim Akbar Khan   +2 more
doaj   +1 more source

The Role of Triglyceride-Glucose Index in Central Retinal Artery Occlusion

International Ophthalmology
Abstract Purpose:To evaluate the correlation between the Triglyceride-Glucose (TyG) index and newly diagnosed cases of central retinal artery occlusion (CRAO) in patients. Methods: The research involved 51 patients diagnosed with central retinal artery occlusion (CRAO) and a control group consisting of 50 healthy volunteers matched for age and ...
Hatice Aslan Sirakaya, Bekir Ayyildiz, Ibrahim Ismet Sert, Bekir Kucuk, Semra Koca, Ender Sirakaya   +5 more
openaire   +2 more sources

The Triglyceride-Glucose Index: A Potential Simple Screening Tool for Insulin Resistance in Young Adults [PDF]

Background: Insulin resistance is a key factor in the development of metabolic diseases, which are increasingly prevalent in young adults. Early detection is crucial for timely intervention.
Rismawati Yaswir, Efrida, Syofiati, Elfira Yusri, Husni, Kenny   +5 more
core   +1 more source

Hepatic Lipid Stress Drives Metabolic Dysfunction‐Associated Steatohepatitis Progression through FTO O‐GlcNAcylation‐Induced m6A Demethylation of HRAS

Advanced Science, EarlyView.
Lipid stress drives O‐GlcNAcylation of the m6A demethylase FTO at Ser195, enhancing its stability and demethylase activity. This modification removes m6A from HRAS mRNA, preventing its degradation and activating PI3K/AKT signaling to promote hepatic steatosis and inflammation.
Jia‐Xin Yin, Yan‐Lai Zhang, Qun Liu, Rui Liu, Hai‐Yang Yuan, Sui‐Dan Chen, Ming‐Hua Zheng, Kai Wang, Ni Tang, Ai‐Long Huang   +9 more
wiley   +1 more source

Additional file 1 of Association between the triglyceride-glucose index and the presence and prognosis of coronary microvascular dysfunction in patients with chronic coronary syndrome

, 2023
Additional file1: Figure S1. Correlation between TyG index and caIMR in various subgroups. TyG index triglyceride-glucose index, caIMR coronary angiography-derived index of microcirculatory resistance, DM diabetes mellitus, CAD coronary artery ...
Siqi Li (2283472), Fuad A. Abdu (10899336), Abdul-Quddus Mohammed (10899339), Guoqing Yin (8065811), Ayman A. Mohammed (14030018), Xian Lv (11135643), Tingting Shi (1725919), Bin Xu (10691), Wenliang Che (4556971), Jassur Galip (15243598), Lu Liu (171341), Huiying Chen (721096), Minying Wan (15465136), Wen Zhang (7555), Redhwan M. Mareai (14030021), Yawei Xu (126970)   +15 more
core   +1 more source

Hepatocyte CBX2 Safeguards Hepatic Lipid Homeostasis by Elevating Ca2+‐CaMKK2‐AMPK Signaling to Counter MASLD

Advanced Science, EarlyView.
In hepatocytes, CBX2 promotes H3K4me3 enrichment at the Orai1 promoter to enhance Orai1 transcriptional activation, thereby increasing intracellular Ca2+ levels. The elevated Ca2+ activates the CaMKK2‐AMPK signaling cascade, resulting in ACC phosphorylation and downstream metabolic regulation. This cascade suppresses de novo lipogenesis (Fasn, Acc, Scd‐
Xiang Wei, Li Lin, Xiuyun Wang, Hui Du, Menglong Zhang, Kechao Tang, Han Gao, Xinrui Xie, Jingya Gao, Xu Wang, Zhenglin Wang, Siwei Huang, Lei Zhang, Fang Gu, Gong‐Hong Wei, Yinliang Qi, Wei Chen, Yongsheng Chang, Huabing Zhang   +18 more
wiley   +1 more source